Search Results - "MADHUMATHI, Jayaprakasam"
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Establishing Antimicrobial Resistance Surveillance & Research Network in India: Journey so far
Published in Indian journal of medical research (New Delhi, India : 1994) (01-02-2019)“…The Indian Council of Medical Research, in 2013, initiated the Antimicrobial Resistance Surveillance & Research Network (AMRSN) to enable compilation of data…”
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Evaluation of molecular diagnostic test for detection of adult pulmonary tuberculosis: A generic protocol
Published in Indian journal of medical research (New Delhi, India : 1994) (01-02-2024)“…Tuberculosis (TB) continues to be the second most-leading cause of death due to a single infectious agent as of 2022 after COVID-19. Many affordable new…”
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Policy document on antimicrobial stewardship practices in India
Published in Indian journal of medical research (New Delhi, India : 1994) (01-02-2019)“…Antimicrobial resistance (AMR) in India has become a great threat because of high rate of infectious diseases. One of the key contributing factors is high…”
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Use of “Social Media”—an Option for Spreading Awareness in Infection Prevention
Published in Current treatment options in infectious disease (2021)“…Purpose of review There is a need for enhanced adoption of infection prevention and control (IPC) practices in both healthcare settings and the entire…”
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Community voices around COVID-19 vaccine in Chennai, India: A qualitative exploration during early phase of vaccine rollout
Published in Indian journal of medical research (New Delhi, India : 1994) (01-05-2022)“…Background & objectives: Globally, vaccination is considered as an important public health strategy to mitigate the impact of the COVID-19 pandemic. The…”
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Association between ambient air pollutants and meteorological factors with SARS-CoV-2 transmission and mortality in India: an exploratory study
Published in Environmental health (19-11-2021)“…The Coronavirus disease 2019 (COVID-19) pandemic poses a serious public health concern worldwide. Certain regions of the globe were severely affected in terms…”
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Menstrual Hygiene Practices of Adolescent Girls in Rural Maharashtra
Published in Indian journal of gender studies (01-02-2021)“…Menstrual practices of adolescent girls in rural parts of India are greatly influenced by taboos and socio-cultural beliefs. In this study, the menstrual…”
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CD25 targeted therapy of chemotherapy resistant leukemic stem cells using DR5 specific TRAIL peptide
Published in Stem cell research (01-03-2017)“…Chemotherapy resistant leukemic stem cells (LSCs) are being targeted as a modern therapeutic approach to prevent disease relapse. LSCs isolated from…”
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Human anthrax in India in recent times: A systematic review & risk mapping
Published in One health (01-06-2023)“…The disease anthrax occurs generally in herbivores and the causative organism (Bacillus anthracis) infects humans who come in contact with infected animals or…”
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Novel TNF-related Apoptotic-inducing Ligand-based Immunotoxin for Therapeutic Targeting of CD25 Positive Leukemia
Published in Targeted oncology (01-08-2016)“…Background Human TNF-related apoptotic-inducing ligand (TRAIL) has been used successfully for targeted therapy of almost all cancers. Leukemia is the most…”
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Immunotoxin therapy for hematologic malignancies: where are we heading?
Published in Drug discovery today (01-02-2016)“…•The review describes recent advances in immunotoxin therapy in leukemias.•The review focuses overview of immunotoxins classified by target surface…”
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Anticancer effect of acid ceramidase inhibitor ceranib-2 in human breast cancer cell lines MCF-7, MDA MB-231 by the activation of SAPK/JNK, p38 MAPK apoptotic pathways, inhibition of the Akt pathway, downregulation of ERα
Published in Anti-cancer drugs (01-01-2018)“…Acid ceramidase is the key enzyme of the ceramide metabolic pathway, which plays a vital role in regulating ceramide – sphingosine-1-phosphate rheostat…”
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Wucherria bancrofti glutathione S-Transferase: Insights into the 2.3 Å resolution X-ray structure and function, a therapeutic target for human lymphatic filariasis
Published in Biochemical and biophysical research communications (10-11-2018)“…The notoriety of parasitic nematode survival is directly related to chronic pathogenicity, which is evident in human lymphatic filariasis. It is a disease of…”
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Immunotoxin therapy for hematologic malignancies: where are we heading?: Post screen
Published in Drug discovery today (01-02-2016)“…The identification of numerous unique targets in recent years has led to the development of various immunotoxins (ITs) for treating hematological malignancies…”
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Biodegradable poly-l-lactide based microparticles as controlled release delivery system for filarial vaccine candidate antigens
Published in European journal of pharmacology (15-01-2015)“…Modern recombinant vaccines are less immunogenic than conventional vaccines which require adjuvants to enhance the effect of a vaccine. Alum is being used as a…”
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RNA-extraction-free diagnostic method to detect SARS-CoV-2: an assessment from two states, India
Published in Epidemiology and infection (02-11-2021)“…With increasing demand for large numbers of testing during the coronavirus disease 2019 pandemic, alternative protocols were developed with shortened…”
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Protective immune responses of recombinant VP2 subunit antigen of infectious bursal disease virus in chickens
Published in Veterinary immunology and immunopathology (15-08-2012)“…Infectious bursal disease virus (IBDV) is the causative agent of Gumboro disease and poses a huge threat to poultry industry. The risks associated with…”
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DNA vaccination with VP2 gene fragment confers protection against Infectious Bursal Disease Virus in Chickens
Published in Veterinary microbiology (25-06-2014)“…Infectious Bursal Disease Virus (IBDV) causes immunosuppression in young chickens by destruction of antibody producing B cells in the Bursa of Fabricius and…”
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Antigen detection assay with parasite specific monoclonal antibodies for diagnosis of lymphatic filariasis
Published in Clinica chimica acta (18-09-2011)“…Lymphatic filariasis is a painful and profoundly disfiguring disease. Infection is usually acquired in childhood but its visible manifestations occur later in…”
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Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis
Published in Vaccine (12-07-2010)“…Abstract Although multi-epitope vaccines have been evaluated for various diseases, they have not yet been investigated for lymphatic filariasis. Here, we…”
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