Search Results - "MAGUIRE, T"
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A multi-star synchronous machine model for real-time digital simulation and its applications
Published in Electric power systems research (01-08-2021)“…•Simulation of multi-star machines supports renewable energy and electric ship applications.•Analysis in rotor frame of reference is important for poly-phase…”
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A TLR5 mono-agonist restores inhibited immune responses to Streptococcus pneumoniae during influenza virus infection in human monocytes
Published in PloS one (13-10-2021)“…Influenza A virus (IAV) predisposes individuals to often more severe secondary bacterial infections with Streptococcus pneumonia (S. pneumoniae). The outcomes…”
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Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment
Published in Nature communications (19-05-2022)“…Calcium entering mitochondria potently stimulates ATP synthesis. Increases in calcium preserve energy synthesis in cardiomyopathies caused by mitochondrial…”
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sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1⁺ smooth muscle progenitor cells
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2008)“…We characterize a sonic hedgehog (Shh) signaling domain restricted to the adventitial layer of artery wall that supports resident Sca1-positive vascular…”
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Community-based headache management
Published in International journal of clinical practice. Supplement (01-05-2015)“…Tension-type headache (TTH) - also known as 'regular' or 'ordinary' headache - is extremely common. The key symptom is a tight band or pressing pain felt on…”
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Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human
Published in Biochemical pharmacology (15-09-2009)“…Integral to the discovery of new pharmaceutical entities is the ability to predict in vivo pharmacokinetic parameters from early stage in vitro data generated…”
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Water and sediment as sources of phosphate in aquatic ecosystems: The Detroit River and its role in the Laurentian Great Lakes
Published in The Science of the total environment (10-01-2019)“…Eutrophication of freshwater ecosystems and harmful algal blooms (HABs) are an ongoing concern affecting water quality in the Great Lakes watershed of North…”
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Liver Defatting: An Alternative Approach to Enable Steatotic Liver Transplantation
Published in American journal of transplantation (01-12-2012)“…Macrovesicular steatosis in greater than 30% of hepatocytes is a significant risk factor for primary graft nonfunction due to increased sensitivity to ischemia…”
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The history and geographic distribution of a KCNQ1 atrial fibrillation risk allele
Published in Nature communications (08-11-2021)“…The genetic architecture of atrial fibrillation (AF) encompasses low impact, common genetic variants and high impact, rare variants. Here, we characterize a…”
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Comparative analysis of genetic diversity in the mangrove species Avicennia marina (Forsk.) Vierh. (Avicenniaceae) detected by AFLPs and SSRs
Published in Theoretical and applied genetics (01-02-2002)“…Avicennia marina is an important mangrove species with a wide geographical and climatic distribution which suggests that large amounts of genetic diversity are…”
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Seclusion reduction in a forensic mental health setting
Published in Journal of psychiatric and mental health nursing (01-03-2012)“…Accessible summary • Seclusion has become a contentious practice and, internationally, initiatives have commenced to reduce or eliminate its use. • In…”
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Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-γ responses to pneumococcus in vitro in human monocytes
Published in PloS one (07-09-2018)“…Influenza virus is highly contagious and poses substantial public health problems due to its strong association with morbidity and mortality. Approximately…”
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Ibuprofen: a model medicine for self-care of common conditions
Published in International journal of clinical practice. Supplement (01-01-2013)“…The expansion and development of the self-care agenda across Europe and beyond has the potential to realise huge efficiencies for national health services…”
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Author Correction: Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment
Published in Nature communications (20-06-2022)Get full text
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Loss of MicroRNAs in Neural Crest Leads to Cardiovascular Syndromes Resembling Human Congenital Heart Defects
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2010)“…OBJECTIVE—Congenital heart defects represent the most common human birth defects. Even though the genetic cause of these syndromes has been linked to candidate…”
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Do recovery outcome measures improve clinical practice? A linguistic analysis of the impact of the Hope, Agency and Opportunity measure in community mental health teams
Published in Perspectives in Public Health (01-03-2020)“…Aims: Recovery approaches are identified as the overarching framework for improving mental health services for people with severe and enduring conditions…”
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Genome-wide analysis reveals the unique stem cell identity of human amniocytes
Published in PloS one (10-01-2013)“…Human amniotic fluid contains cells that potentially have important stem cell characteristics, yet the programs controlling their developmental potency are…”
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Design and application of microfluidic systems for in vitro pharmacokinetic evaluation of drug candidates
Published in Current drug metabolism (01-12-2009)“…One of the fundamental challenges facing the development of new chemical entities within the pharmaceutical industry is the extrapolation of key in vivo…”
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14-3-3ε Plays a Role in Cardiac Ventricular Compaction by Regulating the Cardiomyocyte Cell Cycle
Published in Molecular and Cellular Biology (01-12-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Physiologically based pharmacokinetic models: integration of in silico approaches with micro cell culture analogues
Published in Current drug metabolism (01-07-2012)“…There is a large emphasis within the pharmaceutical industry to provide tools that will allow early research and development groups to better predict dose…”
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