Search Results - "MACINTYRE, Alan"
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Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort
Published in PloS one (27-07-2011)“…It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease. This study…”
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Journal Article -
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Socio-economic status is associated with epigenetic differences in the pSoBid cohort
Published in International journal of epidemiology (01-02-2012)“…Epigenetic programming and epigenetic mechanisms driven by environmental factors are thought to play an important role in human health and ageing. Global DNA…”
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Journal Article -
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The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people
Published in Neuroscience letters (09-10-2006)“…Telomeres are nucleo-protein complexes that protect the ends of chromosomes. The telomeric DNA component shortens each time a somatic cell replicates,…”
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Vaginal Microbiome in Preterm Rupture of Membranes
Published in Obstetrics and gynecology clinics of North America (01-12-2020)“…There is an association between vaginal microbiota dysbiosis and preterm premature rupture of membranes (PPROM). In PPROM, reduced Lactobacillus spp abundance…”
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Microvesicles but Not Exosomes from Pathfinder Cells Stimulate Functional Recovery of the Pancreas in a Mouse Streptozotocin-Induced Diabetes Model
Published in Rejuvenation research (01-06-2016)“…Pathfinder cells (PCs), a novel cell type derived from the pancreas of adult rats, have been demonstrated to stimulate recovery of tissue structure and…”
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Heterotopic Ossification After Blunt Abdominal Trauma
Published in The Journal of trauma, injury, infection, and critical care (01-12-2008)Get full text
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Pathfinder cells provide a novel therapeutic intervention for acute kidney injury
Published in Rejuvenation research (01-02-2013)“…Pathfinder cells (PCs) are a novel class of adult-derived cells that facilitate functional repair of host tissue. We used rat PCs to demonstrate that they…”
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Simvastatin inhibits lymphocyte function in normal subjects and patients with cardiovascular disease
Published in Atherosclerosis (01-08-2004)“…HMG-CoA reductase inhibitors (statins) block the mevalonate pathway, preventing biosynthesis of cholesterol and isoprenoids. We investigated the effect of…”
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Pancreatic-derived pathfinder cells enable regeneration of critically damaged adult pancreatic tissue and completely reverse streptozotocin-induced diabetes
Published in Rejuvenation research (01-04-2011)“…We demonstrate that intravenous delivery of human, or rat, pancreas-derived pathfinder (PDP) cells can totally regenerate critically damaged adult tissue and…”
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Development of In Situ Hybridisation for Cytokines in Rejecting and Tolerant Cardiac Allografts
Published 01-01-1998“…An In situ Hybridisation method was developed and utilised to evaluate and pinpoint the cellular presence of IL2 and IL4 mRNA transcripts produced by Th 1 and…”
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Dissertation -
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Princess's car may have hit Fiat before fatal crash
Published in Times (London, England : 1788) (18-09-1997)Get full text
Newspaper Article