Search Results - "MAHMOOD, Radma"
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Modulation of basal cell fate during productive and transforming HPV‐16 infection is mediated by progressive E6‐driven depletion of Notch
Published in The Journal of pathology (01-08-2017)“…In stratified epithelia such as the epidermis, homeostasis is maintained by the proliferation of cells in the lower epithelial layers and the concomitant loss…”
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Human papillomavirus type 16 causes a defined subset of conjunctival in situ squamous cell carcinomas
Published in Modern pathology (01-01-2020)“…Squamous cell carcinoma of the conjunctiva is associated with a number of risk factors, including HIV infection, iatrogenic immunosuppression and atopy. In…”
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HPV16 and 18 genome amplification show different E4-dependence, with 16E4 enhancing E1 nuclear accumulation and replicative efficiency via its cell cycle arrest and kinase activation functions
Published in PLoS pathogens (01-03-2017)“…To clarify E1^E4's role during high-risk HPV infection, the E4 proteins of HPV16 and 18 were compared side by side using an isogenic keratinocyte…”
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Correction to: Human papillomavirus type 16 causes a defined subset of conjunctival in situ squamous cell carcinomas
Published in Modern pathology (01-02-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration
Published in PLoS genetics (10-05-2018)“…Down Syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and results in a spectrum of phenotypes including learning and memory deficits, and motor…”
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TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology
Published in PLoS pathogens (01-08-2016)“…Persistent TH2 cytokine responses following chronic helminth infections can often lead to the development of tissue pathology and fibrotic scarring. Despite a…”
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Fgf3 and Fgf8 are required together for formation of the otic placode and vesicle
Published in Development (Cambridge) (01-05-2002)“…Fgf3 has long been implicated in otic placode induction and early development of the otocyst; however, the results of experiments in mouse and chick embryos to…”
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ErbB3-dependent motility and intravasation in breast cancer metastasis
Published in Cancer research (Chicago, Ill.) (01-02-2006)“…A better understanding of how epidermal growth factor receptor family members (ErbBs) contribute to metastasis is important for evaluating ErbB-directed…”
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Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain
Published in Development (Cambridge) (01-03-1999)“…Experiments involving tissue recombinations have implicated both early vertical and later planar signals in the specification and polarisation of the midbrain…”
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A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth
Published in Current biology (01-07-1995)“…Background: The outgrowth of the vertebrate limb bud is the result of a reciprocal interaction between the mesenchyme and a specialized region of the ectoderm,…”
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Multiple roles for FGF-3 during cranial neural development in the chicken
Published in Development (Cambridge) (01-05-1995)“…FGF-3 has been implicated in the development of the hindbrain and otocyst in vertebrate embryos. Since the chicken embryo offers a favourable system in which…”
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The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly
Published in Developmental biology (15-08-2016)“…Adprhl1, a member of the ADP-ribosylhydrolase protein family, is expressed exclusively in the developing heart of all vertebrates. In the amphibian Xenopus…”
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Phenotypic Modulation of Skeletal Muscle Fibers in LPIN1-Deficient Lipodystrophic (fld) Mice
Published in Veterinary pathology (01-03-2019)“…Lipin-1 (Lpin1)–deficient lipodystrophic mice have scant and immature adipocytes and develop transient fatty liver early in life. Unlike normal mice, these…”
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Colonic Tumorigenesis in BubR1+/-ApcMin/+Compound Mutant Mice Is Linked to Premature Separation of Sister Chromatids and Enhanced Genomic Instability
Published in Proceedings of the National Academy of Sciences - PNAS (22-03-2005)“…Faithful chromosome segregation is essential for the maintenance of genetic stability during cell division and it is at least partly monitored by the spindle…”
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Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice
Published in Molecular and Cellular Biology (01-09-2004)“…ERRATUM ( vol. 25 , p. 523 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency
Published in Cancer research (Chicago, Ill.) (15-01-2004)“…A compromised spindle checkpoint is thought to play a key role in genetic instability that predisposes cells to malignant transformation. Loss of function…”
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TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control T.sub.H2-Mediated Immunopathology
Published in PLoS pathogens (03-08-2016)“…Persistent T.sub.H 2 cytokine responses following chronic helminth infections can often lead to the development of tissue pathology and fibrotic scarring…”
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Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia
Published in Cancer research (Chicago, Ill.) (01-11-2006)“…Nkx2.8, a homeodomain transcription factor, has been characterized in liver cancer and in the developing central nervous system. We now show that this factor…”
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TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control T H 2-Mediated Immunopathology
Published in PLoS pathogens (01-08-2016)“…Persistent TH2 cytokine responses following chronic helminth infections can often lead to the development of tissue pathology and fibrotic scarring. Despite a…”
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