Search Results - "MACEY, M. G."

Immunolocalization of protease‐activated receptor‐2 in skin: receptor activation stimulates interleukin‐8 secretion by keratinocytes in vitro by HOU, L., KAPAS, S., CRUCHLEY, A. T., MACEY, M. G., HARRIOTT, P., CHINNI, C., STONE, S. R., HOWELLS, G. L.

“…The protease‐activated receptor‐2 (PAR‐2) is a seven transmembrane domain receptor related to the thrombin receptor, which is activated in vitro by cleavage by…”
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Effect on polymorphonuclear cell function of a human-specific cytotoxin, intermedilysin, expressed by Streptococcus intermedius by MACEY, M. G, WHILEY, R. A, MILLER, L, NAGAMUNE, H

“…Streptococcus intermedius is a member of the normal flora of the mouth but is also an opportunistic pathogen associated with purulent infections at oral and…”
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Flow cytometric analysis of microparticle phenotype and their role in thrombin generation by Macey, M. G., Enniks, N., Bevan, S.

“…Background: Microparticles may be generated from a number of cell types and are known to play a role in haemostasis by a variety of mechanisms. We investigated…”
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THE PROTEASE‐ACTIVATED RECEPTORS AND THEIR CELLULAR EXPRESSION AND FUNCTION IN BLOOD‐RELATED CELLS by HOU, L, HOWELLS, G. L, KAPAS, S, MACEY, M. G

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Platelet activation and endogenous thrombin potential in pre-eclampsia by Macey, M.G, Bevan, S, Alam, S, Verghese, L, Agrawal, S, Beski, S, Thuraisingham, R, MacCallum, P.K

“…Abstract Introduction Platelets and the coagulation system may be involved in the pathogenesis of pre-eclampsia. We investigated whether platelet and…”
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Effects of cell purification methods on CD11b and l-selectin expression as well as the adherence and activation of leucocytes by Macey, M.G., McCarthy, D.A., Vordermeier, S., Newland, A.C., Brown, K.A.

“…This study investigated the effects of commonly used procedures for the isolation of leucocytes from human blood in comparison with cells in whole blood on the…”
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The role of natural killer T (NKT) cells in immune thrombocytopenia: is strong in vitro NKT cell activity related to the development of remission? by Johansson, U., Macey, M. G., Kenny, D., Provan, A. B., Newland, A. C.

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Intra-epithelial subpopulations of T lymphocytes and Langerhans cells in oral lichen planus by Walton, L. J., Macey, M. G., Thornhill, M. H., Farthing, P. M.

“…This study has addressed the question of whether there is selective recruitment and distribution of intra‐epithelial leucocytes in lesions of oral lichen…”
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Protease-activated receptors and their role in IL-6 and NF-IL-6 expression in human gingival fibroblasts by Hou, L., Ravenall, S., Macey, M. G., Harriott, P., Kapas, S., Howells, G. L.

“…The serine protease thrombin is formed at sites of coagulation and inflammation and has been shown to have important proinflammatory cellular effects relevant…”
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Protein A immunoadsorption in chronic refractory ITP reverses increased platelet activation but fails to achieve sustained clinical benefit by CAHILL, M. R, MACEY, M. G, CAVENAGH, J. D, NEWLAND, A. C

“…Adults with chronic relapsing ITP present a difficult therapeutic challenge. The ongoing antibody‐ mediated platelet destruction in this group might be…”
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Minimal residual disease detection with tumor-specific CD160 correlates with event-free survival in chronic lymphocytic leukemia by Farren, T W, Giustiniani, J, Fanous, M, Liu, F, Macey, M G, Wright, F, Prentice, A, Nathwani, A, Agrawal, S G

“…In chronic lymphocytic leukemia (CLL), the detection of minimal residual disease (MRD) correlates with outcome in the trial setting. However, MRD assessment…”
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A simple flow cytometric procedure for the determination of surface antigens on unfixed leucocytes in whole blood by McCarthy, D A, Macey, M G

“…A novel procedure has been developed for the quantitation by flow cytometry of function-associated antigens on neutrophils and monocytes in unlysed, unfixed,…”
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von Willebrand factor release and P-selectin expression is stimulated by thrombin and trypsin but not IL-1 in cultured human endothelial cells by Collins, P W, Macey, M G, Cahill, M R, Newland, A C

“…The stimulated release of von Willebrand factor (vWF) from endothelial cells by secretagogues such as thrombin is associated with the translocation of…”
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Fixation with formaldehyde induces expression of activation dependent platelet membrane glycoproteins, P selectin (CD62) and GP53 (CD63) by Cahill, M R, Macey, M G, Newland, A C

“…Platelet activation in vivo is important in the pathogenesis of thrombosis. Accurate measurement is difficult due to artefactual in vitro preparation related…”
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Comparative expression of major histocompatibility complex (MHC) antigens on CD5 + and CD5 − B cells in patients with chronic lymphocytic leukaemia (CLL) by Nouri, A.M.E, Smith, S, Newland, A.C, Macey, M.G

“…The aim of this study was to investigate the expression of major histocompatibility complex (MHC) antigens on CD5 + and CD5 − B cells of 13 patients with…”
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Thymic function in adults: evidence derived from immune recovery patterns following myeloablative chemotherapy and stem cell infusion by Cavenagh, J. D., Milne, T. M., Macey, M. G., Newland, A. C.

“…We studied 45 patients aged 14–66 years who had undergone stem cell transplantation for a variety of malignant conditions at least 12 months previously…”
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Mitochondrial electron transport chain activity, but not ATP synthesis, is required for drug‐induced apoptosis in human leukaemic cells: a possible novel mechanism of regulating drug resistance by Jia, Li, Allen, Paul D., Macey, Marion G., Grahn, Michael F., Newland, Adrian C., Kelsey, Stephen M.

“…There is increasing evidence for an association between mitochondrial function and susceptibility to apoptosis. It has been shown that the…”
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CD4 and CD8 subpopulation changes during high dose intravenous immunoglobulin treatment by Macey, M G, Newland, A C

“…High doses of immunoglobulin, when given intravenously (IVIgG), influence lymphocyte subset numbers and function. T-lymphocytes may be subdivided into two…”
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Immune thrombocytopenia and Fc receptor-mediated phagocyte function by NEWLAND, A. C, MACEY, M. G

“…The response to intravenous immunoglobulin treatment (IVIG) is thought, in part, to be due to blockade of Fc receptor for IgG in the mononuclear phagocyte…”
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Expression of functional antigens on neutrophils. Effects of preparation by Macey, M G, Jiang, X P, Veys, P, McCarthy, D, Newland, A C

“…We have studied how different conditions of cell labelling and isolation affect the expression of five functional antigens on neutrophils from healthy…”
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