Search Results - "MACDONALD, B. R"

Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow by HUGHES, D. E, MACDONALD, B. R, RUSSELL, R. G. G, GOWEN, M

“…Bisphosphonates inhibit bone resorption in vivo and in vitro by unknown mechanisms. The effect of bisphosphonates on the formation of osteoclasts from their…”
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1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow by ROODMAN, G. D, IBBOTSON, K. J, MACDONALD, B. R, KUEHL, T. J, MUNDY, G. R

“…1,25-Dihydroxyvitamin D3 induces cells derived from mononuclear phagocytes such as HL-60 and U937 to differentiate to macrophage-like cells and causes alveolar…”
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Lighting up the Senses: FM1-43 Loading of Sensory Cells through Nonselective Ion Channels by Meyers, Jason R, MacDonald, Richard B, Duggan, Anne, Lenzi, David, Standaert, David G, Corwin, Jeffrey T, Corey, David P

“…We describe a novel mechanism for vital fluorescent dye entry into sensory cells and neurons: permeation through ion channels. In addition to the slow…”
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Formation of multinucleated cells that respond to osteotropic hormones in long term human bone marrow cultures by MacDonald, B R, Takahashi, N, McManus, L M, Holahan, J, Mundy, G R, Roodman, G D

“…Studies of osteoclasts and their precursors in normal and pathological states have been severely hampered by the lack of an in vitro system for forming…”
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Parathyroid hormone stimulates the proliferation of cells derived from human bone by MacDonald, B R, Gallagher, J A, Russell, R G

“…Despite its acute inhibitory effect on bone formation in vitro, PTH has been shown to have an anabolic effect on bone in vivo and to stimulate cell…”
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Global crop forecasting by MacDonald, R. B., Hall, F. G.

“…Many foreign countries are as dependent on imports of food as the United States is on imports of oil. As the world's largest exporter of food, the United…”
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Recombinant human transforming growth factor-alpha stimulates the formation of osteoclast-like cells in long-term human marrow cultures by TAKAHASHI, N, MACDONALD, B. R, HON, J, WINKLER, M. E, DERYNCK, R, MUNDY, G. R, ROODMAN, G. D

“…Transforming growth factor-alpha (TGF-alpha) is synthesized by a variety of tumor cell lines and stimulates osteoclastic bone resorption in vitro. The…”
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Unconventional Myosins in Inner-Ear Sensory Epithelia by Hasson, Tama, Gillespie, Peter G., Garcia, Jesus A., MacDonald, Richard B., Zhao, Yi-dong, Yee, Ann G., Mooseker, Mark S., Corey, David P.

“…To understand how cells differentially use the dozens of myosin isozymes present in each genome, we examined the distribution of four unconventional myosin…”
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Regulation of Dlx gene expression in the zebrafish pharyngeal arches: from conserved enhancer sequences to conserved activity by MacDonald, R.B, Debiais-Thibaud, M, Ekker, M

“…The Dlx genes play an important role in the development of the pharyngeal arches and the structures derived from these tissues, including the craniofacial…”
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Evaluation of LY203647 on cardiovascular leukotriene D4 receptors and myocardial reperfusion injury by Hahn, R A, MacDonald, B R, Morgan, E, Potts, B D, Parli, C J, Rinkema, L E, Whitesitt, C A, Marshall, W S

“…In vitro studies have shown LY203647 to be a selective antagonist of contractile responses to leukotriene (LT) D4 and LTE4 in guinea pig ileum, trachea and…”
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Effects of human recombinant CSF‐GM and highly purified CSF‐1 on the formation of multinucleated cells with osteoclast characteristics in long‐term bone marrow cultures by MacDonald, B. R., Mundy, G. R., Clark, S., Wang, E. A., Kuehl, T. J., Stanley, E. R., Roodman, G. D.

“…Several studies have suggested that the osteoclast is derived from a mononuclear precursor which is found in bone marrow. We have developed a system for…”
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Osteoclast-like cells form in long-term human bone marrow but not in peripheral blood cultures by TAKAHASHI, N, KUKITA, T, MACDONALD, B. R, BIRD, A, MUNDY, G. R, MCMANUS, L. M, MILLER, M, BOYDE, A, JONES, S. J, ROODMAN, G. D

“…Transplantation studies have suggested that peripheral blood mononuclear cells contain precursors for osteoclasts. Thus we tested the capacity of peripheral…”
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Antagonism of leukotriene B4 receptors does not limit canine myocardial infarct size by Hahn, R A, MacDonald, B R, Simpson, P J, Potts, B D, Parli, C J

“…Injection of leukotriene (LT)B4 (0.1-3 micrograms/kg i.v.) in normal anesthetized dogs produced dose-related leukopenia that was accompanied by arterial…”
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Proliferative responses to estradiol, IL-1α and TGFβ by cells expressing alkaline phosphatase in human osteoblast-like cell cultures by RICKARD, D. J, GOWEN, M, MACDONALD, B. R

“…The use of primary (nontransformed) bone cell cultures is hampered by their cellular heterogeneity. Primary cultures of osteoblast-like cells have been shown…”
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Primate cardiovascular responses mediated by dopamine receptors: effects of N,N-di-n-propyldopamine and LY171555 by Hahn, R A, MacDonald, B R

“…Administration of N,N-di-n-propyldopamine (DPDA) (1-100 micrograms/kg i.v.) and LY171555 (1-100 micrograms/kg i.v.) produced dose-related arterial hypotension…”
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Evaluation of activated protein C on canine infarct size in a nonthrombotic model of myocardial reperfusion injury by Hahn, R A, MacDonald, B R, Chastain, M, Grinnell, B W, Simpson, P J

“…Myocardial infarct size has been measured after 1 hr of mechanical occlusion of the circumflex coronary artery and 5 hr of reperfusion in control dogs infused…”
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Characterization of LY233569 on 5-lipoxygenase and reperfusion injury of ischemic myocardium by Hahn, R A, MacDonald, B R, Simpson, P J, Wang, L, Towner, R D, Ho, P P, Goodwin, M, Breau, A P, Suarez, T, Mihelich, E D

“…LY233569 produced concentration-dependent inhibition of isolated guinea pig 5-lipoxygenase (5-LPO) and 5-LPO activity of human polymorphonuclear leukocytes in…”
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Diamine oxidase, urticaria and intestinal oedema by MacDonald, B R, Robertson, D A

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Primate myocardial and systemic hemodynamic responses to leukotriene D4: antagonism by LY171883 by Hahn, R A, MacDonald, B R

“…Intravenous infusion of leukotriene D4 (LTD4; 0.1-10 micrograms/kg) produced dose-related depression of myocardial contractility, stroke volume index and mean…”
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Spectral characterization of biophysical characteristics in a boreal forest - Relationship between Thematic Mapper band reflectance and leaf area index for Aspen by Badhwar, G. D., Macdonald, R. B., Hall, F. G., Carnes, J. G.

“…Results from analysis of a data set of simultaneous measurements of Thematic Mapper band reflectance and leaf area index are presented. The measurements were…”
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