Search Results - "MACK, R"

The Itch–Scratch Cycle: A Neuroimmune Perspective by Mack, Madison R., Kim, Brian S.

“…Relentless, repetitive itching and scratching is a debilitating feature of many chronic inflammatory skin disorders such as atopic dermatitis. While well known…”
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Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch by Meixiong, James, Anderson, Michael, Limjunyawong, Nathachit, Sabbagh, Mark F., Hu, Eric, Mack, Madison R., Oetjen, Landon K., Wang, Fang, Kim, Brian S., Dong, Xinzhong

“…Classical itch studies have focused on immunoglobulin E (IgE)-mediated mast cell activation and histamine release. Recently, members of the Mas-related…”
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Hyperspectral imagery to monitor crop nutrient status within and across growing seasons by Liu, Nanfeng, Townsend, Philip A., Naber, Mack R., Bethke, Paul C., Hills, William B., Wang, Yi

“…Imaging spectroscopy provides the opportunity to monitor nutrient status of vegetation. In crops, prior studies have generally been limited in scope, either to…”
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Performance of a Genomic Sequencing Classifier for the Preoperative Diagnosis of Cytologically Indeterminate Thyroid Nodules by Patel, Kepal N, Angell, Trevor E, Babiarz, Joshua, Barth, Neil M, Blevins, Thomas, Duh, Quan-Yang, Ghossein, Ronald A, Harrell, R Mack, Huang, Jing, Kennedy, Giulia C, Kim, Su Yeon, Kloos, Richard T, LiVolsi, Virginia A, Randolph, Gregory W, Sadow, Peter M, Shanik, Michael H, Sosa, Julie A, Traweek, S Thomas, Walsh, P Sean, Whitney, Duncan, Yeh, Michael W, Ladenson, Paul W

“…Use of next-generation sequencing of RNA and machine learning algorithms can classify the risk of malignancy in cytologically indeterminate thyroid nodules to…”
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AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ASSOCIAZIONE MEDICI ENDOCRINOLOGI MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND MANAGEMENT OF THYROID NODULES--2016 UPDATE by Gharib, Hossein, Papini, Enrico, Garber, Jeffrey R, Duick, Daniel S, Harrell, R Mack, Hegedüs, Laszlo, Paschke, Ralf, Valcavi, Roberto, Vitti, Paolo

“…Thyroid nodules are detected in up to 50 to 60% of healthy subjects. Most nodules do not cause clinically significant symptoms, and as a result, the main…”
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The Paraventricular Nucleus of the Thalamus Is an Important Node in the Emotional Processing Network by Barson, Jessica R, Mack, Nancy R, Gao, Wen-Jun

“…The paraventricular nucleus of the thalamus (PVT) has for decades been acknowledged to be an important node in the limbic system, but studies of emotional…”
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Surgical utility of Afirma: effects of high cancer prevalence and oncocytic cell types in patients with indeterminate thyroid cytology by Harrell, R Mack, Bimston, David N

“…The Afirma Gene Expression Classifier (GEC) molecular marker assay was developed for the purpose of improving surgical decision-making with indeterminate…”
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Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch by Oetjen, Landon K., Mack, Madison R., Feng, Jing, Whelan, Timothy M., Niu, Haixia, Guo, Changxiong J., Chen, Sisi, Trier, Anna M., Xu, Amy Z., Tripathi, Shivani V., Luo, Jialie, Gao, Xiaofei, Yang, Lihua, Hamilton, Samantha L., Wang, Peter L., Brestoff, Jonathan R., Council, M. Laurin, Brasington, Richard, Schaffer, András, Brombacher, Frank, Hsieh, Chyi-Song, Gereau, Robert W., Miller, Mark J., Chen, Zhou-Feng, Hu, Hongzhen, Davidson, Steve, Liu, Qin, Kim, Brian S.

“…Mammals have evolved neurophysiologic reflexes, such as coughing and scratching, to expel invading pathogens and noxious environmental stimuli. It is well…”
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Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease by Mottawea, Walid, Chiang, Cheng-Kang, Mühlbauer, Marcus, Starr, Amanda E., Butcher, James, Abujamel, Turki, Deeke, Shelley A., Brandel, Annette, Zhou, Hu, Shokralla, Shadi, Hajibabaei, Mehrdad, Singleton, Ruth, Benchimol, Eric I., Jobin, Christian, Mack, David R., Figeys, Daniel, Stintzi, Alain

“…Intestinal microbial dysbiosis is associated with Crohn’s disease (CD). However, the mechanisms leading to the chronic mucosal inflammation that characterizes…”
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Granivory of invasive, naturalized, and native plants in communities differentially susceptible to invasion by Connolly, B. M, Pearson, D. E, Mack, R. N

“…Seed predation is an important biotic filter that can influence abundance and spatial distributions of native species through differential effects on…”
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Incidence, Outcomes, and Health Services Burden of Very Early Onset Inflammatory Bowel Disease by Benchimol, Eric I, Mack, David R, Nguyen, Geoffrey C, Snapper, Scott B, Li, Wenbin, Mojaverian, Nassim, Quach, Pauline, Muise, Aleixo M

“…Background & Aims The Paris pediatric modification of the Montreal classification defines very early onset inflammatory bowel disease (VEO-IBD) as a form of…”
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Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity by Brestoff, Jonathan R., Wilen, Craig B., Moley, John R., Li, Yongjia, Zou, Wei, Malvin, Nicole P., Rowen, Marina N., Saunders, Brian T., Ma, Hongming, Mack, Madison R., Hykes, Barry L., Balce, Dale R., Orvedahl, Anthony, Williams, Jesse W., Rohatgi, Nidhi, Wang, Xiaoyan, McAllaster, Michael R., Handley, Scott A., Kim, Brian S., Doench, John G., Zinselmeyer, Bernd H., Diamond, Michael S., Virgin, Herbert W., Gelman, Andrew E., Teitelbaum, Steven L.

“…Recent studies suggest that mitochondria can be transferred between cells to support the survival of metabolically compromised cells. However, whether…”
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The Neuroimmune Axis in Skin Sensation, Inflammation, and Immunity by Trier, Anna M, Mack, Madison R, Kim, Brian S

“…Although connections between the immune and nervous systems have long been recognized, the precise mechanisms that underlie this relationship are just starting…”
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Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population-Based Provincial Health Administrative Databases by Benchimol, Eric I, Bernstein, Charles N, Bitton, Alain, Carroll, Matthew W, Singh, Harminder, Otley, Anthony R, Vutcovici, Maria, El-Matary, Wael, Nguyen, Geoffrey C, Griffiths, Anne M, Mack, David R, Jacobson, Kevan, Mojaverian, Nassim, Tanyingoh, Divine, Cui, Yunsong, Nugent, Zoann J, Coulombe, Janie, Targownik, Laura E, Jones, Jennifer L, Leddin, Desmond, Murthy, Sanjay K, Kaplan, Gilaad G

“…The incidence of pediatric-onset inflammatory bowel disease (IBD) is increasing worldwide. We used population-based health administrative data to determine…”
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Real-World Performance of the Afirma Genomic Sequencing Classifier (GSC)—A Meta-analysis by Nasr, Christian E, Andrioli, Massimiliano, Endo, Mayumi, Harrell, R Mack, Livhits, Masha J, Osakwe, Ibitoro, Polavarapu, Preethi, Siperstein, Allan, Wei, Shuanzeng, Zheng, Xingyu, Jiang, Ruochen, Hao, Yangyang, Huang, J I ng, Klopper, Joshua P, Kloos, Richard T, Kennedy, Giulia, Angell, Trevor E

“…Abstract Context The Afirma® GSC aids in risk stratifying indeterminate thyroid nodule cytology (ITN). The 2018 GSC validation study (VS) reported a…”
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Sensory TRP channels contribute differentially to skin inflammation and persistent itch by Feng, Jing, Yang, Pu, Mack, Madison R., Dryn, Dariia, Luo, Jialie, Gong, Xuan, Liu, Shenbin, Oetjen, Landon K., Zholos, Alexander V., Mei, Zhinan, Yin, Shijin, Kim, Brian S., Hu, Hongzhen

“…Although both persistent itch and inflammation are commonly associated with allergic contact dermatitis (ACD), it is not known if they are mediated by shared…”
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Aberrant maturation and connectivity of prefrontal cortex in schizophrenia—contribution of NMDA receptor development and hypofunction by Gao, Wen-Jun, Yang, Sha-Sha, Mack, Nancy R., Chamberlin, Linda A.

“…The neurobiology of schizophrenia involves multiple facets of pathophysiology, ranging from its genetic basis over changes in neurochemistry and…”
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A Subpopulation of Prefrontal Cortical Neurons Is Required for Social Memory by Xing, Bo, Mack, Nancy R., Guo, Kai-Ming, Zhang, Yu-Xiang, Ramirez, Billy, Yang, Sha-Sha, Lin, Li, Wang, Dong V., Li, Yan-Chun, Gao, Wen-Jun

“…The medial prefrontal cortex (mPFC) is essential for social behaviors, yet whether and how it encodes social memory remains unclear. We combined whole-cell…”
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Macrophage angiotensin II type 2 receptor triggers neuropathic pain by Shepherd, Andrew J., Mickle, Aaron D., Golden, Judith P., Mack, Madison R., Halabi, Carmen M., de Kloet, Annette D., Samineni, Vijay K., Kim, Brian S., Krause, Eric G., Gereau, Robert W., Mohapatra, Durga P.

“…Peripheral nerve damage initiates a complex series of structural and cellular processes that culminate in chronic neuropathic pain. The recent success of a…”
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STATISTICAL COMPARISON OF AFIRMA GSC AND AFIRMA GEC OUTCOMES IN A COMMUNITY ENDOCRINE SURGICAL PRACTICE: EARLY FINDINGS by Harrell, R Mack, Eyerly-Webb, Stephanie A, Golding, Allan C, Edwards, Courtney M, Bimston, David N

“…The Veracyte Afirma Gene Expression Classifier (GEC) has been the most widely used negative predictive value molecular classifier for indeterminate cytology…”
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