Search Results - "MAENG, Sungho"

Rational Design of in Vivo Tau Tangle-Selective Near-Infrared Fluorophores: Expanding the BODIPY Universe by Verwilst, Peter, Kim, Hye-Ri, Seo, Jinho, Sohn, Nak-Won, Cha, Seung-Yun, Kim, Yeongmin, Maeng, Sungho, Shin, Jung-Won, Kwak, Jong Hwan, Kang, Chulhun, Kim, Jong Seung

“…The elucidation of the cause of Alzheimer’s disease remains one of the greatest questions in neurodegenerative research. The lack of highly reliable low-cost…”
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The role of glutamate in mood disorders: results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects by Maeng, Sungho, Zarate, Jr, Carlos A

“…In this article, we first review a study showing that the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine leads to rapid, robust, and relatively…”
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p-Coumaric acid enhances long-term potentiation and recovers scopolamine-induced learning and memory impairments by Kim, Hyun-Bum, Lee, Seok, Hwang, Eun-Sang, Maeng, Sungho, Park, Ji-Ho

“…Due to the improvement of medical level, life expectancy increased. But the increased incidence of cognitive disorders is an emerging social problem. Current…”
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How Can Insulin Resistance Cause Alzheimer's Disease? by Yoon, Ji Hye, Hwang, JooHyun, Son, Sung Un, Choi, Junhyuk, You, Seung-Won, Park, Hyunwoo, Cha, Seung-Yun, Maeng, Sungho

“…Alzheimer's disease (AD) is a neurodegenerative disorder associated with cognitive decline. Despite worldwide efforts to find a cure, no proper treatment has…”
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Subanesthetic ketamine rapidly alters medial prefrontal miRNAs involved in ubiquitin-mediated proteolysis by Choi, Yunjung, Kim, Baeksun, Ham, Suji, Chung, Sooyoung, Maeng, Sungho, Kim, Hye-Sun, Im, Heh-In

“…Ketamine is a dissociative anesthetic and a non-competitive NMDAR antagonist. At subanesthetic dose, ketamine can relieve pain and work as a fast-acting…”
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Umbelliferone Ameliorates Memory Impairment and Enhances Hippocampal Synaptic Plasticity in Scopolamine-Induced Rat Model by Choi, Ga-Young, Kim, Hyun-Bum, Cho, Jae-Min, Sreelatha, Inturu, Lee, In-Seo, Kweon, Hee-Seok, Sul, Sehyun, Kim, Sun Ae, Maeng, Sungho, Park, Ji-Ho

“…Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by memory loss and cognitive decline. Among the suggested pathogenic mechanisms of AD,…”
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Effects of Radix Polygalae on Cognitive Decline and Depression in Estradiol Depletion Mouse Model of Menopause by Han, Gaeul, Choi, Junhyuk, Cha, Seung-Yun, Kim, Byung Il, Kho, Hee Kyung, Jang, Maeng-Jin, Kim, Mi Ae, Maeng, Sungho, Hong, Heeok

“…Postmenopausal syndrome refers to symptoms caused by the gradual decrease in female hormones after mid-40 years. As a target organ of estrogen, decrease in…”
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MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson's Disease by Chung, Young Cheul, Kim, Yoon-Seong, Bok, Eugene, Yune, Tae Young, Maeng, Sungho, Jin, Byung Kwan

“…The present study examined whether matrix metalloproteinase-3 (MMP-3) participates in the loss of dopaminergic (DA) neurons in the nigrostriatal pathway in a…”
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Neuroprotective Properties of Rutin Hydrate against Scopolamine-Induced Deficits in BDNF/TrkB/ERK/CREB/Bcl2 Pathways by Sreelatha, Inturu, Choi, Ga-Young, Lee, In-Seo, Inturu, Omkaram, Lee, Hyun-Sook, Park, Yea-Na, Lee, Cheol-Won, Yang, Inkyou, Maeng, Sungho, Park, Ji-Ho

“…: Alzheimer's disease (AD) is an age-related degenerative brain disorder characterized by a progressive decline in cognitive function and memory. This study…”
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Ginsenoside Rg3 Improves Recovery from Spinal Cord Injury in Rats via Suppression of Neuronal Apoptosis, Pro-Inflammatory Mediators, and Microglial Activation by Kim, Dong-Kyu, Kweon, Ki-Jung, Kim, Pyungsoo, Kim, Hee-Jung, Kim, Sung-Soo, Sohn, Nak-Won, Maeng, Sungho, Shin, Jung-Won

“…Spinal cord injury (SCI) is one of the most devastating medical conditions; however, currently, there are no effective pharmacological interventions for SCI…”
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Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract by Shin, Im-Joon, Son, Sung Un, Park, Hyunwoo, Kim, Yoorim, Park, Sung Hyun, Swanberg, Kelley, Shin, Joo-Yeon, Ha, Sang-Kyu, Cho, Yoonju, Bang, Soo-Yong, Lew, Jae-Hwan, Cho, Seung-Hun, Maeng, Sungho

“…Radix Polygalae (the root of Polygala tenuifolia) is a herb widely used in traditional Asian medicine that is thought to exert a variety of neuropsychiatric…”
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Effect of an extract of Pinus koraiensis leaves, Lycium chinense fruit, and Saururus chinensis (Lour.) Baill. leaves on liver function in excessive drinkers: A randomized, double-blind, placebo-controlled trial by Park, Ju Hyun, Bok, Min Kyung, Kim, Jieun, Maeng, Sungho, Kim, Sung-Hoon, Jung, Ji Hoon, Lee, Hyo-Jung, Lim, Hyunjung

“…[Display omitted] •GGT significantly decreased in the women PLC group compared with the placebo group.•TC, LDL-C, and HDL-C significantly decreased in the PLC…”
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Effect of Sinapic Acid on Scopolamine-Induced Learning and Memory Impairment in SD Rats by Lee, In-Seo, Choi, Ga-Young, Sreelatha, Inturu, Yoon, Ji-Won, Youn, Suk-Hee, Maeng, Sungho, Park, Ji-Ho

“…The seriousness of the diseases caused by aging have recently gained attention. Alzheimer's disease (AD), a chronic neurodegenerative disease, accounts for…”
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Evaluating the Memory Enhancing Effects of Angelica gigas in Mouse Models of Mild Cognitive Impairments by Kim, Minsang, Song, Minah, Oh, Hee-Jin, Hui, Jin, Bae, Woori, Shin, Jihwan, Ji, Sang-Dock, Koh, Young Ho, Suh, Joo Won, Park, Hyunwoo, Maeng, Sungho

“…(1) Background: By 2050, it is estimated that 130 million people will be diagnosed with dementia, and currently approved medicines only slow the progression…”
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Effects of Phenolic-Rich Pinus densiflora Extract on Learning, Memory, and Hippocampal Long-Term Potentiation in Scopolamine-Induced Amnesic Rats by Kim, Kwan Joong, Hwang, Eun-Sang, Kim, Min-Jeong, Rha, Chan-Su, Song, Myoung Chong, Maeng, Sungho, Park, Ji-Ho, Kim, Dae-Ok

“…Alzheimer's disease is the most common type of dementia with cognitive impairment. Various plant-derived phenolics are known to alleviate cognitive impairment…”
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Enzyme Treatment Alters the Anti-Inflammatory Activity of the Water Extract of Wheat Germ In Vitro and In Vivo by Song, Youngju, Jeong, Hee-Young, Lee, Jae-Kang, Choi, Yong-Seok, Kim, Dae-Ok, Jang, Davin, Park, Cheon-Seok, Maeng, Sungho, Kang, Hee

“…Wheat germ is rich in quinones that exist as glycosides. In this study, we used Celluclast 1.5L to release the hydroxyquinones, which turn into benzoquinone,…”
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Anti-Amnesic Effects of Epigallocatechin Gallate on Scopolamine-Induced Learning and Memory Dysfunction in Sprague-Dawley Rats by Kim, Min-Jeong, Hwang, Eun-Sang, Kim, Kwan Joong, Maeng, Sungho, Heo, Ho Jin, Park, Ji-Ho, Kim, Dae-Ok

“…Epigallocatechin gallate (EGCG) is a major flavan-3-ol of green tea polyphenols that exhibits various beneficial health effects, including antioxidant,…”
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Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats by Lee, Seok, Kim, Hyun-Bum, Hwang, Eun-Sang, Kim, Eun-Seok, Kim, Sung-Soo, Jeon, Tae-Dong, Song, Min-Cheol, Lee, Ji-Seung, Chung, Min-Chan, Maeng, Sungho, Park, Ji-Ho

“…Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its…”
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Age-Related Decrease in Stress Responsiveness and Proactive Coping in Male Mice by Oh, Hee-Jin, Song, Minah, Kim, Young Ki, Bae, Jae Ryong, Cha, Seung-Yun, Bae, Ji Young, Kim, Yeongmin, You, Minsu, Lee, Younpyo, Shim, Jieun, Maeng, Sungho

“…Coping is a strategic approach to dealing with stressful situations. Those who use proactive coping strategies tend to accept changes and act before changes…”
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Inhibition of prothrombin kringle-2-induced inflammation by minocycline protects dopaminergic neurons in the substantia nigra in vivo by Nam, Jin Han, Leem, Eunju, Jeon, Min-Tae, Kim, Young-Je, Jung, Un Ju, Choi, Myung-Sook, Maeng, Sungho, Jin, Byung Kwan, Kim, Sang Ryong

“…Prothrombin kringle-2 (pKr-2), a domain of prothrombin, can cause the degeneration of mesencephalic dopaminergic neurons through microglial activation…”
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