Search Results - "MAEDA, Kazuhiro"

The Regulation of Bone Metabolism and Disorders by Wnt Signaling by Maeda, Kazuhiro, Kobayashi, Yasuhiro, Koide, Masanori, Uehara, Shunsuke, Okamoto, Masanori, Ishihara, Akihiro, Kayama, Tomohiro, Saito, Mitsuru, Marumo, Keishi

“…Wnt, a secreted glycoprotein, has an approximate molecular weight of 40 kDa, and it is a cytokine involved in various biological phenomena including ontogeny,…”
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Automatic Generation of SBML Kinetic Models from Natural Language Texts Using GPT by Maeda, Kazuhiro, Kurata, Hiroyuki

“…Kinetic modeling is an essential tool in systems biology research, enabling the quantitative analysis of biological systems and predicting their behavior…”
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Neuromuscular activation of the quadriceps femoris, including the vastus intermedius, during isokinetic knee extensions by Akima, Hiroshi, Maeda, Kazuhiro, Shima, Norihiro

“…The purpose of this study was to compare the neuromuscular activation patterns of the individual muscles of the quadriceps femoris (QF), including the vastus…”
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Inflammation and Bone Metabolism in Rheumatoid Arthritis: Molecular Mechanisms of Joint Destruction and Pharmacological Treatments by Maeda, Kazuhiro, Yoshida, Ken, Nishizawa, Tetsuro, Otani, Kazuhiro, Yamashita, Yu, Okabe, Hinako, Hadano, Yuka, Kayama, Tomohiro, Kurosaka, Daitaro, Saito, Mitsuru

“…Rheumatoid arthritis (RA) is an inflammatory disease characterized by a variety of symptoms and pathologies often presenting with polyarthritis. The primary…”
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PredIL13: Stacking a variety of machine and deep learning methods with ESM-2 language model for identifying IL13-inducing peptides by Kurata, Hiroyuki, Harun-Or-Roshid, Md, Tsukiyama, Sho, Maeda, Kazuhiro

“…Interleukin (IL)-13 has emerged as one of the recently identified cytokine. Since IL-13 causes the severity of COVID-19 and alters crucial biological…”
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Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling by Uehara, Shunsuke, Udagawa, Nobuyuki, Mukai, Hideyuki, Ishihara, Akihiro, Maeda, Kazuhiro, Yamashita, Teruhito, Murakami, Kohei, Nishita, Michiru, Nakamura, Takashi, Kato, Shigeaki, Minami, Yasuhiro, Takahashi, Naoyuki, Kobayashi, Yasuhiro

“…Cytoskeletal reorganization in osteoclasts to form actin rings is necessary for these cells to attach to bone and resorb bone matrices. We delineated the…”
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Behaviors of charged air flow on the step surface with an electric potential by MAEDA, Noboru, MAEDA, Kazuhiro

“…As a new perspective on the influences of the electrically charged air and electric field on the air flow, the natural air flow on a negatively charged…”
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MLAGO: machine learning-aided global optimization for Michaelis constant estimation of kinetic modeling by Maeda, Kazuhiro, Hatae, Aoi, Sakai, Yukie, Boogerd, Fred C, Kurata, Hiroyuki

“…Kinetic modeling is a powerful tool for understanding the dynamic behavior of biochemical systems. For kinetic modeling, determination of a number of kinetic…”
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Gefitinib initiates sterile inflammation by promoting IL-1β and HMGB1 release via two distinct mechanisms by Noguchi, Takuya, Sekiguchi, Yuto, Kudoh, Yuki, Naganuma, Rio, Kagi, Tomohiro, Nishidate, Akiko, Maeda, Kazuhiro, Ishii, Chizuru, Toyama, Takashi, Hirata, Yusuke, Hwang, Gi-Wook, Matsuzawa, Atsushi

“…Anticancer drug gefitinib causes inflammation-based side effects, such as interstitial pneumonitis. However, its mechanisms remain unknown. Here, we provide…”
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Roles of Wnt signals in bone resorption during physiological and pathological states by Maeda, Kazuhiro, Takahashi, Naoyuki, Kobayashi, Yasuhiro

“…Osteoclasts, multinucleated giant cells, are responsible for bone resorption in physiological and pathological conditions such as osteoporosis and rheumatoid…”
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Development of an accurate kinetic model for the central carbon metabolism of Escherichia coli by Jahan, Nusrat, Maeda, Kazuhiro, Matsuoka, Yu, Sugimoto, Yurie, Kurata, Hiroyuki

“…A kinetic model provides insights into the dynamic response of biological systems and predicts how their complex metabolic and gene regulatory networks…”
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Simulation of the crosstalk between glucose and acetaminophen metabolism in a liver zonation model by Maeda, Kazuhiro, Hagimori, Shuta, Sugimoto, Masahiro, Sakai, Yasuyuki, Nishikawa, Masaki

“…The liver metabolizes a variety of substances that sometimes interact and regulate each other. The modeling of a single cell or a single metabolic pathway does…”
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Evidence of genetic contribution to patellar luxation in Toy Poodle puppies by MAEDA, Kazuhiro, INOUE, Mai, TANAKA, Miho, MOMOZAWA, Yukihide

“…Patellar luxation (PL) is one of the most common orthopedic disorders in dogs and a genetic factor is considered to play an important role in the development…”
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Developmental genetic bases behind the independent origin of the tympanic membrane in mammals and diapsids by Kitazawa, Taro, Takechi, Masaki, Hirasawa, Tatsuya, Adachi, Noritaka, Narboux-Nême, Nicolas, Kume, Hideaki, Maeda, Kazuhiro, Hirai, Tamami, Miyagawa-Tomita, Sachiko, Kurihara, Yukiko, Hitomi, Jiro, Levi, Giovanni, Kuratani, Shigeru, Kurihara, Hiroki

“…The amniote middle ear is a classical example of the evolutionary novelty. Although paleontological evidence supports the view that mammals and diapsids…”
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Age-related change in mammographic breast density of women without history of breast cancer over a 10-year retrospective study by Ohmaru, Aiko, Maeda, Kazuhiro, Ono, Hiroyuki, Kamimura, Seiichiro, Iwasaki, Kyoko, Mori, Kazuhiro, Kai, Michiaki

“…Women with higher breast density are at higher risk of developing breast cancer. Breast density is known to affect sensitivity to mammography and to decrease…”
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Comparison of muscle quality and functional capacity between Japanese and Brazilian older individuals by Akima, Hiroshi, Yoshiko, Akito, Radaelli, Régis, Ogawa, Madoka, Shimizu, Kaori, Tomita, Aya, Maeda, Hisashi, Neske, Rodrigo, Teodoro, Juliana, Maeda, Kazuhiro, Tanaka, Noriko, Pinto, Ronei

“…Muscle quality is well-known to decrease with aging and is a risk factor for metabolic abnormalities. However, there is a lack of information on…”
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Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid by Abe, Taiki, Takahashi, Mirei, Kano, Makoto, Amaike, Yuto, Ishii, Chizuru, Maeda, Kazuhiro, Kudoh, Yuki, Morishita, Toru, Hosaka, Takuomi, Sasaki, Takamitsu, Kodama, Susumu, Matsuzawa, Atsushi, Kojima, Hiroyuki, Yoshinari, Kouichi

“…Perfluorocarboxylic acids (PFCAs) including perfluorooctanoic acid (PFOA) are environmental pollutants showing high accumulation, thermochemical stability and…”
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Variations in the Extensor Pollicis Brevis-Extensor Pollicis Longus Tendon Complex by Nishimura, Reiji, Hashimoto, Tohru, Yano, Tohru, Bo, Hideaki, Maeda, Kazuhiro, Okabe, Masataka, Miyawaki, Takeshi

“…Despite several reports on the running of the extensor pollicis brevis (EPB) tendons, the classification of tendon insertions remains ununified due to…”
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RCGAToolbox: A Real-coded Genetic Algorithm Software for Parameter Estimation of Kinetic Models by Maeda, Kazuhiro, Boogerd, Fred C., Kurata, Hiroyuki

“…Kinetic modeling is essential for understanding the dynamic behavior of biochemical networks, such as metabolic and signal transduction pathways. However,…”
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Coupling analysis of unsteady aerodynamics and vehicle behavior with road input: Modeling and verification in road tests by MAEDA, Kazuhiro, TSUBAKINO, Daisuke, HARA, Susumu, SASOH, Akihiro

“…This paper discusses that the unsteady aerodynamic forces caused by vehicle motion in road input have a large influence on the vehicle behaviors. In the…”
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