Search Results - "MACLAURIN, J"

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics by Irrcher, I., Aleyasin, H., Seifert, E.L., Hewitt, S.J., Chhabra, S., Phillips, M., Lutz, A.K., Rousseaux, M.W.C., Bevilacqua, L., Jahani-Asl, A., Callaghan, S., MacLaurin, J.G., Winklhofer, K.F., Rizzu, P., Rippstein, P., Kim, R.H., Chen, C.X., Fon, E.A., Slack, R.S., Harper, M.E., McBride, H.M., Mak, T.W., Park, D.S.

“…Growing evidence highlights a role for mitochondrial dysfunction and oxidative stress as underlying contributors to Parkinson's disease (PD) pathogenesis. DJ-1…”
Get full text

Stochastic oscillators in biology: introduction to the special issue by MacLaurin, J., Fellous, J. M., Thomas, P. J., Lindner, B.

Get full text

Determination of effective brain connectivity from activity correlations by MacLaurin, J N, Robinson, P A

“…Effective connectivity embodied in transfer functions is derived from symmetric-network activity correlations under task-free conditions via a recent causal…”
Get more information

Variation by Geographic Scale in the Migration-Environment Association: Evidence from Rural South Africa by Hunter, Lori M., Leyk, Stefan, Maclaurin, Galen J., Nawrotzki, Raphael, Twine, Wayne, Erasmus, Barend F.N., Collinson, Mark

“…Scholarly understanding of human migration’s environmental dimensions has greatly advanced in the past several years, motivated in large part by public and…”
Get full text

Apoptosis-Inducing Factor Is Involved in the Regulation of Caspase-Independent Neuronal Cell Death by Cregan, Sean P., Fortin, Andre, MacLaurin, Jason G., Callaghan, Steven M., Cecconi, Francesco, Yu, Seong-Woon, Dawson, Ted M., Dawson, Valina L., Park, David S., Kroemer, Guido, Slack, Ruth S.

“…Caspase-independent death mechanisms have been shown to execute apoptosis in many types of neuronal injury. P53 has been identified as a key regulator of…”
Get full text

Extending the geographic extent of existing land cover data using active machine learning and covariate shift corrective sampling by Maclaurin, Galen J., Leyk, Stefan

“…Consistent land cover data provided at national and regional scales are increasingly relevant for a wide range of research topics from landscape ecology to…”
Get full text

Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons by Cregan, Sean P, MacLaurin, Jason G, Craig, Constance G, Robertson, George S, Nicholson, Donald W, Park, David S, Slack, Ruth S

“…p53 is a pivotal molecule regulating the death of neurons both after acute injury and during development. The molecular mechanisms by which p53 induces…”
Get full text

APAF1 Is a Key Transcriptional Target for p53 in the Regulation of Neuronal Cell Death by Fortin, Andre, Cregan, Sean P., MacLaurin, Jason G., Kushwaha, Neena, Hickman, Emma S., Thompson, Charlie S., Hakim, Antoine, Albert, Paul R., Cecconi, Francesco, Helin, Kristian, Park, David S., Slack, Ruth S.

“…p53 is a transcriptional activator which has been implicated as a key regulator of neuronal cell death after acute injury. We have shown previously that…”
Get full text

Rural Outmigration, Natural Capital, and Livelihoods in South Africa by Hunter, Lori M., Nawrotzki, Raphael, Leyk, Stefan, Maclaurin, Galen J., Twine, Wayne, Collinson, Mark, Erasmus, Barend

“…ABSTRACT Rural households across the globe engage in both migration and natural resource use as components of livelihood strategies designed to meet household…”
Get full text

Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development by Ferguson, Kerry L., Vanderluit, Jacqueline L., Hébert, Jean M., McIntosh, W.C., Tibbo, Emma, MacLaurin, Jason G., Park, David S., Wallace, Valerie A., Vooijs, Marc, McConnell, Susan K., Slack, Ruth S.

“…Correct cell cycle regulation and terminal mitosis are critical for nervous system development. The retinoblastoma (Rb) protein is a key regulator of these…”
Get full text

The Proapoptotic Gene SIVA Is a Direct Transcriptional Target for the Tumor Suppressors p53 and E2F1 by Fortin, Andre, MacLaurin, Jason G, Arbour, Nicole, Cregan, Sean P, Kushwaha, Neena, Callaghan, Steven M, Park, David S, Albert, Paul R, Slack, Ruth S

“…The p53 tumor suppressor gene is believed to play an important role in neuronal cell death in acute neurological disease and in neurodegeneration. The p53…”
Get full text

Spatially and temporally varying associations between temporary outmigration and natural resource availability in resource-dependent rural communities in South Africa: A modeling framework by Leyk, Stefan, Maclaurin, Galen J., Hunter, Lori M., Nawrotzki, Raphael, Twine, Wayne, Collinson, Mark, Erasmus, Barend

“…Migration-environment models tend to be aspatial within chosen study regions, although associations between temporary outmigration and environmental…”
Get full text

Canadian Incidence Study of Reported Child Abuse and Neglect: Methodology by Trocmé, Nico M., MacLaurin, Bruce J., Fallon, Barbara A., Daciuk, Joanne F., Tourigny, Marc, Billingsley, Diane A.

“…This article describes the methodology of the first Canada-wide study of the incidence and characteristics of reported child abuse and neglect. Child welfare…”
Get full text

Helper-dependent adenovirus vectors : Their use as a gene delivery system to neurons by CREGAN, S. P, MACLAURIN, J, GENDRON, T. F, CALLAGHAN, S. M, PARK, D. S, PARKS, R. J, GRAHAM, F. L, MORLEY, P, SLACK, R. S

“…Recombinant adenovirus vectors have provided a major advance in gene delivery systems for post-mitotic neurons. However, the use of these first generation…”
Get full text

Variation by Geographic Scale in the Migration-Environment Association: Evidence from Rural South Africa by Hunter, Lori M, Leyk, Stefan, Maclaurin, Galen J, Nawrotzki, Raphael, Twine, Wayne, Erasmus, Barend FN, Collinson, Mark

“…Scholarly understanding of human migration’s environmental dimensions has greatly advanced in the past several years, motivated in large part by public and…”
Get full text

An analysis of the gaming industry in the Niagara region by MacLaurin, Donald J, Wolstenholme, Steve

“…Purpose - The aim of this paper is to profile the casino gaming industry in Niagara Falls Canada, home to Canada's largest and busiest casino infrastructure…”
Get full text

Level of Street Involvement and Health and Health Services Use of Calgary Street Youth by Worthington, Catherine A., MacLaurin, Bruce J.

“…Objectives: To examine differences in health risks, health outcomes and health services use of Calgary street-involved youth by level of street involvement to…”
Get full text

Caspase 3 Deficiency Rescues Peripheral Nervous System Defect in Retinoblastoma Nullizygous Mice by Simpson, Matthew T. W, MacLaurin, Jason G, Xu, Daigen, Ferguson, Kerry L, Vanderluit, Jacqueline L, Davoli, Maria A, Roy, Sophie, Nicholson, Donald W, Robertson, George S, Park, David S, Slack, Ruth S

“…The retinoblastoma tumor suppressor protein, pRb, is a key regulator of cell cycle and has been implicated in the terminal differentiation of neuronal cells…”
Get full text

Impact of Food-Borne Illness on Food Safety Concerns of International Air Travellers by MacLaurin, Tanya L., MacLaurin, Donald J., Loi, Loi Soh

“…This study examines international air travellers' attitudes and perceptions of the importance of food safety, sources of information on food safety, and the…”
Get full text

Temporal replication of the national land cover database using active machine learning by Maclaurin, Galen J., Leyk, Stefan

“…Regional and national level land cover datasets, such as the National Land Cover Database (NLCD) in the United States, have become an important resource in…”
Get full text