Search Results - "MAGEE, A. I"

Retargeting of cytosolic proteins to the plasma membrane by the Lck protein tyrosine kinase dual acylation motif by Zlatkine, P, Mehul, B, Magee, A I

“…Several members of the Src family of protein tyrosine kinases have a N-terminal dual acylation motif which specifies their myristoylation and S-acylation…”
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The cadherin superfamily by Angst, B D, Marcozzi, C, Magee, A I

“…The poster provides an overview of the cadherin superfamily, depicting representative molecules for several subfamilies, and displaying the plethora of…”
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Remodeling of Gap Junctional Coupling in Hypertrophied Right Ventricles of Rats With Monocrotaline-Induced Pulmonary Hypertension by Uzzaman, Mahmud, Honjo, Haruo, Takagishi, Yoshiko, Emdad, Luni, Magee, Anthony I, Severs, Nicholas J, Kodama, Itsuo

“…The present study investigates the remodeling of gap junctional organization in relation to changes in anisotropic conduction properties in hypertrophied right…”
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Nomenclature of the Desmosomal Cadherins by Buxton, R. S., Cowin, P., Franke, W. W., Garrod, D. R., Green, K. J., King, I. A., Koch, P. J., Magee, A. I., Rees, D. A., Stanley, J. R., Steinberg, M. S.

“…The results of cDNA cloning and sequencing have established that the major glycoproteins of the desmosome type of cell-cell junctions are members of the…”
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Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif by Koegl, M, Zlatkine, P, Ley, S C, Courtneidge, S A, Magee, A I

“…We have recently identified a novel N-terminal cysteine-containing motif which specifies the palmitoylation of several G-protein alpha-subunits [Parenti,…”
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All ras proteins are polyisoprenylated but only some are palmitoylated by Hancock, J F, Magee, A I, Childs, J E, Marshall, C J

“…The C-terminal CAAX motif of the yeast mating factors is modified by proteolysis to remove the three terminal amino acids (-AAX) leaving a C-terminal cysteine…”
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Dissociated Spatial Patterning of Gap Junctions and Cell Adhesion Junctions During Postnatal Differentiation of Ventricular Myocardium by Angst, Brigitt D, Khan, Laeeq U.R, Severs, Nicholas J, Whitely, Kate, Rothery, Stephen, Thompson, Robert P, Magee, Anthony I, Gourdie, Robert G

“…Nonuniformity in the spatial patterning of gap junctions between heart muscle cells is now recognized as an important determinant of electromechanical function…”
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A novel N-terminal motif for palmitoylation of G-protein α subunits by PARENTI, M, VIGANO, M. A, NEWMAN, C. M. H, MILLIGAN, G, MAGEE, A. I

“…We have examined the post-translational processing of G alpha subunits expressed endogenously in rat PC12 and NG108-15 rat/mouse hybrid cells, and after…”
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Dynamic fatty acylation of p21N‐ras by Magee, A. I., Gutierrez, L., McKay, I. A., Marshall, C. J., Hall, A.

“…To study the acylation of p21N‐ras with palmitic acid we have used cells which express the human N‐ras gene to high levels under control of the…”
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The cadherin superfamily: diversity in form and function by Angst, B D, Marcozzi, C, Magee, A I

“…Over recent years cadherins have emerged as a growing superfamily of molecules, and a complex picture of their structure and their biological functions is…”
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Aggregation of Lipid Rafts Accompanies Signaling Via the T Cell Antigen Receptor by Janes, Peter W., Ley, Steven C., Magee, Anthony I.

“…The role of lipid rafts in T cell antigen receptor (TCR) signaling was investigated using fluorescence microscopy. Lipid rafts labeled with cholera toxin B…”
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High speed optically sectioned fluorescence lifetime imaging permits study of live cell signaling events by Grant, David M, McGinty, J, McGhee, E J, Bunney, T D, Owen, D M, Talbot, C B, Zhang, W, Kumar, S, Munro, I, Lanigan, P M, Kennedy, G T, Dunsby, C, Magee, A I, Courtney, P, Katan, M, Neil, M A A, French, P M W

“…We present a time domain optically sectioned fluorescence lifetime imaging (FLIM) microscope developed for high-speed live cell imaging. This single photon…”
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Posttranslational processing of the ras superfamily of small GTP-binding proteins by Newman, C M, Magee, A I

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lipid modification of proteins and its relevance to protein targeting by MAGEE, A. I

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The role of lipid rafts in T cell antigen receptor (TCR) signalling by Janes, Peter W., Ley, Steven C., Magee, Anthony I., Kabouridis, Panagiotis S.

“…Copyright 2000 Academic PressPlasma membranes of many cell types contain domains enriched in specific lipids and cholesterol, called lipid rafts. In T…”
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Desmosomal Glycoprotein DGI, a Component of Intercellular Desmosome Junctions, is Related to the Cadherin Family of Cell Adhesion Molecules by Wheeler, G. N., Parker, A. E., Thomas, C. L., Ataliotis, P., Poynter, D., Arnemann, J., Rutman, A. J., Pidsley, S. C., Watt, F. M., Rees, D. A., Buxton, R. S., Magee, A. I.

“…Among the variety of specialized intercellular junctions, those of the adherens type have the most obvious association with cytoskeletal elements. This may be…”
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Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing by PARKER, A. E, WHEELER, G. N, ARNEMANN, J, PIDSLEY, S. C, ATALIOTIS, P, THOMAS, C. L, REES, D. A, MAGEE, A. I, BUXTON, R. S

“…We have cloned the human genes coding for desmosomal glycoproteins DGII and DGIII, found in desmosomal cell junctions, and sequencing shows that they are…”
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Post-translational processing of Schizosaccharomyces pombe YPT proteins by NEWMAN, C. M. H, GIANNAKOUROS, T, HANCOCK, J. F, FAWELL, E. H, ARMSTRONG, J, MAGEE, A. I

“…ras proteins are post-translationally processed at their carboxyl-terminal CAAX motif by a triplet of modifications: prenylation of C with farnesyl,…”
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S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes by Kabouridis, Panagiotis S., Magee, Anthony I., Ley, Steven C.

“…LCK is a non‐receptor protein tyrosine kinase required for signal transduction via the T‐cell antigen receptor (TCR). LCK N‐terminus is S‐acylated on Cys3 and…”
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Two classes of fatty acid acylated proteins exist in eukaryotic cells by Magee, A.I., Courtneidge, S.A.

“…Labelling of cultured cells with [3H]palmitic and [3H]myristic acids demonstrates that each of these fatty acids modifies a substantially different subset of…”
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