Search Results - "MADSBAD, STEN"

Review of head-to-head comparisons of glucagon-like peptide-1 receptor agonists by Madsbad, Sten

“…Currently, six glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are approved for treating type 2 diabetes. These fall into two classes based on their…”
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Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery by Madsbad, Sten, Prof, Dirksen, Carsten, PhD, Holst, Jens J, Prof

“…Summary Bariatric surgery is the most effective treatment for obesity and also greatly improves glycaemic control, often within days after surgery,…”
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Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined by Lundgren, Julie R, Janus, Charlotte, Jensen, Simon B.K, Juhl, Christian R, Olsen, Lisa M, Christensen, Rasmus M, Svane, Maria S, Bandholm, Thomas, Bojsen-Møller, Kirstine N, Blond, Martin B, Jensen, Jens-Erik B, Stallknecht, Bente M, Holst, Jens J, Madsbad, Sten, Torekov, Signe S

“…In this trial, adults with obesity without diabetes were randomly assigned, after an 8-week low-calorie diet, to 1 year of placebo, an exercise program,…”
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Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations-Role of Carbohydrate and Energy Availability by Bojsen-Møller, Kirstine N, Lundsgaard, Anne-Marie, Madsbad, Sten, Kiens, Bente, Holst, Jens Juul

“…Hyperinsulinemia is the hallmark of insulin resistance in obesity, and the relative importance of insulin clearance, insulin resistance, and insulin…”
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Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss by Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, Kirstine N., Svane, Maria Saur, Jørgensen, Nils Bruun, Dirksen, Carsten, Martinussen, Christoffer

“…Gastric bypass surgery leads to profound changes in the secretion of gut hormones with effects on metabolism, appetite, and food intake. Here, we discuss their…”
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Proteomics reveals the effects of sustained weight loss on the human plasma proteome by Geyer, Philipp E, Wewer Albrechtsen, Nicolai J, Tyanova, Stefka, Grassl, Niklas, Iepsen, Eva W, Lundgren, Julie, Madsbad, Sten, Holst, Jens J, Torekov, Signe S, Mann, Matthias

“…Sustained weight loss is a preferred intervention in a wide range of metabolic conditions, but the effects on an individual's health state remain ill‐defined…”
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Non-insulin drugs to treat hyperglycaemia in type 1 diabetes mellitus by Frandsen, Christian Seerup, Dr, Dejgaard, Thomas Fremming, MD, Madsbad, Sten, Prof

“…Summary Insulin treatment of individuals with type 1 diabetes has shortcomings and many patients do not achieve glycaemic and metabolic targets. Consequently,…”
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GLP-1 as a mediator in the remission of type 2 diabetes after gastric bypass and sleeve gastrectomy surgery by Madsbad, Sten, Holst, Jens J

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Postprandial Nutrient Handling and Gastrointestinal Hormone Secretion After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy by Svane, Maria S., Bojsen-Møller, Kirstine N., Martinussen, Christoffer, Dirksen, Carsten, Madsen, Jan L., Reitelseder, Søren, Holm, Lars, Rehfeld, Jens F., Kristiansen, Viggo B., van Hall, Gerrit, Holst, Jens J., Madsbad, Sten

“…Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) induce substantial weight loss and improve glycemic control in patients with type 2 diabetes, but…”
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Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor by Holst, Jens Juul, M.D, Madsbad, Sten, M.D

“…Abstract GLP-1 secretion in response to meals is dramatically increased after gastric bypass operations. GLP-1 is a powerful insulinotropic and anorectic…”
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Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes by Holst, Jens J, Knop, Filip K, Vilsbøll, Tina, Krarup, Thure, Madsbad, Sten

“…[...] the studies also demonstrate that common variants have a low impact on these parameters, and a clear genetic explanation for the loss of incretin effect…”
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Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: a randomised controlled trial by Thomsen, Mads N., Skytte, Mads J., Samkani, Amirsalar, Carl, Martin H., Weber, Philip, Astrup, Arne, Chabanova, Elizaveta, Fenger, Mogens, Frystyk, Jan, Hartmann, Bolette, Holst, Jens J., Larsen, Thomas M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen B., Krarup, Thure

“…Aims/hypothesis Lifestyle modification and weight loss are cornerstones of type 2 diabetes management. However, carbohydrate restriction may have…”
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Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration by Pedersen, Julie S., Rygg, Marte O., Chrøis, Karoline, Sustarsic, Elahu G., Gerhart-Hines, Zach, Wever Albrechtsen, Nicolai J., Serizawa, Reza R., Kristiansen, Viggo B., Basse, Astrid L., Boilesen, Astrid E. B., Olsen, Beth H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, Steen, Bendtsen, Flemming, Dela, Flemming

“…Impaired mitochondrial oxidative phosphorylation (OXPHOS) in liver tissue has been hypothesised to contribute to the development of nonalcoholic…”
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The impact of surgery and oncological treatment on risk of type 2 diabetes onset in patients with colorectal cancer: nationwide cohort study in Denmark by Krag, Caroline, Svane, Maria Saur, Madsbad, Sten, Graversen, Susanne Boel, Christensen, Jesper Frank, Sørensen, Thorkild I A, Lehrskov, Louise Lang, Laurberg, Tinne

“…Comorbidity with type 2 diabetes (T2D) results in worsening of cancer-specific and overall prognosis in colorectal cancer (CRC) patients. The treatment of CRC…”
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What is Diabetes Remission? by Holst, Jens J., Madsbad, Sten

“…Remission of type 2 diabetes is generally thought of as being able to maintain hemoglobin A1c (HbAc1) levels below a certain threshold without any antidiabetic…”
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Effects of Liraglutide on Heart Rate and Heart Rate Variability: A Randomized, Double-Blind, Placebo-Controlled Crossover Study by Kumarathurai, Preman, Anholm, Christian, Larsen, Bjørn S, Olsen, Rasmus Huan, Madsbad, Sten, Kristiansen, Ole, Nielsen, Olav W, Haugaard, Steen B, Sajadieh, Ahmad

“…Reduced heart rate variability (HRV) and increased heart rate (HR) have been associated with cardiovascular mortality. Glucagon-like peptide 1 receptor…”
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Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial by Leiter, Lawrence A, Bain, Stephen C, Hramiak, Irene, Jódar, Esteban, Madsbad, Sten, Gondolf, Theis, Hansen, Thomas, Holst, Ingrid, Lingvay, Ildiko

“…The SUSTAIN 6 trial demonstrated that once-weekly semaglutide (0.5 and 1.0 mg) significantly reduced major adverse cardiovascular (CV) events (MACE) vs placebo…”
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota by Palleja, Albert, Kashani, Alireza, Allin, Kristine H, Nielsen, Trine, Zhang, Chenchen, Li, Yin, Brach, Thorsten, Liang, Suisha, Feng, Qiang, Jørgensen, Nils Bruun, Bojsen-Møller, Kirstine N, Dirksen, Carsten, Burgdorf, Kristoffer S, Holst, Jens J, Madsbad, Sten, Wang, Jun, Pedersen, Oluf, Hansen, Torben, Arumugam, Manimozhiyan

“…Roux-en-Y gastric bypass (RYGB) is an effective means to achieve sustained weight loss for morbidly obese individuals. Besides rapid weight reduction, patients…”
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Impact of prolonged fasting on insulin secretion, insulin action, and hepatic versus whole body insulin secretion disposition indices in healthy young males by Jørgensen, Sine W, Hjort, Line, Gillberg, Linn, Justesen, Louise, Madsbad, Sten, Brøns, Charlotte, Vaag, Allan A

“…The extent to which reduced insulin secretion during prolonged fasting reflects failure to compensate for whole body insulin resistance or a normal adjustment…”
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The Effect of Bariatric Surgery on Healthcare Costs and Labor Market Attachment by Bøgelund, Mette, Jørgensen, Nils B., Madsbad, Sten, Spanggaard, Maria, Panton, Ulrik H., Pedersen, Mikkel H., Johansen, Pierre

“…Purpose We aimed to estimate the total cost of bariatric surgery in Denmark. Materials and Methods The study population included all Danish citizens ≥ 18 years…”
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