Search Results - "MADISON, B"

Srebp2: A master regulator of sterol and fatty acid synthesis by Madison, Blair B

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Assessing the relationship between gun ownership and fear of mass shootings by Gerdes, Madison B

“…Gun sales spike after mass shooting incidents. As firearm presence is associated with numerous health and safety risks, it is imperative to understand what…”
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Synthesis of Isomerically Pure (Z)‑Alkenes from Terminal Alkynes and Terminal Alkenes: Silver-Catalyzed Hydroalkylation of Alkynes by Lee, Mitchell T, Goodstein, Madison B, Lalic, Gojko

“…Alkenes are an important class of compounds common among biologically active molecules and often are used as intermediates in organic synthesis. Many alkenes…”
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Mechanisms and regulation of replication fork reversal by Adolph, Madison B., Cortez, David

“…DNA replication is remarkably accurate with estimates of only a handful of mutations per human genome per cell division cycle. Replication stress caused by DNA…”
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Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability by Mohamed, Taha, Adolph, Madison B., Cortez, David

“…Genome integrity requires complete and accurate DNA replication once per cell division cycle. Replication stress poses obstacles to this process that must be…”
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Srebp2: A master regulator of sterol and fatty acid synthesis1 by Madison, Blair B.

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Diastereodivergent Reductive Cross Coupling of Alkynes through Tandem Catalysis: Z- and E‑Selective Hydroarylation of Terminal Alkynes by Armstrong, Megan K, Goodstein, Madison B, Lalic, Gojko

“…A diastereodivergent hydroarylation of terminal alkynes is accomplished using tandem catalysis. The hydroarylation allows highly selective synthesis of both E…”
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MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications by Strubberg, Ashlee M, Madison, Blair B

“…MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and trigger mRNA degradation. Of the ∼1900 miRNA-encoding genes present in the…”
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S3353 A Rare Case of Esophageal Squamous Cell Carcinoma Arising From Barrett’s Segment With High Grade Dysplasia by Peregoy, Madison B., Forbes, Chelsea, Young, Patrick E.

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Lineup size influences voice identification accuracy by Harvey, Madison B., Giroux, Megan, Price, Heather L.

“…We investigated the effects of lineup size, target presence, and target sex on voice identification accuracy. In Study 1, participants identified a female…”
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Genetically influenced tobacco and alcohol use behaviors impact erythroid trait variation by Shivakumar, Shriya, Wilken, Madison B, Tsao, Victor, Bitarello, Bárbara D, Thom, Christopher S

“…Genome wide association studies (GWAS) have associated thousands of loci with quantitative human blood trait variation. Loci and related genes that impact…”
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Mechanisms underlying age-associated manifestation of cardiac sodium channel gain-of-function by Nowak, Madison B., Poelzing, Steven, Weinberg, Seth H.

“…Cardiac action potentials are initiated by sodium ion (Na+) influx through voltage-gated Na+ channels. Na+ channel gain-of-function (GOF) can arise in…”
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Distal Mutations in the β‑Clamp of DNA Polymerase III Disrupt DNA Orientation and Affect Exonuclease Activity by Berger, Madison B., Cisneros, G. Andrés

“…DNA polymerases are responsible for the replication and repair of DNA found in all DNA-based organisms. DNA Polymerase III is the main replicative polymerase…”
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APOBEC3 Host Restriction Factors of HIV-1 Can Change the Template Switching Frequency of Reverse Transcriptase by Adolph, Madison B., Ara, Anjuman, Chelico, Linda

“…The APOBEC3 family of deoxycytidine deaminases has the ability to restrict HIV-1 through deamination-dependent and deamination-independent mechanisms. Although…”
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Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure by McDaniel, Yumeng Z, Wang, Dake, Love, Robin P, Adolph, Madison B, Mohammadzadeh, Nazanin, Chelico, Linda, Mansky, Louis M

“…Abstract The human apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (APOBEC3, A3) family member proteins can deaminate cytosines in…”
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The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis by Starrett, Gabriel J., Luengas, Elizabeth M., McCann, Jennifer L., Ebrahimi, Diako, Temiz, Nuri A., Love, Robin P., Feng, Yuqing, Adolph, Madison B., Chelico, Linda, Law, Emily K., Carpenter, Michael A., Harris, Reuben S

“…Cytosine mutations within TCA/T motifs are common in cancer. A likely cause is the DNA cytosine deaminase APOBEC3B (A3B). However, A3B -null breast tumours…”
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LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms by King, C E, Wang, L, Winograd, R, Madison, B B, Mongroo, P S, Johnstone, C N, Rustgi, A K

“…Lin28b is an RNA-binding protein that inhibits biogenesis of let-7 microRNAs. LIN28B is overexpressed in diverse cancers, yet a specific role in the molecular…”
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A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses by Wittkopp, Cristina J, Adolph, Madison B, Wu, Lily I, Chelico, Linda, Emerman, Michael

“…Humans express seven human APOBEC3 proteins, which can inhibit viruses and endogenous retroelements through cytidine deaminase activity. The seven paralogs…”
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Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B by Adolph, Madison B, Love, Robin P, Feng, Yuqing, Chelico, Linda

“…The single-stranded DNA cytidine deaminases APOBEC3B, APOBEC3H haplotype I, and APOBEC3A can contribute to cancer through deamination of cytosine to form…”
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Cellular Size, Gap Junctions, and Sodium Channel Properties Govern Developmental Changes in Cardiac Conduction by Nowak, Madison B, Veeraraghavan, Rengasayee, Poelzing, Steven, Weinberg, Seth H

“…Electrical conduction in cardiac ventricular tissue is regulated via sodium (Na ) channels and gap junctions (GJs). We and others have recently shown that Na…”
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