Search Results - "MAAHEIMO, H"

Mapping the Binding of Synthetic Disaccharides Representing Epitopes of Chlamydial Lipopolysaccharide to Antibodies with NMR by Maaheimo, Hannu, Kosma, Paul, Brade, Lore, Brade, Helmut, Peters, Thomas

“…A NMR study of the binding of the synthetic disaccharides α-Kdo-(2→4)-α-Kdo-(2→O)-allyl 1 (Kdo, 3-deoxy-d-manno-oct-2-ulopyranosonic acid) and…”
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The β1,6-GlcNAc transferase activity present in hog gastric mucosal microsomes catalyses site-specific branch formation on a long polylactosamine backbone by Helin, J, Penttilä, L, Leppänen, A, Maaheimo, H, Lauri, S, Costello, C.E, Renkonen, O

“…We find that the β1,6-GlcNAc transferase activity present in hog gastric mucosal microsomes converts the linear pentasaccharide…”
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Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway by Ritala, Anneli, Dong, Lemeng, Imseng, Nicole, Seppänen-Laakso, Tuulikki, Vasilev, Nikolay, van der Krol, Sander, Rischer, Heiko, Maaheimo, Hannu, Virkki, Arho, Brändli, Johanna, Schillberg, Stefan, Eibl, Regine, Bouwmeester, Harro, Oksman-Caldentey, Kirsi-Marja

“…•Tobacco hairy roots were engineered to express geraniol synthase.•A detailed metabolite analysis of transgenic hairy root cultures was performed.•Generated…”
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Human  3-fucosyltransferases convert chitin oligosaccharides to products containing a GlcNAc 1-4(Fuc 1-3)GlcNAc 1-4R determinant at the nonreducing terminus by Natunen, Jari, Aitio, Olli, Helin, Jari, Maaheimo, Hannu, Niemela, Ritva, Heikkinen, Sami, Renkonen, Ossi

“…Human [alpha]3-fucosyltransferases (Fuc-Ts) are known to convert N-acetyllactosamine to Gal[beta]1-4(Fuc[alpha]1-3)GlcNAc (Lewis x antigen); some of them…”
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Transcriptional responses of Saccharomyces cerevisiae to shift from respiratory and respirofermentative to fully fermentative metabolism by Rintala, Eija, Jouhten, Paula, Toivari, Mervi, Wiebe, Marilyn G, Maaheimo, Hannu, Penttilä, Merja, Ruohonen, Laura

“…In industrial fermentations of Saccharomyces cerevisiae, transient changes in oxygen concentration commonly occur and it is important to understand the…”
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Investigating the potential interactions between energy metabolism and recombinant protein production in Pichia pastoris by 13C-based metabolic flux analysis by Jordà, J., Jouhten, P., Maaheimo, H., Ferrer, P., Albiol, J.

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Planning optimal measurements of isotopomer distributions for estimation of metabolic fluxes by Rantanen, Ari, Mielikäinen, Taneli, Rousu, Juho, Maaheimo, Hannu, Ukkonen, Esko

“…Motivation: Flux estimation using isotopomer information of metabolites is currently the most reliable method to obtain quantitative estimates of the activity…”
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Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc by Renkonen, O, Leppänen, A, Niemelä, R, Vilkman, A, Helin, J, Penttilä, L, Maaheimo, H, Seppo, A, Suopanki, J

“…Four radiolabeled pentasaccharides, GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc, Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta…”
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Central carbon metabolism of Saccharomyces cerevisiae explored by biosynthetic fractional (13)C labeling of common amino acids by Maaheimo, H, Fiaux, J, Cakar, Z P, Bailey, J E, Sauer, U, Szyperski, T

“…Aerobic and anaerobic central metabolism of Saccharomyces cerevisiae cells was explored in batch cultures on a minimal medium containing glucose as the sole…”
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Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris by Solà, Aina, Maaheimo, Hannu, Ylönen, Katri, Ferrer, Pau, Szyperski, Thomas

“…Amino acid biosynthesis and central carbon metabolism of Pichia pastoris were studied using biosynthetically directed fractional 13C labeling. Cells were grown…”
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Complementary Acceptor and Site Specificities of Fuc-TIV and Fuc-TVII Allow Effective Biosynthesis of Sialyl-TriLex and Related Polylactosamines Present on Glycoprotein Counterreceptors of Selectins by Niemelä, R, Natunen, J, Majuri, M L, Maaheimo, H, Helin, J, Lowe, J B, Renkonen, O, Renkonen, R

“…The P-selectin counterreceptor PSGL-1 is covalently modified by mono α2,3-sialylated, multiply α1,3-fucosylated polylactosamines. These glycans are required…”
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The phosphoenolpyruvate carboxykinase also catalyzes C sub(3) carboxylation at the interface of glycolysis and the TCA cycle of Bacillus subtilis by Zamboni, N, Maaheimo, H, Szyperski, T, Hohmann, H-P, Sauer, U

“…Quantitative physiological characterization and isotopic tracer experiments revealed that pyruvate kinase mutants of Bacillus subtilis produced significantly…”
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Anatalline and other methyl jasmonate-inducible nicotine alkaloids from Nicotiana tabacum cv. By-2 cell cultures by Häkkinen, Suvi T, Rischer, Heiko, Laakso, Into, Maaheimo, Hannu, Seppänen-Laakso, Tuulikki, Oksman-Caldentey, Kirsi-Marja

“…Anatalline [2,4-di(3-pyridyl)piperidine] accumulation was shown to be induced by methyl jasmonate in Nicotiana tabacum cv. BY-2 cell cultures. Beside…”
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Cloning and functional expression of a novel GDP-6-deoxy-D-talose synthetase from Actinobacillus actinomycetemcomitans by Mäki, Minna, Järvinen, Nina, Räbinä, Jarkko, Maaheimo, Hannu, Mattila, Pirkko, Renkonen, Risto

“…Actinobacillus actinomycetemcomitans is a Gram-negative coccobacillus that can cause various forms of severe periodontitis and other nonoral infections in…”
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Human alpha3-fucosyltransferases convert chitin oligosaccharides to products containing a GlcNAcbeta1-4(Fucalpha1-3)GlcNAcbeta1-4R determinant at the nonreducing terminus by Natunen, J, Aitio, O, Helin, J, Maaheimo, H, Niemelä, R, Heikkinen, S, Renkonen, O

“…Human alpha3-fucosyltransferases (Fuc-Ts) are known to convert N-acetyllactosamine to Galbeta1-4(Fucalpha1-3)GlcNAc (Lewis x antigen); some of them transfer…”
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Synthesis of a new nanomolar saccharide inhibitor of lymphocyte adhesion: different polylactosamine backbones present multiple sialyl Lewis x determinants to L-selectin in high-affinity mode by Renkonen, Ossi, Toppila, Sanna, Penttilä, Leena, Salminen, Heidi, Helin, Jari, Maaheimo, Hannu, Costello, Catherine E., Turunen, Juha Pekka, Renkonen, Risto

“…Lymphocyte infiltration is a hallmark of acute rejections in solid organ transplants, such as cardiac allograft We have previously shown that lymphocyte…”
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Biosynthesis of branched polylactosaminoglycans. Embryonal carcinoma cells express midchain beta1,6-N-acetylglucosaminyltransferase activity that generates branches to preformed linear backbones by Leppänen, A, Zhu, Y, Maaheimo, H, Helin, J, Lehtonen, E, Renkonen, O

“…Two types of beta1,6-GlcNAc transferases (IGnT6) are involved in in vitro branching of polylactosamines: dIGnT6 (distally acting), transferring to the…”
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Enzyme-aided construction of medium-sized alditols of complete O-linked saccharides. The constructed hexasaccharide alditol Gal beta 1-4GlcNAc beta 1-6Gal beta 1-4GlcNAc beta 1-6(Gal beta 1-3)GalNAc-ol resists the action of endo-beta-galactosidase from Bacteroides fragilis by Maaheimo, H, Penttilä, L, Renkonen, O

“…We have constructed by enzyme-aided in vitro synthesis a hexasaccharide alditol Gal beta 1-4GlcNAc beta 1-6Gal beta 1-4GlcNAc beta 1-6(Gal beta 1-3) GalNAc-ol…”
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In Vitro Biosynthesis of a Decasaccharide Prototype of Multiply Branched Polylactosaminoglycan Backbones by Leppänen, Anne, Salminen, Heidi, Zhu, Ying, Maaheimo, Hannu, Helin, Jari, Costello, Catherine E, Renkonen, Ossi

“…Multiply branched polylactosaminoglycans are expressed in glycoproteins and glycolipids of many cells. Interest in their biology stems from their abundant…”
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The beta 1,6-GlcNAc transferase activity present in hog gastric mucosal microsomes catalyses site-specific branch formation on a long polylactosamine backbone by Helin, J, Penttilä, L, Leppänen, A, Maaheimo, H, Lauri, S, Costello, C E, Renkonen, O

“…We find that the beta 1,6-GlcNAc transferase activity present in hog gastric mucosal microsomes converts the linear pentasaccharide GlcNAc beta 1-3Gal beta…”
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