Search Results - "MAHONEY, M"
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Combination cancer immunotherapy and new immunomodulatory targets
Published in Nature reviews. Drug discovery (01-08-2015)“…Key Points Tumours actively inhibit the antitumour immune response. The programmed cell death protein 1–programmed cell death 1 ligand 1 (PD1–PDL1) pathway has…”
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Cluster secondary ion mass spectrometry of polymers and related materials
Published in Mass spectrometry reviews (01-03-2010)“…Cluster secondary ion mass spectrometry (cluster SIMS) has played a critical role in the characterization of polymeric materials over the last decade, allowing…”
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The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma
Published in Clinical therapeutics (01-04-2015)“…Abstract Purpose Blocking the interaction between the programmed cell death (PD)-1 protein and one of its ligands, PD-L1, has been reported to have impressive…”
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Overhang of the Femoral Component in Total Knee Arthroplasty: Risk Factors and Clinical Consequences
Published in Journal of bone and joint surgery. American volume (01-05-2010)“…Recently, much attention has been directed to femoral component overhang in total knee arthroplasty. The purposes of this study were to describe the prevalence…”
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Family of BODIPY Photocages Cleaved by Single Photons of Visible/Near-Infrared Light
Published in Journal of the American Chemical Society (13-06-2018)“…Photocages are light-sensitive chemical protecting groups that provide external control over when, where, and how much of a biological substrate is activated…”
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Learning from PD-1 Resistance: New Combination Strategies
Published in Trends in molecular medicine (01-06-2016)“…Only a minority of cancer patients respond to anti PD-1 immunotherapy. A recent study demonstrates that PD-1 therapy-resistant melanoma patients present…”
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Shift Work, Jet Lag, and Female Reproduction
Published in International journal of endocrinology (01-01-2010)“…Circadian rhythms and “clock gene” expression are involved in successful reproductive cycles, mating, and pregnancy. Alterations or disruptions of biological…”
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Inducing Molecular Aggregation of Polymer Semiconductors in a Secondary Insulating Polymer Matrix to Enhance Charge Transport
Published in Chemistry of materials (28-01-2020)“…Polymer semiconductors (PSCs) are a desirable class of materials for next-generation electronics. However, the conformational complexity associated with…”
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Sleep, rhythms, and the endocrine brain: influence of sex and gonadal hormones
Published in The Journal of neuroscience (09-11-2011)“…While much is known about the mechanisms that underlie sleep and circadian rhythms, the investigation into sex differences and gonadal steroid modulation of…”
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irRECIST for the Evaluation of Candidate Biomarkers of Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma: Analysis of a Phase II Prospective Clinical Trial
Published in Clinical cancer research (01-04-2019)“…Immune-related RECIST (irRECIST) were designed to capture atypical responses seen with immunotherapy. We hypothesized that, in patients with metastatic clear…”
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Multimodality imaging review of breast vascular lesions
Published in Clinical radiology (01-04-2022)“…Breast vasculature is visualised on all screening and diagnostic imaging of the breast. Various vascular breast lesions exist, spanning from chronic systemic…”
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Epileptogenesis in organotypic hippocampal cultures has limited dependence on culture medium composition
Published in PloS one (22-02-2017)“…Rodent organotypic hippocampal cultures spontaneously develop epileptiform activity after approximately 2 weeks in vitro and are increasingly used as a model…”
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13
Knee Angle Estimation with Dynamic Calibration Using Inertial Measurement Units for Running
Published in Sensors (Basel, Switzerland) (01-01-2024)“…The knee flexion angle is an important measurement for studies of the human gait. Running is a common activity with a high risk of knee injury. Studying the…”
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Extra-pair paternity drives plumage colour elaboration in male passerines
Published in PloS one (22-08-2022)“…The elaborate ornamental plumage displayed by birds has largely been attributed to sexual selection, whereby the greater success of ornamented males in…”
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Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice
Published in PloS one (21-07-2016)“…Ovarian steroids, estradiol and progesterone, play central roles in regulating female reproduction by acting as both positive and negative regulators of…”
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Global patterns of plumage color evolution in island-living passeriform birds
Published in PloS one (15-12-2023)“…Island environments have the potential to change evolutionary trajectories of morphological traits in species relative to their mainland counterparts due to…”
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The adventitia: a progenitor cell niche for the vessel wall
Published in Cells, tissues, organs (01-01-2012)“…Recent observations suggest that the adventitial layer of blood vessels exhibits properties resembling a stem/progenitor cell niche. Progenitor cells have been…”
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Developmental programming: Impact of fetal exposure to endocrine-disrupting chemicals on gonadotropin-releasing hormone and estrogen receptor mRNA in sheep hypothalamus
Published in Toxicology and applied pharmacology (01-09-2010)“…Bisphenol-A (BPA) and methoxychlor (MXC), two endocrine-disrupting chemicals (EDCs) with estrogenic and antiandrogenic effects, disrupt the reproductive…”
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Riparian cottonwood mortality following compound impacts from river water withdrawal and hydroclimatic variation
Published in Ecohydrology (01-09-2023)“…Originating in Glacier Park, Montana, the transboundary St. Mary River has provided a focus for international water sharing for a century. It was dammed and…”
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Biocompatibility of poly(ethylene glycol)-based hydrogels in the brain: An analysis of the glial response across space and time
Published in Journal of biomedical materials research. Part A (01-10-2010)“…Poly(ethylene glycol) or PEG‐based hydrogels provide a useful methodology for tissue engineering and the controlled‐release of drugs within the central nervous…”
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