Search Results - "MAIRBÄURL, Heimo"

Squeezing viscous blood through narrow pipes, and other problems of high‐altitude polycythaemia by Mairbäurl, Heimo

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Red blood cells in sports: effects of exercise and training on oxygen supply by red blood cells by Mairbäurl, Heimo

“…During exercise the cardiovascular system has to warrant substrate supply to working muscle. The main function of red blood cells in exercise is the transport…”
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Exposure to 16 h of normobaric hypoxia induces ionic edema in the healthy brain by Biller, Armin, Badde, Stephanie, Heckel, Andreas, Guericke, Philipp, Bendszus, Martin, Nagel, Armin M., Heiland, Sabine, Mairbäurl, Heimo, Bärtsch, Peter, Schommer, Kai

“…Following prolonged exposure to hypoxic conditions, for example, due to ascent to high altitude, stroke, or traumatic brain injury, cerebral edema can develop…”
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Neocytolysis: How to Get Rid of the Extra Erythrocytes Formed by Stress Erythropoiesis Upon Descent From High Altitude by Mairbäurl, Heimo

“…Neocytolysis is the selective destruction of those erythrocytes that had been formed during stress-erythropoiesis in hypoxia in order to increase the oxygen…”
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High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart by ANDRASSY, Martin, VOLZ, Hans C, BEA, Florian, HARDT, Stefan E, HUMPERT, Per M, BIANCHI, Marco E, MAIRBÄURL, Heimo, NAWROTH, Peter P, REMPPIS, Andrew, KATUS, Hugo A, BIERHAUS, Angelika, IGWE, John C, FUNKE, Benjamin, EICHBERGER, Sebastian N, KAYA, Ziya, BUSS, Sebastian, AUTSCHBACH, Frank, PLEGER, Sven T, LUKIC, Ivan K

“…High-mobility group box-1 (HMGB1) is a nuclear factor released by necrotic cells and by activated immune cells. HMGB1 signals via members of the toll-like…”
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Geographical ancestry affects normal hemoglobin values in high-altitude residents by Mairbäurl, Heimo, Gassmann, Max, Muckenthaler, Martina U

“…Increasing the hemoglobin (Hb) concentration is a major mechanism adjusting arterial oxygen content to decreased oxygen partial pressure of inspired air at…”
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Extreme Terrestrial Environments: Life in Thermal Stress and Hypoxia. A Narrative Review by Burtscher, Martin, Gatterer, Hannes, Burtscher, Johannes, Mairbäurl, Heimo

“…Living, working and exercising in extreme terrestrial environments are challenging tasks even for healthy humans of the modern new age. The issue is not just…”
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In Search of a Sensor: How Does CO2 Regulate Alveolar Ion Transport? by Baloğlu, Emel, Mairbäurl, Heimo

“…Balogu and Mairbaurl asserts that levels of carbon dioxide (CO2), which is an end product of cellular energy metabolism, are well controlled by respiration…”
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Hypoxia Aggravates Inhibition of Alveolar Epithelial Na-Transport by Lipopolysaccharide-Stimulation of Alveolar Macrophages by Baloglu, Emel, Velineni, Kalpana, Ermis-Kaya, Ezgi, Mairbäurl, Heimo

“…Inflammation and hypoxia impair alveolar barrier tightness, inhibit Na- and fluid reabsorption, and cause edema. We tested whether stimulated alveolar…”
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Physiological aspects of high-altitude pulmonary edema by Bartsch, Peter, Mairbaurl, Heimo, Maggiorini, Marco, Swenson, Erik R

“…1 Division of Sports Medicine, Department of Internal Medicine, Medical University Hospital, Heidelberg, Germany; and 2 Department of Cardiology, Medical…”
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Inhaled budesonide does not prevent acute mountain sickness after rapid ascent to 4559 m by Berger, Marc Moritz, Macholz, Franziska, Sareban, Mahdi, Schmidt, Peter, Fried, Sebastian, Dankl, Daniel, Niebauer, Josef, Bärtsch, Peter, Mairbäurl, Heimo

“…Recent studies showed that inhaled budesonide (200 µg twice per day) reduced the incidence of acute mountain sickness (AMS) after passive ascent to 3700 and…”
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S287: HEMOGLOBIN AND FERRITIN LEVELS ADJUST DIFFERENTLY TO MODERATE AND HIGH ALTITUDE IN DIFFERENT WORLD REGIONS: EVIDENCE FOR A VERY PRECISE OXYGEN SENSING SYSTEM by Gassmann, Max, Muckenthaler, Martina, Mairbäurl, Heimo

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Identification of a Prognostic Hypoxia-Associated Gene Set in IDH-Mutant Glioma by Dao Trong, Philip, Rösch, Saskia, Mairbäurl, Heimo, Pusch, Stefan, Unterberg, Andreas, Herold-Mende, Christel, Warta, Rolf

“…Glioma growth is often accompanied by a hypoxic microenvironment favorable for the induction and maintenance of the glioma stem cell (GSC) phenotype. Due to…”
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The Increase in Hemoglobin Concentration With Altitude Differs Between World Regions and Is Less in Children Than in Adults by Mairbäurl, Heimo, Kilian, Samuel, Seide, Svenja, Muckenthaler, Martina U., Gassmann, Max, Benedict, Rukundo K.

“…To compensate for decreased oxygen partial pressure, high‐altitude residents increase hemoglobin concentrations [Hb]. The elevation varies between world…”
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The Hen or the Egg: Impaired Alveolar Oxygen Diffusion and Acute High-altitude Illness? by Mairbäurl, Heimo, Dehnert, Christoph, Macholz, Franziska, Dankl, Daniel, Sareban, Mahdi, Berger, Marc M

“…Individuals ascending rapidly to altitudes >2500 m may develop symptoms of acute mountain sickness (AMS) within a few hours of arrival and/or high-altitude…”
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Preserved right ventricular function but increased right atrial contractile demand in altitude-induced pulmonary hypertension by Sareban, Mahdi, Perz, Tabea, Macholz, Franziska, Reich, Bernhard, Schmidt, Peter, Fried, Sebastian, Mairbäurl, Heimo, Berger, Marc M., Niebauer, Josef

“…Purpose Ascent to high altitude increases right ventricular (RV) afterload and decreases myocardial energy supply. This study evaluates physiologic variables…”
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Hemoglobin is an oxygen-dependent glutathione buffer adapting the intracellular reduced glutathione levels to oxygen availability by Fenk, Simone, Melnikova, Elizaveta V., Anashkina, Anastasia A., Poluektov, Yuri M., Zaripov, Pavel I., Mitkevich, Vladimir A., Tkachev, Yaroslav V., Kaestner, Lars, Minetti, Giampaolo, Mairbäurl, Heimo, Goede, Jeroen S., Makarov, Alexander A., Petrushanko, Irina Yu, Bogdanova, Anna

“…Fast changes in environmental oxygen availability translate into shifts in mitochondrial free radical production. An increase in intraerythrocytic reduced…”
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The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration by Gdynia, Georg, Sauer, Sven W., Kopitz, Jürgen, Fuchs, Dominik, Duglova, Katarina, Ruppert, Thorsten, Miller, Matthias, Pahl, Jens, Cerwenka, Adelheid, Enders, Markus, Mairbäurl, Heimo, Kamiński, Marcin M., Penzel, Roland, Zhang, Christine, Fuller, Jonathan C., Wade, Rebecca C., Benner, Axel, Chang-Claude, Jenny, Brenner, Hermann, Hoffmeister, Michael, Zentgraf, Hanswalter, Schirmacher, Peter, Roth, Wilfried

“…The high-mobility group box 1 (HMGB1) protein has a central role in immunological antitumour defense. Here we show that natural killer cell-derived HMGB1…”
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The role of hypoxia-induced modulation of alveolar epithelial Na+- transport in hypoxemia at high altitude by Baloglu, Emel, Nonnenmacher, Gabriel, Seleninova, Anna, Berg, Lena, Velineni, Kalpana, Ermis-Kaya, Ezgi, Mairbäurl, Heimo

“…Reabsorption of excess alveolar fluid is driven by vectorial Na+-transport across alveolar epithelium, which protects from alveolar flooding and facilitates…”
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High‐altitude pulmonary hypertension is associated with a free radical‐mediated reduction in pulmonary nitric oxide bioavailability by Bailey, Damian M., Dehnert, Christoph, Luks, Andrew M., Menold, Elmar, Castell, Christian, Schendler, Guido, Faoro, Vitalie, Gutowski, Mariusz, Evans, Kevin A., Taudorf, Sarah, James, Philip E., McEneny, J., Young, Ian S., Swenson, Erik R., Mairbäurl, Heimo, Bärtsch, Peter, Berger, Marc M.

“…High altitude (HA)‐induced pulmonary hypertension may be due to a free radical‐mediated reduction in pulmonary nitric oxide (NO) bioavailability. We…”
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