Search Results - "MAGNUSSON, P"

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse by Magnusson, Jens P., Göritz, Christian, Tatarishvili, Jemal, Dias, David O., Smith, Emma M. K., Lindvall, Olle, Kokaia, Zaal, Frisén, Jonas

“…Neurogenesis is restricted in the adult mammalian brain; most neurons are neither exchanged during normal life nor replaced in pathological situations. We…”
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Heritability and confirmation of genetic association studies for childhood asthma in twins by Ullemar, V., Magnusson, P. K. E., Lundholm, C., Zettergren, A., Melén, E., Lichtenstein, P., Almqvist, C.

“…Background Although the genetics of asthma has been extensively studied using both quantitative and molecular genetic analysis methods, both approaches lack…”
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Looking into the past – the reaction of three grouse species to climate change over the last million years using whole genome sequences by Kozma, Radoslav, Melsted, Páll, Magnússon, Kristinn P, Höglund, Jacob

“…Tracking past population fluctuations can give insight into current levels of genetic variation present within species. Analysing population dynamics over…”
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The genetic influence on diverticular disease - a twin study by Granlund, J., Svensson, T., Olén, O., Hjern, F., Pedersen, N. L., Magnusson, P. K. E., Thelin Schmidt, P.

“…Summary Background The contribution of hereditary factors to the development of diverticular disease (DD) of the colon is unknown. Prevalence and location of…”
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Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder by Bergen, S E, O'Dushlaine, C T, Ripke, S, Lee, P H, Ruderfer, D M, Akterin, S, Moran, J L, Chambert, K D, Handsaker, R E, Backlund, L, Ösby, U, McCarroll, S, Landen, M, Scolnick, E M, Magnusson, P K E, Lichtenstein, P, Hultman, C M, Purcell, S M, Sklar, P, Sullivan, P F

“…Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable psychiatric disorders with overlapping susceptibility loci and symptomatology. We conducted…”
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Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations by Zhang, Daniel Y, Dmello, Crismita, Chen, Li, Arrieta, Victor A, Gonzalez-Buendia, Edgar, Kane, J Robert, Magnusson, Lisa P, Baran, Aneta, James, C David, Horbinski, Craig, Carpentier, Alexandre, Desseaux, Carole, Canney, Michael, Muzzio, Miguel, Stupp, Roger, Sonabend, Adam M

“…Paclitaxel shows little benefit in the treatment of glioma due to poor penetration across the blood-brain barrier (BBB). Low-intensity pulsed ultrasound (LIPU)…”
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SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space by Beter, M., Abdollahzadeh, A., Pulkkinen, H. H., Huang, H., Orsenigo, F., Magnusson, P. U., Ylä-Herttuala, S., Tohka, J., Laakkonen, J. P.

“…Three-dimensional image analyses are required to improve the understanding of the regulation of blood vessel formation and heterogeneity. Currently,…”
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Copy number variation in schizophrenia in Sweden by Szatkiewicz, J P, O'Dushlaine, C, Chen, G, Chambert, K, Moran, J L, Neale, B M, Fromer, M, Ruderfer, D, Akterin, S, Bergen, S E, Kähler, A, Magnusson, P K E, Kim, Y, Crowley, J J, Rees, E, Kirov, G, O'Donovan, M C, Owen, M J, Walters, J, Scolnick, E, Sklar, P, Purcell, S, Hultman, C M, McCarroll, S A, Sullivan, P F

“…Schizophrenia (SCZ) is a highly heritable neuropsychiatric disorder of complex genetic etiology. Previous genome-wide surveys have revealed a greater burden of…”
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Evaluation of arrhythmias using an insertable cardiac monitor in patients with hypertrophic cardiomyopathy by Magnusson, P., Mörner, Stellan

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The timed up and go test predicts fracture risk in older women independently of clinical risk factors and bone mineral density by Larsson, B. A. M., Johansson, L., Johansson, H., Axelsson, K. F., Harvey, N., Vandenput, L., Magnusson, P., McCloskey, E., Liu, E., Kanis, J. A., Sundh, D., Lorentzon, M.

“…Summary The timed up and go (TUG) test measures physical performance and predicts falls in the elderly. In older women, TUG time predicts the risk of major…”
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Multifactorial analysis of changes in body mass index across the adult life course: a study with 65 years of follow-up by Dahl, A K, Reynolds, C A, Fall, T, Magnusson, P K E, Pedersen, N L

“…Background: Although the negative consequences on health of being obese are well known, most adults gain weight across the lifespan. The general increase in…”
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Clinical assessment of hip strength using a hand-held dynamometer is reliable by Thorborg, K., Petersen, J., Magnusson, S. P., Hölmich, P.

“…Hip strength assessment plays an important role in the clinical examination of the hip and groin region. The primary aim of this study was to examine the…”
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Effects of aging on human skeletal muscle after immobilization and retraining by Suetta, C, Hvid, L. G, Justesen, L, Christensen, U, Neergaard, K, Simonsen, L, Ortenblad, N, Magnusson, S. P, Kjaer, M, Aagaard, P

“…1 Institute of Sports Medicine and Centre of Healthy Aging, Faculty of Health Science, University of Copenhagen, Bispebjerg Hospital; ; 2 Institute of Sports…”
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An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise by Ziegler, A. K., Damgaard, A., Mackey, A. L., Schjerling, P., Magnusson, P., Olesen, A. T., Kjaer, M., Scheele, C.

“…Visceral adipose tissue is an immunogenic tissue, which turns detrimental during obesity by activation of proinflammatory macrophages. During aging, chronic…”
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Enhanced Cas12a multi-gene regulation using a CRISPR array separator by Magnusson, Jens P, Rios, Antonio Ray, Wu, Lingling, Qi, Lei S

“…The type V-A Cas12a protein can process its CRISPR array, a feature useful for multiplexed gene editing and regulation. However, CRISPR arrays often exhibit…”
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Group sequential enrichment design incorporating subgroup selection by Magnusson, Baldur P., Turnbull, Bruce W.

“…An important component of clinical trials in drug development is the analysis of treatment efficacy in patient subgroups (subpopulations). Because of concerns…”
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Mechanical properties and collagen cross-linking of the patellar tendon in old and young men by Couppe, C, Hansen, P, Kongsgaard, M, Kovanen, V, Suetta, C, Aagaard, P, Kjaer, M, Magnusson, S. P

“…1 Institute of Sports Medicine, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark; 2…”
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Activation of a neural stem cell transcriptional program in parenchymal astrocytes by Magnusson, Jens P, Zamboni, Margherita, Santopolo, Giuseppe, Mold, Jeff E, Barrientos-Somarribas, Mauricio, Talavera-Lopez, Carlos, Andersson, Björn, Frisén, Jonas

“…Adult neural stem cells, located in discrete brain regions, generate new neurons throughout life. These stem cells are specialized astrocytes, but astrocytes…”
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A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder by Sellgren, C M, Kegel, M E, Bergen, S E, Ekman, C J, Olsson, S, Larsson, M, Vawter, M P, Backlund, L, Sullivan, P F, Sklar, P, Smoller, J W, Magnusson, P K E, Hultman, C M, Walther-Jallow, L, Svensson, C I, Lichtenstein, P, Schalling, M, Engberg, G, Erhardt, S, Landén, M

“…Elevated cerebrospinal fluid (CSF) levels of the glia-derived N -methyl- D -aspartic acid receptor antagonist kynurenic acid (KYNA) have consistently been…”
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Integrated production of polyhydroxyalkanoates (PHAs) with municipal wastewater and sludge treatment at pilot scale by Morgan-Sagastume, F, Hjort, M, Cirne, D, Gérardin, F, Lacroix, S, Gaval, G, Karabegovic, L, Alexandersson, T, Johansson, P, Karlsson, A, Bengtsson, S, Arcos-Hernández, M V, Magnusson, P, Werker, A

“…A pilot-scale process was operated over 22 months at the Brussels North Wastewater Treatment Plant (WWTP) in order to evaluate polyhydroxyalkanoate (PHA)…”
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