Search Results - "MACKAY, Ian"
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A large-scale pedigree resource of wheat reveals evidence for adaptation and selection by breeders
Published in PLoS biology (01-02-2019)“…Information on crop pedigrees can be used to help maximise genetic gain in crop breeding and allow efficient management of genetic resources. We present a…”
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MERS coronavirus: diagnostics, epidemiology and transmission
Published in Virology journal (22-12-2015)“…The first known cases of Middle East respiratory syndrome (MERS), associated with infection by a novel coronavirus (CoV), occurred in 2012 in Jordan but were…”
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Understanding the classics: the unifying concepts of transgressive segregation, inbreeding depression and heterosis and their central relevance for crop breeding
Published in Plant biotechnology journal (01-01-2021)“…Summary Transgressive segregation and heterosis are the reasons that plant breeding works. Molecular explanations for both phenomena have been suggested and…”
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The evolving battle between yellow rust and wheat: implications for global food security
Published in Theoretical and applied genetics (01-03-2022)“…Wheat ( Triticum aestivum L.) is a global commodity, and its production is a key component underpinning worldwide food security. Yellow rust, also known as…”
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Using Genetic Distance to Infer the Accuracy of Genomic Prediction
Published in PLoS genetics (02-09-2016)“…The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest;…”
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Genome‐wide association mapping of Hagberg falling number, protein content, test weight, and grain yield in U.K. wheat
Published in Crop science (01-05-2022)“…Association mapping using crop cultivars allows identification of genetic loci of direct relevance to breeding. Here, 150 U.K. wheat (Triticum aestivum L.)…”
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Limited haplotype diversity underlies polygenic trait architecture across 70 years of wheat breeding
Published in Genome Biology (06-05-2021)“…Selection has dramatically shaped genetic and phenotypic variation in bread wheat. We can assess the genomic basis of historical phenotypic changes, and the…”
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Evolving Trends in Female to Male Incidence and Male Mortality of Primary Biliary Cholangitis
Published in Scientific reports (19-05-2016)“…Primary biliary cholangitis (PBC) has been regarded as female-predominant without evidence of gender difference in survival. We aimed to compare the overall…”
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Investigating the genetic control of plant development in spring barley under speed breeding conditions
Published in Theoretical and applied genetics (01-05-2024)“…Key message This study found that the genes, PPD-H1 and ELF3, control the acceleration of plant development under speed breeding, with important implications…”
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From mutations to MAGIC: resources for gene discovery, validation and delivery in crop plants
Published in Current opinion in plant biology (01-04-2008)“…The dissection of gene-trait associations and its translation into practice through plant breeding is a central aspect of modern plant biology. The…”
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Sequence-based marker development in wheat: Advances and applications to breeding
Published in Biotechnology advances (01-09-2012)“…In the past two decades, the wheat community has made remarkable progress in developing molecular resources for breeding. A wide variety of molecular tools has…”
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Genomic prediction unifies animal and plant breeding programs to form platforms for biological discovery
Published in Nature genetics (01-09-2017)“…Wayne Powell and colleagues compare the different tools and approaches used by the plant breeding community versus the animal breeding community for crop and…”
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Identification of a novel polyomavirus from patients with acute respiratory tract infections
Published in PLoS pathogens (01-05-2007)“…We report the identification of a novel polyomavirus present in respiratory secretions from human patients with symptoms of acute respiratory tract infection…”
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The causes of primary biliary cirrhosis: Convenient and inconvenient truths
Published in Hepatology (Baltimore, Md.) (01-02-2008)“…The most difficult issue in autoimmunity remains etiology. Although data exist on effector mechanisms in many autoimmune diseases, the underlying cause or…”
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Assessment of Local Mosquito Species Incriminates Aedes aegypti as the Potential Vector of Zika Virus in Australia
Published in PLoS neglected tropical diseases (19-09-2016)“…Within the last 10 years Zika virus (ZIKV) has caused unprecedented epidemics of human disease in the nations and territories of the western Pacific and South…”
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Multi-parent populations in crops: a toolbox integrating genomics and genetic mapping with breeding
Published in Heredity (01-12-2020)“…Crop populations derived from experimental crosses enable the genetic dissection of complex traits and support modern plant breeding. Among these, multi-parent…”
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A highly recombined, high‐density, eight‐founder wheat MAGIC map reveals extensive segregation distortion and genomic locations of introgression segments
Published in Plant biotechnology journal (01-06-2016)“…Summary Multiparent Advanced Generation Intercross (MAGIC) mapping populations offer unique opportunities and challenges for marker and QTL mapping in crop…”
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Wheat genetic loci conferring resistance to stripe rust in the face of genetically diverse races of the fungus Puccinia striiformis f. sp. tritici
Published in Theoretical and applied genetics (01-01-2022)“…Key message Analysis of a wheat multi-founder population identified 14 yellow rust resistance QTL. For three of the four most significant QTL, haplotype…”
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Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd
Published in Virus research (16-04-2015)“…•Middle East respiratory syndrome coronavirus (MERS-CoV) is a severe, mild or subclinical infection.•MERS is most severe among older men with…”
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Autoimmune liver serology:Current diagnostic and clinical challenges
Published in World journal of gastroenterology : WJG (07-06-2008)“…Liver-related autoantibodies are crucial for the correct diagnosis and classification of autoimmune liver diseases(AiLD),namely autoimmune hepatitis types 1…”
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