Search Results - "MAHBOOBI, S"

HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer by Stojanovic, N, Hassan, Z, Wirth, M, Wenzel, P, Beyer, M, Schäfer, C, Brand, P, Kroemer, A, Stauber, R H, Schmid, R M, Arlt, A, Sellmer, A, Mahboobi, S, Rad, R, Reichert, M, Saur, D, Krämer, O H, Schneider, G

“…Mutation of p53 is a frequent genetic lesion in pancreatic cancer being an unmet clinical challenge. Mutants of p53 have lost the tumour-suppressive functions…”
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Qualitative study of nanocluster positioning process: Planar molecular dynamics simulations by Mahboobi, S.H., Meghdari, A., Jalili, N., Amiri, F.

“…One of the key factors in the assembly of nanoclusters is the precise positioning of them by a manipulation system. Currently the size of clusters used as…”
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Precise positioning and assembly of metallic nanoclusters as building blocks of nanostructures: A molecular dynamics study by Mahboobi, S.H., Meghdari, A., Jalili, N., Amiri, F.

“…Molecular dynamics simulations are used to study the manipulation of metallic nanoclusters. These particles are assumed as potential building blocks for…”
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Synthetic 2-Aroylindole Derivatives as a New Class of Potent Tubulin-Inhibitory, Antimitotic Agents by Mahboobi, Siavosh, Pongratz, Herwig, Hufsky, Harald, Hockemeyer, Jörg, Frieser, Markus, Lyssenko, Alexei, Paper, Dietrich H, Bürgermeister, Jutta, Böhmer, Frank-D, Fiebig, Heinz-Herbert, Burger, Angelika M, Baasner, Silke, Beckers, Thomas

“…A new class of simple synthetic antimitotic compounds based on 2-aroylindoles was discovered. (5-Methoxy-1H-2-indolyl)-phenylmethanone (1) as well as analogous…”
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Observer-based control design for three well-known chaotic systems by Mahboobi, S.H., Shahrokhi, M., Pishkenari, H.N.

“…In this paper, a singularity-free approach is proposed for controlling three well-known chaotic systems namely Lorenz, Chen and Lu. The control design…”
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A Novel Approach for Optimal Design of a Rover Mechanism by Meghdari, A, Pishkenari, H N, Gaskarimahalle, A L, Mahboobi, S H, Karimi, R

“…This article presents an overview of the mechanical design and fabrication of a Rescue Robot (CEDRA) for operation in unstructured environments. In order to…”
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Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3 by TELLER, S, KRÄMER, D, SERVE, H, BÖHMER, F-D, BÖHMER, S-A, TSE, K. F, SMALL, D, MAHBOOBI, S, WALLRAPP, C, BECKERS, T, KRATZ-ALBERS, K, SCHWÄBLE, J

“…Aberrant expression and activating mutations of the class III receptor tyrosine kinase Flt3 (Flk-2, STK-1) have been linked to poor prognosis in acute myeloid…”
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Effect of laryngoscopy and tracheal intubation on pulse pressure and influence of age on this response by KHAN, F. A, MAHBOOBI, S. K

“…The study objective was to measure the change in pulse pressure associated with laryngoscopy and tracheal intubation and to relate these changes to trends in…”
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Computational Study of Binding Between DDX3 and Hiv-1 MRNA Nucleocytoplasmic Export Complex by Mahboobi, S. Hanif

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X-ray Crystal Structure of Woodinine and Conformational Analysis by Semiempirical and 1H-NMR Methods by Mahboobi, S, Dove, S, Bednarski, P. J, Kuhr, S, Burgemeister, T, Schollmeyer, D

“…The molecular structure of (−)-woodinine (1), a carboline-based alkaloid with antibacterial and antimycobacterial activities, was investigated by X-ray…”
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Manipulation of biomolecules: A molecular dynamics study by Mahdjour Firouzi, M.A., Nejat Pishkenari, H., Mahboobi, S.H., Meghdari, A.

“…With the rapid progression of bionanorobotics, manipulation of nano-scale biosamples is becoming increasingly attractive for different biological purposes…”
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Molecular dynamics simulation of manipulation of metallic nanoclusters on double-layer substrates by Mahboobi, S.H., Meghdari, A., Jalili, N., Amiri, F.

“…Molecular dynamics simulations are carried out to investigate the manipulation of metallic clusters on double-layer surfaces. The system parts are made of…”
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3-Bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives as new lead compounds for antibacterially active substances by Mahboobi, Siavosh, Eichhorn, Emerich, Popp, Alfred, Sellmer, Andreas, Elz, Sigurd, Möllmann, Ute

“…A number of new compounds containing 3-bromo-2,5-dihydro-1H-2,5-pyrroledione and indole substructures were found to have antibacterial activity against…”
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A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571 by Böhmer, Frank D, Karagyozov, Luchezar, Uecker, Andrea, Serve, Hubert, Botzki, Alexander, Mahboobi, Siavosh, Dove, Stefan

“…The tyrosine kinase inhibitor STI-571 potently blocks BCR-Abl, platelet-derived growth factor (PDGF) α- and β-receptors, and c-Kit kinase activity. Flt3, a…”
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Adaptive regulation and set-point tracking of the Lorenz attractor by Pishkenari, H.N., Shahrokhi, M., Mahboobi, S.H.

“…In this paper, an approach is proposed for controlling the uncertain Lorenz system. Based on an identification technique, a controller is designed that…”
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Chimeric tyrosine kinase-HDAC inhibitors as antiproliferative agents by Uecker, Andrea, Sicker, Marit, Beckers, Thomas, Mahboobi, Siavosh, Hägerstrand, Daniel, Östman, Arne, Böhmer, Frank-D

“…Combined treatment with tyrosine kinase inhibitors (TKi) and additional drugs is emerging as a promising strategy for cancer therapy. TKi and…”
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2-Aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors by BECKERS, Thomas, REISSMANN, Thomas, MAHBOOBI, Siavosh, SCHMIDT, Mathias, BURGER, Angelika M, FIEBIG, Heinz H, VANHOEFER, Udo, PONGRATZ, Herwig, HUFSKY, Harald, HOCKEMEYER, Jörg, FRIESER, Markus

“…2-Aroylindoles with 5-methoxy-1H-2-indolyl-phenylmethanone (D-64131) as the lead structure were discovered as a new class of synthetic, small molecule tubulin…”
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Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines by MAHBOOBI, Siavosh, SELLMER, Andreas, EICHHORN, Emerich, BECKERS, Thomas, FIEBIG, Heinz-Herbert, KELTER, Gerhard

“…Synthesis and cytotoxic activity of a series of 2-acyl-1H-indole-4,7-diones on human cancer cell lines are described. Due to close structural relationship to…”
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Synthesis of Pyrrolidin-2-ones and of Staurosporine Aglycon (K-252c) by Intermolecular Michael Reaction by Mahboobi, Siavosh, Eibler, Ernst, Koller, Markus, Kumar KC, Sunil, Popp, Alfred, Schollmeyer, Dieter

“…Indolo[2,3-a]pyrrolo[3,4-c]carbazoles were isolated from nature, e.g., from low plants, especially fungi, as structurally rare natural substances. Responsible…”
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Homoarcyriaflavin:  Synthesis of Ring-Expanded Arcyriaflavin Analogues by Mahboobi, Siavosh, Burgemeister, Thomas, Dove, Stefan, Kuhr, Sabine, Popp, Alfred

“…The construction of the ring-expanded carbazole system, forming arcyriaflavin homologues, is efficiently accomplished by the reaction of 2,2‘-bridged…”
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