Search Results - "MACLAREN, N."

Passive surveillance of United Kingdom bats for lyssaviruses (2005–2015) by WISE, E. L., MARSTON, D. A., BANYARD, A. C., GOHARRIZ, H., SELDEN, D., MACLAREN, N., GODDARD, T., JOHNSON, N., MCELHINNEY, L. M., BROUWER, A., AEGERTER, J.N., SMITH, G.C., HORTON, D. L., BREED, A. C., FOOKS, A.R.

“…Passive surveillance for lyssaviruses in UK bats has been ongoing since 1987 and has identified 13 cases of EBLV-2 from a single species; Myotis daubentonii…”
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Association of diabetes mellitus and chronic hepatitis C virus infection by Mason, Andrew L., Lau, Johnson Y., Hoang, Nicole, Qian, KePing, Alexander, Graeme J., Xu, Lizhe, Guo, Linsheng, Jacob, Sheraj, Regenstein, Fredric G., Zimmerman, Robert, Everhart, James E., Wasserfall, Clive, Maclaren, Noel K., Perrillo, Robert P.

“…While patients with liver disease are known to have a higher prevalence of glucose intolerance, preliminary studies suggest that hepatitis C virus (HCV)…”
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The Pathogenesis of Insulin-Dependent Diabetes Mellitus by Atkinson, Mark A, Maclaren, Noel K

“…Insulin-dependent diabetes mellitus (IDDM) is a chronic disorder that results from autoimmune destruction of the insulin-producing pancreatic beta cells. Much…”
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Autoimmunity and Diabetes by Kukreja, Anjli, Maclaren, Noel K

“…The face of immune-mediated (type 1) diabetes is changing. No longer considered a disease confined to childhood, the incidence rate in Western countries is…”
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Insulin-Dependent Diabetes Mellitus (IDDM) Is Associated with CTLA4 Polymorphisms in Multiple Ethnic Groups by Marron, Michele P., Raffel, Leslie J., Garchon, Henri-Jean, Jacob, Chaim O., Serrano-Rios, Manuel, Martinez Larrad, Maria T., Teng, Wei-Ping, Park, Yongsoo, Zhang, Zhi-Xing, Goldstein, Darlene R., Tao, Yi-Wen, Beaurain, Genevieve, Bach, Jean-Francois, Huang, Hong-So, Luo, De-Fang, Zeidler, Adina, Rotter, Jerome I., Yang, Mark C. K., Modilevsky, Tamara, Maclaren, Noel K., She, Jin-Xiong

“…Linkage disequilibrium (association) analysis was used to evaluate a candidate region near the CTLA4/CD28 genes using a multi-ethnic collection of families…”
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IA-2, a Transmembrane Protein of the Protein Tyrosine Phosphatase Family, is a Major Autoantigen in Insulin-Dependent Diabetes Mellitus by Lan, Michael S., Wasserfall, Clive, Maclaren, Noel K., Notkins, Abner Louis

“…IA-2 is a 105,847 Da transmembrane protein that belongs to the protein tyrosine phosphatase family. Immunoperoxidase staining with antibody raised against IA-2…”
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Current cases in which epitope mimicry is considered as a component cause of autoimmune disease: immune-mediated (type 1) diabetes by Kukreja, A, Maclaren, N K

“…Autoimmune diseases result from a combination of genetic, immunologic, hormonal, and environmental factors. Infectious agents may induce the breakdown of…”
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HLA-DRB108, DRB103/DRB30101, and DRB30202 Are Susceptibility Genes for Graves’ Disease in North American Caucasians, Whereas DRB107 Is Protective by Chen, Qiao-Yi, Huang, Wei, She, Jin-Xiong, Baxter, Felicia, Volpe, Robert, Maclaren, Noel K

“…ABSTRACTGraves’ disease is known to be HLA-D associated; however, the primary loci involved remain unclear. We examined HLA genotypes of DRB1 and DQB1 plus…”
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The role of tyrosinase in autoimmune vitiligo by Song, Y H, Connor, E, Li, Y, Zorovich, B, Balducci, P, Maclaren, N

“…Vitiligo is a common depigmenting skin disease, associated with certain autoimmune endocrinopathies, and autoantibodies to several antigens can be found in…”
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Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes by Atkinson, M A, Kaufman, D L, Campbell, L, Gibbs, K A, Shah, S C, Bu, D F, Erlander, M G, Tobin, A J, Maclaren, N K

“…Insulin-dependent diabetes is characterised by autoantibodies to several pancreatic-islet-cell antigens, including glutamate decarboxylase. We measured the…”
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Islet cell autoantigens in insulin-dependent diabetes by ATKINSON, M. A, MACLAREN, N. K

“…A burgeoning number of antigenic targets of the islet cell autoimmunity in IDD have been identified, and more can be anticipated through improved methods for…”
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Limited genetic susceptibility to severe Graves' ophthalmopathy: no role for CTLA-4 but evidence for an environmental etiology by Villanueva, R, Inzerillo, A M, Tomer, Y, Barbesino, G, Meltzer, M, Concepcion, E S, Greenberg, D A, MacLaren, N, Sun, Z S, Zhang, D M, Tucci, S, Davies, T F

“…Graves' disease (GD) is an autoimmune thyroid disease (AITD) characterized by hyperthyroidism and by the occurrence of a distinctive ophthalmopathy…”
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Although DR3-DQB10201 may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB10302 haplotype is implicated only in β-cell autoimmunity by HUANG, W, CONNOR, E, DELA ROSA, T, MUIR, A, SCHATZ, D, SILVERSTEIN, J, CROCKETT, S, SHE, J.-X, MACLAREN, N. K

“…Human leukocyte antigen (HLA)-DRB1 and -DQB1 alleles were analyzed using a PCR-based sequence-specific priming technique in 16 patients with autoimmune…”
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Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27 by DE-FANG LUO, BUI, M. M, MUIR, A, MACLAREN, N. K, THOMSON, G, JIN-XIONG SHE

“…Affected-sib-pair analyses were performed using 104 Caucasian families to map genes that predispose to insulin-dependent diabetes mellitus (IDDM). We have…”
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Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy by Atkinson, M. A., Maclaren, N. K., Luchetta, R.

“…Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy. M A Atkinson , N K Maclaren and R Luchetta Department of Pathology, College of…”
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Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus by The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

“…Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus The Expert Committee on the Diagnosis and Classification of Diabetes…”
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64,000 Mr autoantibodies as predictors of insulin-dependent diabetes by Atkinson, M A, Maclaren, N K, Scharp, D W, Lacy, P E, Riley, W J

“…The occurrence of autoantibodies to an islet-cell protein of 64,000 Mr (64KA) was examined in relation to development of insulin-dependent diabetes. 64KA were…”
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Multiple autoantibodies as predictors of Type 1 diabetes in a general population by Maclaren, N K, Lan, M S, Schatz, D, Malone, J, Notkins, A L, Krischer, J

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A Prospective Study of the Development of Diabetes in Relatives of Patients with Insulin-Dependent Diabetes by Riley, William J, Maclaren, Noel K, Krischer, Jeffrey, Spillar, Rebecca P, Silverstein, Janet H, Schatz, Desmond A, Schwartz, Sherwin, Malone, John, Shah, Shirish, Vadheim, Constance, Rotter, Jerome I

“…THAT insulin-dependent diabetes mellitus (IDDM) is an autoimmune disorder is now generally accepted. Autoantibodies to cytoplasmic antigens in the pancreatic…”
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Confirmation of Three Susceptibility Genes to Insulin-Dependent Diabetes Mellitus: IDDM4, IDDM5 and IDDM8 by Luo, De-Fang, Buzzetti, Raffaella, Rotter, Jerome I., Maclaren, Noel K., Raffel, Leslie J., Nisticô, Lorenza, Giovannini, Claudio, Pozzilli, Paolo, Thomson, Glenys, She, Jin-Xiong

“…Previous genome-wide mapping studies have provided suggestive linkage evidence for several novel susceptibility loci responsible for insulin-dependent diabetes…”
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