Search Results - "MAGALHAES, Geraldo S"
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Design and Production of a Recombinant Hybrid Toxin to Raise Protective Antibodies Against Loxosceles Spider Venom
Published in Toxins (12-02-2019)“…Human accidents with spiders of the genus Loxosceles are an important health problem affecting thousands of people worldwide. Patients evolve to severe local…”
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Gene expression of inflammatory mediators induced by jararhagin on endothelial cells
Published in Toxicon (Oxford) (01-11-2012)“…Snake venom metalloproteinases (SVMP) are abundant toxins in venoms of viper snakes and play a relevant role in the complex and multifactorial tissue damage…”
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Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to α2β1 integrin and collagen
Published in Toxicon (Oxford) (01-06-2010)Get full text
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Insularin, a disintegrin from Bothrops insularis venom: Inhibition of platelet aggregation and endothelial cell adhesion by the native and recombinant GST-insularin proteins
Published in Toxicon (Oxford) (01-01-2011)“…Insularin (INS) was obtained from Bothrops insularis venom by reversed-phase highperformance liquid chromatography using a C18 column and characterized as a…”
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Recombinant Phospholipase D from Loxosceles gaucho Binds to Platelets and Promotes Phosphatidylserine Exposure
Published in Toxins (13-06-2017)“…Spider envenomation, from the genus , is frequently reported as a cause of necrotic lesions in humans around the world. Among the many components found in the…”
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When spider and snake get along: Fusion of a snake disintegrin with a spider phospholipase D to explore their synergistic effects on a tumor cell
Published in Toxicon (Oxford) (01-10-2019)“…Venoms of spiders and snakes contain toxins extremely active and, thus, provide a natural source for the development of new biotechnological tools. Among the…”
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Erratum to: A novel ELISA for diagnosis of Glanzmann’s thrombasthenia and the heterozygote carriers
Published in Annals of hematology (01-07-2015)“…Erratum to: Annals of Hematology 91(6): 917–921. DOI 10.1007/s00277-011-1390-1 . The authors inadvertently omitted 2 fellow authors from the author list: Dr…”
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Unraveling the Processing and Activation of Snake Venom Metalloproteinases
Published in Journal of proteome research (03-07-2014)“…Snake venom metalloproteinases (SVMPs) are zinc-dependent enzymes responsible for most symptoms of human envenoming. Like matrix metalloproteinases (MMPs) and…”
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Toxin Fused with SUMO Tag: A New Expression Vector Strategy to Obtain Recombinant Venom Toxins with Easy Tag Removal inside the Bacteria
Published in Toxins (27-02-2017)“…Many animal toxins may target the same molecules that need to be controlled in certain pathologies; therefore, some toxins have led to the formulation of drugs…”
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Cloning, expression and characterization of a phospholipase D from Loxosceles gaucho venom gland
Published in Biochimie (01-09-2013)“…Loxosceles venom comprises a mixture of diverse toxins that induces intense local inflammatory reaction, dermonecrotic injury, platelet aggregation, hemolytic…”
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Synthesis of Human Bone Morphogenetic Protein-2 (hBMP-2) in E. coli Periplasmic Space: Its Characterization and Preclinical Testing
Published in Cells (Basel, Switzerland) (14-12-2021)“…Human BMP-2, a homodimeric protein that belongs to the TGF- β family, is a recognized osteoinductor due to its capacity of inducing bone regeneration and…”
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Diversity of metalloproteinases in Bothrops neuwiedi snake venom transcripts: evidences for recombination between different classes of SVMPs
Published in BMC genetics (01-11-2011)“…Snake venom metalloproteinases (SVMPs) are widely distributed in snake venoms and are versatile toxins, targeting many important elements involved in…”
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13
A novel ELISA for diagnosis of Glanzmann’s thrombasthenia and the heterozygote carriers
Published in Annals of hematology (01-06-2012)“…A sensitive and specific sandwich ELISA was developed for the diagnosis of Glanzmann’s thrombasthenia (GT) and the heterozygote carriers of the disease using…”
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14
Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to a2b1 integrin and collagen
Published in Toxicon (Oxford) (01-06-2010)“…SVMPs are multi-domain proteolytic enzymes in which disintegrin-like and cysteine-rich domains bind to cell receptors, plasma or ECM proteins. We have recently…”
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15
A novel human G protein-coupled receptor is over-expressed in prostate cancer
Published in Genetics and molecular research (30-12-2004)“…G protein-coupled receptors (GPCRs) are involved in a large variety of physiological functions. The number of known members that belong to this large family of…”
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16
Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to α 2β 1 integrin and collagen
Published in Toxicon (Oxford) (2010)“…SVMPs are multi-domain proteolytic enzymes in which disintegrin-like and cysteine-rich domains bind to cell receptors, plasma or ECM proteins. We have recently…”
Get full text
Journal Article -
17
Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to alpha2beta1 integrin and collagen
Published in Toxicon (Oxford) (01-06-2010)“…SVMPs are multi-domain proteolytic enzymes in which disintegrin-like and cysteine-rich domains bind to cell receptors, plasma or ECM proteins. We have recently…”
Get full text
Journal Article