Search Results - "MADSEN, S"
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1
MicroRNAs in metabolism
Published in Acta Physiologica (01-02-2017)“…MicroRNAs (miRNAs) have within the past decade emerged as key regulators of metabolic homoeostasis. Major tissues in intermediary metabolism important during…”
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2
Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells
Published in Nature genetics (01-11-2020)“…Adipocyte differentiation is driven by waves of transcriptional regulators that reprogram the enhancer landscape and change the wiring of the promoter…”
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3
Aquaporin expression dynamics in osmoregulatory tissues of Atlantic salmon during smoltification and seawater acclimation
Published in Journal of experimental biology (01-02-2010)“…Osmotic balance in fish is maintained through the coordinated regulation of water and ion transport performed by epithelia in intestine, kidney and gill. In…”
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4
Unexpected diversity among small-scale sample replicates of defined plant root compartments
Published in The ISME Journal (01-04-2022)“…Community assembly processes determine patterns of species distribution and abundance which are central to the ecology of microbiomes. When studying plant root…”
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Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5
Published in Cell metabolism (01-04-2014)“…We report the identification and characterization of a five-carbon protein posttranslational modification (PTM) called lysine glutarylation (Kglu). This…”
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6
Classical Density Functional Theory: Representability and Universal Bounds
Published in Journal of statistical physics (13-03-2023)“…We provide upper and lower bounds on the lowest free energy of a classical system at given one-particle density ρ ( x ) . We study both the canonical and…”
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7
Pain and pain mechanisms in patients with inflammatory arthritis: A Danish nationwide cross-sectional DANBIO registry survey
Published in PloS one (07-07-2017)“…Central pain mechanisms may be prominent in subsets of patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and other spondyloarthritis (SpA)…”
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8
Profiling of Substrates for Zinc-dependent Lysine Deacylase Enzymes: HDAC3 Exhibits Decrotonylase Activity In Vitro
Published in Angewandte Chemie International Edition (03-09-2012)“…Systematic screening of the activities of the eleven human zinc‐dependent lysine deacylases against a series of fluorogenic substrates (see scheme) as well as…”
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9
CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids
Published in Nucleic acids research (06-05-2022)“…Many prokaryotes encode CRISPR-Cas systems as immune protection against mobile genetic elements (MGEs), yet a number of MGEs also harbor CRISPR-Cas components…”
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10
The SuperCam Instrument Suite on the Mars 2020 Rover: Science Objectives and Mast-Unit Description
Published in Space science reviews (01-04-2021)“…On the NASA 2020 rover mission to Jezero crater, the remote determination of the texture, mineralogy and chemistry of rocks is essential to quickly and…”
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11
Tofacitinib Inhibits Collagen Biomarkers Of Fibrosis In Tgf- ΒStimulated Fibroblast-Like Synoviocytes From Patients With Osteoarthritis
Published in Osteoarthritis and cartilage (01-03-2023)Get full text
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12
Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine
Published in Proceedings of the National Academy of Sciences - PNAS (03-01-2012)“…The mucin MUC1 is typically aberrantly glycosylated by epithelial cancer cells manifested by truncated O-linked saccharides. The resultant glycopeptide…”
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13
A quantum heat machine from fast optomechanics
Published in New journal of physics (01-10-2020)“…We consider a thermodynamic machine in which the working fluid is a quantized harmonic oscillator that is controlled on timescales that are much faster than…”
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14
Lipolysis regulates major transcriptional programs in brown adipocytes
Published in Nature communications (08-07-2022)“…β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating both lipolysis and transcription of thermogenic genes, thereby expanding the…”
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15
Water Transport and Functional Dynamics of Aquaporins in Osmoregulatory Organs of Fishes
Published in The Biological bulletin (Lancaster) (01-08-2015)“…Aquaporins play distinct roles for water transport in fishes as they do in mammals—both at the cellular, organ, and organismal levels. However, with over…”
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16
Individual variations in 'brain age' relate to early-life factors more than to longitudinal brain change
Published in eLife (10-11-2021)“…is a widely used index for quantifying individuals' brain health as deviation from a normative brain aging trajectory. Higher-than-expected is thought…”
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17
Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight
Published in Angewandte Chemie International Edition (20-11-2017)“…The sirtuin enzymes are important regulatory deacylases in a variety of biochemical contexts and may therefore be potential therapeutic targets through either…”
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18
A population-based prospective study of optic neuritis
Published in Multiple sclerosis (01-12-2017)“…Background: Optic neuritis (ON) is often associated with multiple sclerosis (MS). Early diagnosis is critical to optimal patient management. Objective: To…”
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Correlations between fatigue and disease duration, disease activity, and pain in patients with rheumatoid arthritis: a systematic review
Published in Scandinavian journal of rheumatology (03-07-2016)“…Objectives: Rheumatoid arthritis (RA) patients suffer from disabling fatigue but the causes of this condition are unknown. Our aim was to assess which of the…”
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20
Modelling of the dynamic polarizability of macromolecules for single-molecule optical biosensing
Published in Scientific reports (07-02-2022)“…The structural dynamics of macromolecules is important for most microbiological processes, from protein folding to the origins of neurodegenerative disorders…”
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