Search Results - "MACDONALD, D. R"

Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas by van den Bent, MJ, Prof, Wefel, JS, PhD, Schiff, D, MD, Taphoorn, MJB, Prof, Jaeckle, K, MD, Junck, L, MD, Armstrong, T, PhD, Choucair, A, MD, Waldman, AD, PhD, Gorlia, T, MSc, Chamberlain, M, MD, Baumert, BG, MD, Vogelbaum, MA, MD, Macdonald, DR, MD, Reardon, DA, MD, Wen, PY, Prof, Chang, SM, Prof, Jacobs, AH, Prof

“…Summary Although low-grade gliomas (LGG) have a less aggressive course than do high-grade gliomas, the outcome of these tumours is ultimately fatal in most…”
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Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma by WELLER, M, GORLIA, T, ROSSETTI, A. O, LACOMBE, D, MIRIMANOFF, R.-O, VECHT, C. J, STUPP, R, CAIRNCROSS, J. G, VAN DEN BENT, M. J, MASON, W, BELANGER, K, BRANDES, A. A, BOGDAHN, U, MACDONALD, D. R, FORSYTH, P

“…This analysis was performed to assess whether antiepileptic drugs (AEDs) modulate the effectiveness of temozolomide radiochemotherapy in patients with newly…”
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Evaluating networked drug checking services in Toronto, Ontario: study protocol and rationale by Maghsoudi, N, McDonald, K, Stefan, C, Beriault, D R, Mason, K, Barnaby, L, Altenberg, J, MacDonald, R D, Caldwell, J, Nisenbaum, R, Leece, P, Watson, T M, Tupper, K W, Kufner, L, Scheim, A I, Werb, D

“…The increasing incidence of fatal opioid overdose is a public health crisis in Canada. Given growing consensus that this crisis is related to the presence of…”
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Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas by Bauman, G S, Ino, Y, Ueki, K, Zlatescu, M C, Fisher, B J, Macdonald, D R, Stitt, L, Louis, D N, Cairncross, J G

“…Allelic loss of the short arm of chromosome 1 predicts radiographic response to chemotherapy and long overall survival times in patients with anaplastic…”
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Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas by Cairncross, J. Gregory, Ueki, Keisuke, Zlatescu, Magdelena C., Lisle, David K., Finkelstein, Dianne M., Hammond, Robert R., Silver, Jonathan S., Stark, Paul C., Macdonald, David R., Ino, Yasushi, Ramsay, David A., Louis, David N.

“…Background/Methods: Gliomas are common malignant neoplasms of the central nervous system. Among the major subtypes of gliomas, oligodendrogliomas are…”
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Tibial nailing using a suprapatellar rather than an infrapatellar approach significantly reduces anterior knee pain postoperatively: a multicentre clinical trial by MacDonald, D R W, Caba-Doussoux, P, Carnegie, C A, Escriba, I, ward, D P, Graf, M, Johnstone, A J

“…AimsThe aim of this study was to compare the incidence of anterior knee pain after antegrade tibial nailing using suprapatellar and infrapatellar surgical…”
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In-Flight Performance of the High Energy X-Ray Timing Experiment on the Rossi X-Ray Timing Explorer by Rothschild, R. E, Blanco, P. R, Gruber, D. E, Heindl, W. A, MacDonald, D. R, Marsden, D. C, Pelling, M. R, Wayne, L. R, Hink, P. L

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Phase I Study of Topotecan Plus Cranial Radiation for Glioblastoma Multiforme: Results of Radiation Therapy Oncology Group Trial 9507 by FISHER, Barbara J, SCOTT, C, MACDONALD, D. R, COUGHLIN, C, CURRAN, W. J

“…A phase I trial was conducted by the Radiation Therapy Oncology Group (RTOG) to determine the maximum-tolerated dose of topotecan that could be safely combined…”
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Phase II study of PX-866 in recurrent glioblastoma by Pitz, Marshall W, Eisenhauer, Elizabeth A, MacNeil, Mary V, Thiessen, Brian, Easaw, Jacob C, Macdonald, David R, Eisenstat, David D, Kakumanu, Ankineedu S, Salim, Muhammad, Chalchal, Haji, Squire, Jeremy, Tsao, Ming Sound, Kamel-Reid, Suzanne, Banerji, Shantanu, Tu, Dongsheng, Powers, Jean, Hausman, Diana F, Mason, Warren P

“…Glioblastoma (GBM) is the most aggressive malignancy of the central nervous system in adults. Increased activity of the phosphatidylinositol-3-OH kinase (PI3K)…”
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MULTI-WAVELENGTH COVERAGE OF STATE TRANSITIONS IN THE NEW BLACK HOLE X-RAY BINARY SWIFT J1910.2-0546 by Degenaar, N, Maitra, D, CACKETT, E M, Reynolds, M T, Miller, J M, Reis, R C, King, A L, Gultekin, K, Bailyn, C D, Buxton, M M, MacDonald, R K D, Fabian, A C, Fox, D B, RYKOFF, E S

“…Understanding how black holes accrete and supply feedback to their environment is one of the outstanding challenges of modern astrophysics. Swift J1910.2-0546…”
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Response criteria for phase II studies of supratentorial malignant glioma by Macdonald, D R, Cascino, T L, Schold, Jr, S C, Cairncross, J G

“…We suggest "new" response criteria for phase II studies of supratentorial malignant glioma and favor rigorous criteria similar to those in medical oncology,…”
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Villoglandular adenocarcinoma of the cervix: Clarity is needed on the histological definition for this difficult diagnosis by Macdonald, R.D., Kirwan, J., Hayat, K., Herrington, C.S., Shawki, H.

“…Villoglandular adenocarcinoma (VGA) of the cervix is reported as a variant of a cervical adenocarcinoma with a good prognosis. We present two cases…”
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Neoadjuvant procarbazine, CCNU, and vincristine for anaplastic and aggressive oligodendroglioma by PALEOLOGOS, N. A, MACDONALD, D. R, VICK, N. A, CAIRNCROSS, J. G

“…The authors reviewed the results of neoadjuvant (preradiation) procarbazine, CCNU, and vincristine chemotherapy for anaplastic oligodendrogliomas because,…”
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Clinical trial end points for high-grade glioma: the evolving landscape by Reardon, David A., Galanis, Evanthia, DeGroot, John F., Cloughesy, Timothy F., Wefel, Jeffrey S., Lamborn, Kathleen R., Lassman, Andrew B., Gilbert, Mark R., Sampson, John H., Wick, Wolfgang, Chamberlain, Marc C., Macdonald, David R., Mehta, Minesh P., Vogelbaum, Michael A., Chang, Susan M., Van den Bent, Martin J., Wen, Patrick Y.

“…To review the strengths and weaknesses of primary and auxiliary end points for clinical trials among patients with high-grade glioma (HGG). Recent advances in…”
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Cognitive functioning in long-term survivors of high-grade glioma by ARCHIBALD, Y. M, LUNN, D, RUTTAN, L. A, MACDONALD, D. R, DEL MAESTRO, R. F, BARR, H. W. K, PEXMAN, J. H. W, FISHER, B. J, GASPAR, L. E, CAIRNCROSS, J. G

“…In a pilot study, two groups of patients with malignant glioma underwent sequential neuropsychological evaluations after successful tumor treatment. Group 1…”
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Neurocytomas: Long-term experience of a single institution by Hallock, A., Hamilton, B., Ang, L. C., Tay, K. Y., Meygesi, J. F., Fisher, B. J., Watling, C. J., Macdonald, D. R., Bauman, G. S.

“…There is a lack of studies reporting on outcomes of control and treatment toxicities for neurocytomas. A 25-year retrospective review of a tertiary center's…”
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Neurologic complications of chemotherapy by Macdonald, D R

“…Neurotoxicity is a common and potential dose-limiting complication of cancer chemotherapy. For most agents, high-dose therapy, combination chemotherapy,…”
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Low-grade gliomas, mixed gliomas, and oligodendrogliomas by Macdonald, D R

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Primary leptomeningeal lymphoma : report of 9 cases, diagnosis with immunocytochemical analysis, and review of the literature by LACHANCE, D. H, O'NEILL, B. P, MACDONALD, D. R, JAECKLE, K. A, WITZIG, T. E, LI, C.-Y, POSNER, J. B

“…We describe 9 patients who presented with a neoplastic meningitis of lymphomatous origin. No evidence of parenchymal central nervous system or systemic tumor…”
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Selection bias, survival, and brachytherapy for glioma by FLORELL, R. C, MACDONALD, D. R, IRISHI, W. D, BERNSTEIN, M, LIEBEL, S. A, GUTIN, P. H, CAIRNCROSS, J. G

“…Interstitial irradiation is a promising treatment for malignant glioma. Longer than expected survival periods following treatment of recurrent tumor have led…”
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