Search Results - "MAEDA, Kenji"

HIV Reservoirs and Treatment Strategies toward Curing HIV Infection by Matsuda, Kouki, Maeda, Kenji

“…Combination antiretroviral therapy (cART) has significantly improved the prognosis of individuals living with human immunodeficiency virus (HIV). Acquired…”
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Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2 by Takashita, Emi, Kinoshita, Noriko, Yamayoshi, Seiya, Sakai-Tagawa, Yuko, Fujisaki, Seiichiro, Ito, Mutsumi, Iwatsuki-Horimoto, Kiyoko, Halfmann, Peter, Watanabe, Shinji, Maeda, Kenji, Imai, Masaki, Mitsuya, Hiroaki, Ohmagari, Norio, Takeda, Makoto, Hasegawa, Hideki, Kawaoka, Yoshihiro

“…The in vitro activity of monoclonal antibodies and antiviral agents was assessed against the sublineages of the SARS-CoV-2 variant of concern omicron (BA.1,…”
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Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant by Takashita, Emi, Kinoshita, Noriko, Yamayoshi, Seiya, Sakai-Tagawa, Yuko, Fujisaki, Seiichiro, Ito, Mutsumi, Iwatsuki-Horimoto, Kiyoko, Chiba, Shiho, Halfmann, Peter, Nagai, Hiroyuki, Saito, Makoto, Adachi, Eisuke, Sullivan, David, Pekosz, Andrew, Watanabe, Shinji, Maeda, Kenji, Imai, Masaki, Yotsuyanagi, Hiroshi, Mitsuya, Hiroaki, Ohmagari, Norio, Takeda, Makoto, Hasegawa, Hideki, Kawaoka, Yoshihiro

“…Investigators assessed the in vitro activities of seven monoclonal antibodies and three antiviral drugs against Covid-19 variants of concern. All the…”
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Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication by Maeda, Kenji, Das, Debananda, Kobayakawa, Takuya, Tamamura, Hirokazu, Takeuchi, Hiroaki

“…The history of the human immunodeficiency virus (HIV)/AIDS therapy, which spans over 30 years, is one of the most dramatic stories of science and medicine…”
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Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins by Maeda, Kenji, Anand, Kanchan, Chiapparino, Antonella, Kumar, Arun, Poletto, Mattia, Kaksonen, Marko, Gavin, Anne-Claude

“…The lipid-binding profiles of all lipid-transfer proteins in Saccharomyces cerevisiae are determined and a new subfamily of oxysterol-binding proteins that…”
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Annexin A7 is required for ESCRT III-mediated plasma membrane repair by Sønder, Stine Lauritzen, Boye, Theresa Louise, Tölle, Regine, Dengjel, Jörn, Maeda, Kenji, Jäättelä, Marja, Simonsen, Adam Cohen, Jaiswal, Jyoti K., Nylandsted, Jesper

“…The plasma membrane of eukaryotic cells forms the essential barrier to the extracellular environment, and thus plasma membrane disruptions pose a fatal threat…”
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Third-Dose BNT162b2 Vaccination Elicits Markedly High-Level SARS-CoV-2-Neutralizing Antibodies in Vaccinees Who Responded Poorly to a Second Dose in Japan by Amano, Masayuki, Maeda, Kenji, Tsuchiya, Kiyoto, Shimada, Shinya, Mitsuya, Hiroaki

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A novel highly quantitative and reproducible assay for the detection of anti-SARS-CoV-2 IgG and IgM antibodies by Noda, Kenta, Matsuda, Kouki, Yagishita, Shigehiro, Maeda, Kenji, Akiyama, Yutaro, Terada-Hirashima, Junko, Matsushita, Hiromichi, Iwata, Satoshi, Yamashita, Kazuto, Atarashi, Yusuke, Watanabe, Shunsuke, Ide, Nobuyuki, Yoshida, Tomokazu, Ohmagari, Norio, Mitsuya, Hiroaki, Hamada, Akinobu

“…The quantitative range and reproducibility of current serological tests for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are not optimized…”
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Relation between earthquake swarm activity and tides in the Noto region, Japan by Hirose, Fuyuki, Tamaribuchi, Koji, Kobayashi, Akio, Maeda, Kenji

“…The Noto region in Japan has been experiencing earthquake swarm activity since mid-2018, with repeated rises and falls in activity. Crustal deformation…”
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Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair by Boye, Theresa Louise, Maeda, Kenji, Pezeshkian, Weria, Sønder, Stine Lauritzen, Haeger, Swantje Christin, Gerke, Volker, Simonsen, Adam Cohen, Nylandsted, Jesper

“…Efficient cell membrane repair mechanisms are essential for maintaining membrane integrity and thus for cell life. Here we show that the Ca 2+ - and…”
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Correlates of neutralizing/SARS-CoV-2-S1-binding antibody response with adverse effects and immune kinetics in BNT162b2-vaccinated individuals by Maeda, Kenji, Amano, Masayuki, Uemura, Yukari, Tsuchiya, Kiyoto, Matsushima, Tomoko, Noda, Kenta, Shimizu, Yosuke, Fujiwara, Asuka, Takamatsu, Yuki, Ichikawa, Yasuko, Nishimura, Hidehiro, Kinoshita, Mari, Matsumoto, Shota, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Oka, Shin-ichi, Mikami, Ayako, Sugiura, Wataru, Sato, Toshiyuki, Yoshida, Tomokazu, Shimada, Shinya, Mitsuya, Hiroaki

“…While mRNA vaccines against SARS-CoV-2 are exceedingly effective in preventing symptomatic infection, their immune response features remain to be clarified. In…”
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Efficiency of earthquake forecast models based on earth tidal correlation with background seismicity along the Tonga–Kermadec trench by Hirose, Fuyuki, Maeda, Kenji, Kamigaichi, Osamu

“…The correlation between Earth’s tides and background seismicity has been suggested to become stronger before great earthquakes and weaker after. However,…”
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Evaluating the Use of Sacran, a Polysaccharide Isolated from Aphanothece sacrum , as a Possible Microbicide for Preventing HIV-1 Infection by Matsuda, Kouki, Kariya, Ryusho, Maeda, Kenji, Okada, Seiji

“…Since combination antiretroviral therapy (cART) was introduced to treat human immunodeficiency virus type-1 (HIV-1)/acquired immunodeficiency syndrome (AIDS),…”
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Annexins induce curvature on free-edge membranes displaying distinct morphologies by Boye, Theresa Louise, Jeppesen, Jonas Camillus, Maeda, Kenji, Pezeshkian, Weria, Solovyeva, Vita, Nylandsted, Jesper, Simonsen, Adam Cohen

“…Annexins are a family of proteins characterized by their ability to bind anionic membranes in response to Ca 2+ -activation. They are involved in a multitude…”
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The orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling by Chiapparino, Antonella, Maeda, Kenji, Turei, Denes, Saez-Rodriguez, Julio, Gavin, Anne-Claude

“…Within the eukaryotic cell, more than 1000 species of lipids define a series of membranes essential for cell function. Tightly controlled systems of lipid…”
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The glucagon-like peptide 1 receptor agonist liraglutide attenuates placental ischemia-induced hypertension by Younes, Subhi Talal, Maeda, Kenji J, Sasser, Jennifer, Ryan, Michael J

“…Preeclampsia is a hypertensive disorder of pregnancy characterized by systemic perturbations of nitric oxide function, reflective of generalized endothelial…”
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Neutralization of SARS-CoV-2 with IgG from COVID-19-convalescent plasma by Maeda, Kenji, Higashi-Kuwata, Nobuyo, Kinoshita, Noriko, Kutsuna, Satoshi, Tsuchiya, Kiyoto, Hattori, Shin-ichiro, Matsuda, Kouki, Takamatsu, Yuki, Gatanaga, Hiroyuki, Oka, Shinichi, Sugiyama, Haruhito, Ohmagari, Norio, Mitsuya, Hiroaki

“…While there are various attempts to administer COVID-19-convalescent plasmas to SARS-CoV-2-infected patients, neither appropriate approach nor clinical utility…”
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Dihydroceramide Δ4-Desaturase 1 Is Not Involved in SARS-CoV-2 Infection by Hayashi, Yasuhiro, Matsuda, Kouki, Tanigawa, Kazunari, Tanikawa, Takashi, Maeda, Kenji, Tsuchiya, Kiyoto

“…Dihydroceramide Δ4-desaturase 1 (DEGS1) enzymatic activity is inhibited with N-(4-hydroxyphenyl)-retinamide (4-HPR). We reported previously that 4-HPR…”
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Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations by Yasutake, Yoshiaki, Hattori, Shin-ichiro, Kumamoto, Hiroki, Tamura, Noriko, Maeda, Kenji, Mitsuya, Hiroaki

“…While certain human hepatitis B virus-targeting nucleoside analogs (NAs) serve as crucial anti-HBV drugs, HBV yet remains to be a major global health threat. E…”
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Comparison of Rapid Antigen Tests for COVID-19 by Yamayoshi, Seiya, Sakai-Tagawa, Yuko, Koga, Michiko, Akasaka, Osamu, Nakachi, Ichiro, Koh, Hidefumi, Maeda, Kenji, Adachi, Eisuke, Saito, Makoto, Nagai, Hiroyuki, Ikeuchi, Kazuhiko, Ogura, Takayuki, Baba, Rie, Fujita, Kensuke, Fukui, Takahiro, Ito, Fumimaro, Hattori, Shin-Ichiro, Yamamoto, Kei, Nakamoto, Takato, Furusawa, Yuri, Yasuhara, Atsuhiro, Ujie, Michiko, Yamada, Shinya, Ito, Mutsumi, Mitsuya, Hiroaki, Omagari, Norio, Yotsuyanagi, Hiroshi, Iwatsuki-Horimoto, Kiyoko, Imai, Masaki, Kawaoka, Yoshihiro

“…Reverse transcription-quantitative PCR (RT-qPCR)-based tests are widely used to diagnose coronavirus disease 2019 (COVID-19). As a result that these tests…”
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