Search Results - "MACGROGAN, Gaëtan"
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Terahertz refractive index-based morphological dilation for breast carcinoma delineation
Published in Scientific reports (19-03-2021)“…This paper reports investigations led on the combination of the refractive index and morphological dilation to enhance performances towards breast tumour…”
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2
Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group
Published in Modern pathology (01-09-2015)“…Neoadjuvant systemic therapy is being used increasingly in the treatment of early-stage breast cancer. Response, in the form of pathological complete response,…”
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3
Solid-type adenoid cystic carcinoma of the breast, a distinct molecular entity enriched in NOTCH and CREBBP mutations
Published in Modern pathology (01-06-2020)“…Adenoid cystic carcinoma (ACC) of the breast with a predominant solid pattern is difficult to diagnose with certainty and differentiate from more common…”
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Impact of the COVID-19 lockdown in France on the diagnosis and staging of breast cancers in a tertiary cancer centre
Published in European radiology (01-03-2022)“…Objectives Due to COVID-19, a lockdown took place between March 17 and May 1, 2020, in France. This study evaluates the impact of the lockdown on the diagnosis…”
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SOX10, GATA3, GCDFP15, Androgen Receptor, and Mammaglobin for the Differential Diagnosis Between Triple-negative Breast Cancer and TTF1-negative Lung Adenocarcinoma
Published in The American journal of surgical pathology (01-03-2019)“…Triple-negative breast cancer (TNBC) patients have an increased risk of developing visceral metastases and other primary nonbreast cancers, particularly lung…”
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Variables with time-varying effects and the Cox model: some statistical concepts illustrated with a prognostic factor study in breast cancer
Published in BMC medical research methodology (16-03-2010)“…The Cox model relies on the proportional hazards (PH) assumption, implying that the factors investigated have a constant impact on the hazard - or risk - over…”
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Residual cancer burden index and tumor-infiltrating lymphocyte subtypes in triple-negative breast cancer after neoadjuvant chemotherapy
Published in Breast cancer research and treatment (2020)“…Purpose There is a need to refine the prognosis of triple-negative breast cancer (TNBC) patients after neoadjuvant chemotherapy (NAC) and to study the…”
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8
MED12 alterations in both human benign and malignant uterine soft tissue tumors
Published in PloS one (29-06-2012)“…The relationship between benign uterine leiomyomas and their malignant counterparts, i.e. leiomyosarcomas and smooth muscle tumors of uncertain malignant…”
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Pilot study of freshly excised breast tissue response in the 300-600 GHz range
Published in Biomedical optics express (01-07-2018)“…The failure to accurately define tumor margins during breast conserving surgery (BCS) results in a 20% re-excision rate. The present paper reports the…”
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10
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers
Published in Nature communications (13-07-2016)“…HER2-positive breast cancer has long proven to be a clinically distinct class of breast cancers for which several targeted therapies are now available…”
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Terahertz near-field microscopy of ductal carcinoma in situ (DCIS) of the breast
Published in JPhys photonics (01-10-2020)“…Imaging with terahertz (THz) waves has been expected as a non-invasive/non-staining visualization tool for breast cancer margins during surgeries. Breast…”
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Comprehensive analysis of PTEN status in breast carcinomas
Published in International journal of cancer (15-07-2013)“…PTEN plays a well‐established role in the negative regulation of the PI3K pathway, which is frequently activated in several cancer types, including breast…”
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13
Phenotypic discordance between primary and metastatic breast cancer in the large-scale real-life multicenter French ESME cohort
Published in NPJ breast cancer (16-04-2021)“…Expression of hormone receptor (HR) for estrogens (ER) and progesterone (PR) and HER2 remains the cornerstone to define the therapeutic strategy for breast…”
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Label-Free Observation of Micrometric Inhomogeneity of Human Breast Cancer Cell Density Using Terahertz Near-Field Microscopy
Published in Photonics (01-05-2021)“…Terahertz-light imaging is attracting great attention as a new approach in non-invasive/non-staining biopsy of cancerous tissues. Positively, terahertz light…”
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15
Scanning point terahertz source microscopy of unstained comedo ductal carcinoma in situ
Published in Optics continuum (15-03-2022)“…Terahertz imaging is an emerging candidate to diagnose breast cancers in a label-free manner. However, detailed terahertz analysis of early stage breast…”
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Combined tumor genomic profiling and exome sequencing in a breast cancer family implicates ATM in tumorigenesis: A proof of principle study
Published in Genes chromosomes & cancer (01-11-2017)“…Familial breast cancers (BCs) account for 10%‐20% of all diagnosed BCs, yet only 20% of such tumors arise in the context of a germline mutation in known tumor…”
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Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity
Published in Breast cancer research : BCR (01-01-2007)“…Typical medullary breast carcinoma (MBC) has recently been recognized to be part of the basal-like carcinoma spectrum, a feature in agreement with the high…”
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Neoadjuvant endocrine treatment in breast cancer: analysis of daily practice in large cancer center to facilitate decision making
Published in The American journal of surgery (01-11-2014)“…Abstract Background To examine outcomes of neoadjuvant endocrine therapy in daily practice to inform decision making. Methods We retrospectively selected 204…”
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Validation of death prediction after breast cancer relapses using joint models
Published in BMC medical research methodology (01-04-2015)“…Cancer relapses may be useful to predict the risk of death. To take into account relapse information, the Landmark approach is popular. As an alternative, we…”
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20
Lymph node involvement in epithelial ovarian cancer: sites and risk factors in a series of 355 patients
Published in International journal of gynecological cancer (01-11-2009)“…To perform a cartography of lymph node metastases in epithelial ovarian cancer and to determine predictive factors of lymph node metastases. The charts of 355…”
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