Search Results - "MACALA, L. J"

NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders by Estacion, M, Dib-Hajj, S. D, Benke, P. J, te Morsche, Rene H. M, Eastman, E. M, Macala, L. J, Drenth, J. P. H, Waxman, S. G

“…Gain-of-function mutations of Na(V)1.7 have been shown to produce two distinct disorders: Na(V)1.7 mutations that enhance activation produce inherited…”
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Developmental changes in ganglioside composition and synthesis in embryonic rat brain by Yu, R K, Macala, L J, Taki, T, Weinfield, H M, Yu, F S

“…Developmental changes in ganglioside composition and biosynthesis was studied in rat brain between embryonic day (E) 14 and birth. In E14 brains, GM3 and GD3…”
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Analysis of brain lipids by high performance thin-layer chromatography and densitometry by Macala, L J, Yu, R K, Ando, S

“…We have devised a high performance thin-layer chromatography (HPTLC) densitometry method to resolve the major lipid classes of brain tissue. We used…”
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Ganglioside and lipid composition of bulk-isolated rat and bovine oligodendroglia by Yu, R K, Macala, L J, Farooq, M, Sbaschnig-Agler, M, Norton, W T, Ledeen, R W

“…We have examined the ganglioside composition of 30-day and 60-day postnatal rat oligodendroglia, adult bovine oligodendroglia, gray matter, white matter, and…”
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The presence of sialidase-sensitive sialosylgangliotetraosyl ceramide (GM1b) in stimulated murine macrophages. Deficiency of GM1b in Escherichia coli-activated macrophages from the C3H/HeJ mouse by Yohe, HC, Cuny, CL, Macala, LJ, Saito, M, McMurray, WJ, Ryan, JL

“…The stimulated murine macrophage was found to contain 11 major gangliosides of which 8 were determined to be monosialylated. The thin-layer chromatographic…”
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Isolation and characterization of ganglioside 9-O-acetyl-GD3 from bovine buttermilk by Bonafede, D.M. (Yale University Medical School, New Haven, CT), Macala, L.J, Constantine-Paton, M, Yu, R.K

“…Bovine buttermilk contains a unique ganglioside, 9‐O‐acetyl‐GD3. In order to isolate large quantities of this ganglioside, a simplified isolation scheme which…”
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The G1662S NaV1.8 mutation in small fibre neuropathy: impaired inactivation underlying DRG neuron hyperexcitability by Han, Chongyang, Vasylyev, Dmytro, Macala, Lawrence J, Gerrits, Monique M, Hoeijmakers, Janneke G J, Bekelaar, Kim J, Dib-Hajj, Sulayman D, Faber, Catharina G, Merkies, Ingemar S J, Waxman, Stephen G

“…Objective Painful small fibre neuropathy (SFN) represents a significant public health problem, with no cause apparent in one-half of cases (termed idiopathic,…”
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In vitro biosynthesis of the tetrasialoganglioside GQ1b by YOHE, H. C, MACALA, L. J, YU, R. K

“…A sialyltransferase activity which catalyzes the synthesis of the tetrasialoganglioside GQ1b…”
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Measurement of cAMP-dependent protein kinase activity using a fluorescent-labeled Kemptide by Macala, Lawrence J., Hayslett, John P., Smallwood, Joan I.

“…Measurement of cAMP-dependent protein kinase activity using a fluorescent-labeled Kemptide. Traditional protein kinase assays include the use of [32P] labeled…”
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Effect of antiglycolipid antisera on the lipid composition of cultured mouse spinal cords by Saito, M, Macala, L J, Roth, G A, Bornstein, M B, Yu, R K

“…To examine the effect of antiglycolipid antibodies on demyelination, myelinated cultures of embryonic mouse spinal cords were treated by antigalactocerebroside…”
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Characterization of some minor gangliosides in Tay-Sachs brains by Yu, R K, Itoh, T, Yohe, H C, Macala, L J

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Ganglioside changes associated with temporal lobe epilepsy in the human hippocampus by Yu, R K, Holley, J A, Macala, L J, Spencer, D D

“…To understand better the molecular and cellular events associated with status epilepticus, a multifaceted analysis has begun on hippocampal tissues…”
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In situ accessibility of murine macrophage gangliosides by Macala, L J, Yohe, H C

“…Gangliosides are implicated in cell signal transduction. Prior to investigating this phenomenon in macrophages, the in situ accessibility of gangliosides to…”
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Identification and characterization of MARCKS in Xenopus laevis by Ali, N, Macala, L J, Hayslett, J P

“…MARCKS proteins are widely distributed in mammalian cells and subserve an important role as probes in the examination of signal transduction processes because…”
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Vasopressin-induced activation of protein kinase C in renal epithelial cells by Ali, Nawab, Kantachuvesiri, Surasak, Smallwood, Joan I, Macala, Lawrence J, Isales, Carlos, Ji, Jing, Reilly, Robert, Hayslett, John P

“…Recent studies indicate that the actions of arginine vasopressin (AVP) and other agonists that stimulate electrogenic sodium transport in renal epithelial A6…”
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Novel Effect of Insulin: Insulin-Stimulated Na+Transport Is Mediated by Hydrolysis of Phosphoinositides by Isales, Carlos, Macala, Lawrence J., Rodriguez-Commes, Jose, Gasalla-Herraiz, Jose, Hayslett, John P.

“…Previous studies showed that insulin stimulation of electrogenic Na+transport in renal epithelial cells is mediated by a calcium-dependent signal transduction…”
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Gangliosides of normal and neoplastic human melanocytes by Carubia, J M, Yu, R K, Macala, L J, Kirkwood, J M, Varga, J M

“…The major ganglioside component isolated from diploid human melanocytes is sialosyllactosylceramide (GM3 86-91% of total sialic acid). The corresponding…”
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Na V 1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders by Estacion, M., Dib-Hajj, S. D., Benke, P. J., te Morsche, Rene H. M., Eastman, E. M., Macala, L. J., Drenth, J. P. H., Waxman, S. G.

“…Gain-of-function mutations of Na V 1.7 have been shown to produce two distinct disorders: Na V 1.7 mutations that enhance activation produce inherited…”
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Lipid composition of PC12 pheochromocytoma cells: characterization of globoside as a major neutral glycolipid by Ariga, Toshio, Macala, Lawrence J, Saito, Megumi, Margolis, Renee K, Greene, Lloyd A, Margolis, Richard U, Yu, Robert K

“…We have studied the lipid composition of PC12 pheochromocytoma cells cultured in the presence and absence of nerve growth factor (NGF). Neutral and acidic…”
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Differential effect of D623N variant and wild-type Na(v)1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons by Ahn, Hye-Sook, Vasylyev, Dmytro V, Estacion, Mark, Macala, Lawrence J, Shah, Palak, Faber, Catharina G, Merkies, Ingemar S J, Dib-Hajj, Sulayman D, Waxman, Stephen G

“…Sodium channel NaV1.7 is preferentially expressed in dorsal root ganglion (DRG) and sympathetic ganglion neurons. Gain-of-function NaV1.7 mutations/variants…”
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