Search Results - "MACLATCHY, D. L"
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Effects of water-borne 4-nonylphenol and 17β-estradiol exposures during parr-smolt transformation on growth and plasma IGF-I of Atlantic salmon ( Salmo salar L.)
Published in Aquatic toxicology (25-02-2004)“…4-Nonylphenol (4-NP) is an endocrine disrupting substance (EDS) capable of mimicking the action of 17β-estradiol (E 2). It has been hypothesized that 4-NP in a…”
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Effects of metal mining effluent on Atlantic salmon ( Salmo salar) and slimy sculpin ( Cottus cognatus): using artificial streams to assess existing effects and predict future consequences
Published in The Science of the total environment (01-05-2005)“…In the summer of 2000, the effects of metal mine discharge on fish growth and exercise performance were assessed at a Zn–Pb–Cu mine in New Brunswick, Canada…”
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3
Assessment of the potential of the rock gunnel (Pholis gunnellus) along the Atlantic coast of Canada as a species for monitoring the reproductive impacts of contaminant exposures
Published in Environmental monitoring and assessment (01-05-2007)“…Evaluating the impacts of point source discharges on fish species in estuarine environments can be challenging because of a paucity of resident species. We…”
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4
The Phytoestrogen β-Sitosterol Alters the Reproductive Endocrine Status of Goldfish
Published in Toxicology and applied pharmacology (01-10-1995)“…There is growing awareness that chemicals in the environment may function as hormone mimics and affect endocrine function in wildlife. In this study, the…”
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5
Identification and treatment of a waste stream at a bleached-kraft pulp mill that depresses a sex steroid in the mummichog (Fundulus heteroclitus)
Published in Environmental toxicology and chemistry (01-05-2001)“…Changes to indicators of reproductive performance have been documented in fish exposed to some bleached kraft pulp mill effluents (BKPMEs). However, responses…”
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6
The effects of 17-α-ethinylestradiol (EE2) on molecular signaling cascades in mummichog (Fundulus heteroclitus)
Published in Aquatic toxicology (15-06-2013)“…•Mummichog (Fundulus heteroclitus) were exposed to 17-α-ethinylestradiol (EE2).•Ovarian stage and plasma estrogen were not affected by EE2 but T was…”
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Morphological abnormalities during early-life development of the estuarine mummichog, Fundulus heteroclitus, as an indicator of androgenic and anti-androgenic endocrine disruption
Published in Aquatic toxicology (04-03-2005)“…We tested the hypothesis that gross morphological abnormalities are a sensitive indicator of exposure to waterborne androgenic and anti-androgenic compounds…”
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An interlaboratory study on the use of steroid hormones in examining endocrine disruption
Published in Environmental toxicology and chemistry (01-09-2001)“…In recent years, there has been an increased use of the measurement of sex steroid hormone levels in the blood of animals exposed to chemicals as an indicator…”
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9
Properties of T4 5'-deiodinating systems in various tissues of the rainbow trout, Oncorhynchus mykiss
Published in General and comparative endocrinology (01-05-1992)“…L-Thyroxine (T4) 5'-monodeiodinase (5'D) activity was examined in the microsomal fractions of liver, kidney, gill, white skeletal muscle, and red blood cells…”
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Effects of cortisol on aspects of 3,5,3'-triiodo-L-thyronine metabolism in rainbow trout (Oncorhynchus mykiss)
Published in General and comparative endocrinology (01-02-1991)“…Aspects of 3,5,3'-triiodo-L-thyronine (T3) metabolism were studied in fed rainbow trout (Oncorhynchus mykiss) held at 11.5-14 degrees and intraperitoneally…”
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11
Development of a short-term reproductive endocrine bioassay using steroid hormone and vitellogenin end points in the estuarine mummichog (Fundulus heteroclitus)
Published in Environmental toxicology and chemistry (01-05-2003)“…We have developed a short‐term gonadal recrudescence test with the estuarine mummichog (Fundulus heteroclitus) and determined endocrine end points sensitive to…”
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Effects of a model androgen (methyl testosterone) and a model anti-androgen (cyproterone acetate) on reproductive endocrine endpoints in a short-term adult mummichog ( Fundulus heteroclitus) bioassay
Published in Aquatic toxicology (28-04-2004)“…A short-term gonadal recrudescence bioassay using the mummichog ( Fundulus heteroclitus) was employed to examine the consequences of environmentally relevant…”
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In vivo implants of β-sitosterol cause reductions of reactive cholesterol pools in mitochondria isolated from gonads of male goldfish ( Carassius auratus)
Published in General and comparative endocrinology (01-12-2003)“…β-Sitosterol, a phytosterol found in high concentrations in pulp mill effluents, has been proposed as one of the causative agents for steroid depressions…”
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Influence of dietary lipid and carbohydrate levels and chronic 3,5,3'-triiodo-L-thyronine treatment on thyroid function in immature rainbow trout, Oncorhynchus mykiss
Published in General and comparative endocrinology (01-10-1990)“…The influence of varying dietary levels of nonprotein energy sources (lipid, L; carbohydrate, C) and 3,5,3'-triiodo-L-thyronine (T3) on thyroid function in…”
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15
Effects of a phytosterol mixture on male fish plasma lipoprotein fractions and testis P450scc activity
Published in General and comparative endocrinology (01-02-2003)“…Plant sterols (phytosterols) have been identified as one potential source of reproductive effects in fish living downstream of pulp mills. β-Sitosterol, the…”
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Endocrine responses of Fundulus heteroclitus to effluent from a bleached-kraft pulp mill before and after installation of reverse osmosis treatment of a waste stream
Published in Environmental toxicology and chemistry (01-11-2000)“…Implementation of process changes on the nonbleaching side of bleached kraft pulp mill (BKPM) operations has increased in recent years to maximize resource use…”
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Rapid carbon turnover during growth of Atlantic salmon (Salmo salar) smolts in sea water, and evidence for reduced food consumption by growth-stunts
Published in Hydrobiologia (01-10-2004)“…Wild Atlantic salmon smolts were captured during spring out-migration in the Northwest Miramichi River, New Brunswick, Canada, and placed on an isotopically…”
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Thyroid hormone deiodinase systems in salmonids, and their involvement in the regulation of thyroidal status
Published in Fish Physiology and Biochemistry [FISH PHYSIOL. BIOCHEM.]. Vol. 11, no. 1-6. 1993 (01-07-1993)“…The trout thyroid secretes L-thyroxine (T4) which undergoes enzymatic deiodination in liver and other tissues. Based on mammalian studies, T4 outer-ring…”
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Utility of morphological abnormalities during early-life development of the estuarine mummichog, Fundulus heteroclitus, as an indicator of estrogenic and antiestrogenic endocrine disruption
Published in Environmental toxicology and chemistry (01-02-2004)“…To evaluate the use of morphological abnormalities for standard testing of endocrine‐disrupting substances (EDS), we tested the hypothesis that developmental…”
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Short-term treatment with testosterone increases plasma 3,5,3'-triiodo-L-thyronine and hepatic L-thyroxine 5'-monodeiodinase levels in arctic charr, Salvelinus alpinus
Published in General and comparative endocrinology (01-07-1988)“…Testosterone (T), methyl testosterone (MT), and testosterone propionate (TP) (0.5 mg/100 g body wt in 40 microliter peanut oil) or peanut oil alone were…”
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