Search Results - "MAEDA, TAKAKO"

EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins by Lei, Zili, Maeda, Takako, Tamura, Atsushi, Nakamura, Tetsuya, Yamazaki, Yuji, Shiratori, Hidetaka, Yashiro, Kenta, Tsukita, Sachiko, Hamada, Hiroshi

“…Tight junctions (TJs) connect epithelial cells and form a semipermeable barrier that only allows selective passage of ions and solutes across epithelia. Here…”
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Correction of impaired calmodulin binding to RyR2 as a novel therapy for lethal arrhythmia in the pressure-overloaded heart failure by Kato, Takayoshi, MD, Yamamoto, Takeshi, MD, PhD, Nakamura, Yoshihide, MD, Nanno, Takuma, MD, Fukui, Go, MD, Sufu, Yoko, MD, Hamada, Yoriomi, MD, Maeda, Takako, MD, Nishimura, Shigehiko, MD, Ishiguchi, Hironori, MD, Murakami, Wakako, MD, Fukuda, Masakazu, MD, PhD, Xu, Xiaojuan, MD, PhD, Hino, Akihiro, MD, PhD, Ono, Makoto, MD, PhD, Oda, Tetsuro, MD, PhD, Okuda, Shinichi, MD, PhD, Kobayashi, Shigeki, MD, PhD, Koseki, Noritaka, BS, Kyushiki, Hiroyuki, PhD, Yano, Masafumi, MD, PhD

“…Background Calmodulin (CaM) is a key modulator of the channel gating function of the ryanodine receptor (RyR). Objective The purpose of this study was to…”
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Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters by Nabeshima, Ryo, Nishimura, Osamu, Maeda, Takako, Shimizu, Natsumi, Ide, Takahiro, Yashiro, Kenta, Sakai, Yasuo, Meno, Chikara, Kadota, Mitsutaka, Shiratori, Hidetaka, Kuraku, Shigehiro, Hamada, Hiroshi

“…We have examined the role of , a gene highly expressed in embryonic stem cells, in mouse development. Fam60a interacts with components of the Sin3a-Hdac…”
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Stat3 in Resident Macrophages as a Repressor Protein of Inflammatory Response by Matsukawa, Akihiro, Kudo, Shinji, Maeda, Takako, Numata, Kousuke, Watanabe, Hiroyuki, Takeda, Kiyoshi, Akira, Shizuo, Ito, Takaaki

“…Inflammation is counterbalanced by anti-inflammatory cytokines such as IL-10, in which Stat3 mediates the signaling pathway. In this study, we demonstrate that…”
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Pilot Study on Neonatal Screening for Methylmalonic Acidemia Caused by Defects in the Adenosylcobalamin Synthesis Pathway and Homocystinuria Caused by Defects in Homocysteine Remethylation by Kagawa, Reiko, Tajima, Go, Maeda, Takako, Sakura, Fumiaki, Nakamura-Utsunomiya, Akari, Hara, Keiichi, Nishimura, Yutaka, Yuasa, Miori, Shigematsu, Yosuke, Tanaka, Hiromi, Fujihara, Saki, Yoshii, Chiyoko, Okada, Satoshi

“…Neonatal screening (NS) for methylmalonic acidemia uses propionylcarnitine (C3) as a primary index, which is insufficiently sensitive at detecting…”
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Efficacy and safety of sitagliptin as add-on therapy on glycemic control and blood glucose fluctuation in Japanese type 2 diabetes subjects ongoing with multiple daily insulin injections therapy by Shimoda, Seiya, Iwashita, Shinsuke, Ichimori, Shinji, Matsuo, Yasuto, Goto, Rieko, Maeda, Takako, Matsuo, Tomoko, Sekigami, Taiji, Kawashima, Junji, Kondo, Tatsuya, Matsumura, Takeshi, Motoshima, Hiroyuki, Furukawa, Noboru, Nishida, Kenro, Araki, Eiichi

“…To assess the efficacy and safety of adding sitagliptin, an oral dipeptidyl peptidase-4 inhibitor, in subjects with type 2 diabetes inadequately controlled…”
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Aberrant Inflammation and Lethality to Septic Peritonitis in Mice Lacking STAT3 in Macrophages and Neutrophils by Matsukawa, Akihiro, Takeda, Kiyoshi, Kudo, Shinji, Maeda, Takako, Kagayama, Motoko, Akira, Shizuo

“…Stat3 is a transcription factor mediating anti-inflammatory properties of IL-10. In the present study, we demonstrate a pivotal role of Stat3 expressed in…”
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Effects of Olmesartan, an Angiotensin II Receptor Blocker, on Peripheral Insulin Sensitivity in Japanese Subjects with Type 2 Diabetes and Hypertension by Shimoda, Seiya, Goto, Rieko, Furukawa, Noboru, Tsuruzoe, Kaku, Kawashima, Junji, Iwashita, Shinsuke, Maeda, Takako, Ichimori, Shinji, Ichinose, Kenshi, Nishida, Kenro, Araki, Eiichi

“…Objective Several studies have assessed the efficacy of angiotensin receptor blockers (ARBs) on peripheral insulin sensitivity using the euglycemic…”
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The Effect of Psychological Intervention on Personality Change, Coping, and Psychological Distress of Japanese Primary Breast Cancer Patients by Maeda, Takako, Kurihara, Hiroko, Morishima, Isamu, Munakata, Tsunetsugu

“…The purpose of this study is to estimate the effectiveness of psychological intervention on personality change, enhancing perceived emotional support, and,…”
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Evaluation of a new device for measurement of hemoglobin A1c for Japanese subjects by Shimoda, Seiya, Maeda, Takako, Furukawa, Noboru, Ichinose, Kenshi, Taketa, Kayo, Igata, Motoyuki, Senokuchi, Takafumi, Matsumura, Takeshi, Araki, Eiichi

“…Aim The accuracy of HbA1c values measured by use of a new portable device (A1CNow+) was evaluated by comparison with values measured by high-performance liquid…”
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Multiple infected aortic aneurysms repaired by staged in situ graft replacement by Ando, Yusuke, Kurisu, Kazuhiro, Hisahara, Manabu, Mashiba, Kouichi, Maeda, Takako

“…The development of multiple infected aortic aneurysms is extremely rare, and treatment remains challenging. We report here a 72-year-old man with multiple…”
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Erratum to: Evaluation of a new device for measurement of hemoglobin A1c for Japanese subjects by Shimoda, Seiya, Maeda, Takako, Furukawa, Noboru, Ichinose, Kenshi, Taketa, Kayo, Igata, Motoyuki, Senokuchi, Takafumi, Matsumura, Takeshi, Araki, Eiichi

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Absence of CC chemokine receptor 8 enhances innate immunity during septic peritonitis by Matsukawa, Akihiro, Kudoh, Shinji, Sano, Gen-ichiro, Maeda, Takako, Ito, Takaaki, Lukacs, Nicholas W, Hogaboam, Cory M, Kunkel, Steven L, Lira, Sergio A

“…ABSTRACT An effective clearance of microbes is crucial in host defense during infection. In the present study, we demonstrate that CC chemokine receptor 8…”
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The Effect of Postoperative Symptom Experience, and Personality and Psychosocial Factors on Depression Among Postgastrectomy Patients in Japan by Maeda, Takako, Onuoha, Francis N, Munakata, Tsunetsugu

“…Depression, the most common affective disorder in cancer, has a major impact on quality of life. Various risk factors may interact and affect a cancer…”
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Efficacy and safety of sitagliptin as add-on therapy on glycemic control and blood glucose fluctuation in Japanese type 2 diabetes subjects ongoing with multiple daily insulin injections therapy by Seiya Shimoda, Shinsuke Iwashita, Shinji Ichimori, Yasuto Matsuo, Rieko Goto, Takako Maeda, Tomoko Matsuo, Taiji Sekigami, Junji Kawashima, Tatsuya Kondo, Takeshi Matsumura, Hiroyuki Motoshima, Noboru Furukawa, Kenro Nishida, Eiichi Araki

“…[Abstract.] To assess the efficacy and safety of adding sitagliptin, an oral dipeptidyl peptidase-4 inhibitor, in subjects with type 2 diabetes inadequately…”
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Prevalence and characteristics of transesophageal echocardiography-related esophageal mucosal injury in patients with atrial fibrillation who underwent pulmonary vein isolation by Omuro, Ayumi, Wada, Yasuaki, Yoshiga, Yasuhiro, Okuda, Shinichi, Okamoto, Takeshi, Fukuda, Masakazu, Omuro, Takuya, Maeda, Takako, Kinoshita, Natsu, Okamura, Takayuki, Nishikawa, Jun, Takami, Taro, Tanaka, Nobuaki, Yano, Masafumi

“…Transesophageal echocardiography (TEE) is the gold standard for detecting thrombi in the left atrium (LA) and left atrial appendage (LAA) prior to pulmonary…”
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Longitudinal Measurements of Bone Density in Adolescent Girls and Intervention in Diet by Keiko Minamimae, Takako Maeda, Tsunakiyo Kasagi

“…Ca intake raises bone mineral density (BMD) in adolescence. The present study aimed at improving BMD in adolescent girls by increasing Ca intake from foods,…”
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Abstract 13700: High Affinity CaM, but Not Normal Affinity CaM Can Prevent Arrhythmias in CPVT Which Mutation is Located at CaM-like Domain of RyR2 by Nishimura, Shigehiko, Yamamoto, Takeshi, Fukui, Go, Maeda, Takako, Hino, Akihiro, Suetomi, Takeshi, Ono, Makoto, Mochizuki, Mamoru, Oda, Tetsuro, Okuda, Shinichi, Kobayashi, Shigeki, Yano, Masafumi

“…IntroductionWe have been previously reported that calmodulin (CaM) binding affinity to RyR2 decreases upon beta stimulation in catecholaminergic polymorphic…”
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Abstract 14991: Dantrolene Cannot Inhibit Aberrant Ca 2+ Release and Arrhythmias Without Calmodulin in Pressure Overload Heart Failure by Fukui, Go, Yamamoto, Takeshi, Kato, Takayoshi, Maeda, Takako, Nishimura, Shigehiko, Hino, Akihiro, Suetomi, Takeshi, Ono, Makoto, Mochizuki, Mamoru, Oda, Tetsuro, Okuda, Shinichi, Kobayashi, Shigeki, Yano, Masafumi

“…Abstract only Background: We have been reported that dantrolene (DAN) binds to N-terminal domain of the cardiac ryanodine receptor (RyR2) and corrects the…”
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Abstract 13816: Dantrolene Enhances Binding of Calmodulin to RyR2 in CPVT Which Mutation Located at Central Domain but Does Not Enhance That in CPVT With Mutation at CaM-like Domain by Nishimura, Shigehiko, Yamamoto, Takeshi, Fukui, Go, Maeda, Takako, Hino, Akihiro, Suetomi, Takeshi, Ono, Makoto, Mochizuki, Mamoru, Oda, Tetsuro, Okuda, Shinichi, Kobayashi, Shigeki, Yano, Masafumi

“…IntroductionCatecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by heterozygous mutation in RyR2 gene. Most mutations are known to be…”
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