Search Results - "MA, Ronald C"
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Epigenomic biomarkers of cardiometabolic disease: How far are we from daily practice?
Published in Cardiovascular diabetology (07-11-2024)“…Abstract Determining whether someone has cardiometabolic disease (CMD), especially in the early stages, can be complicated. Risk stratification ordinarily…”
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Type 2 diabetes in East Asians: similarities and differences with populations in Europe and the United States
Published in Annals of the New York Academy of Sciences (01-04-2013)“…There is an epidemic of diabetes in Asia. Type 2 diabetes develops in East Asian patients at a lower mean body mass index (BMI) compared with those of European…”
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Secular trends in all-cause and cause-specific mortality rates in people with diabetes in Hong Kong, 2001–2016: a retrospective cohort study
Published in Diabetologia (01-04-2020)“…Aims/hypothesis The aim of the study was to describe trends in all-cause and cause-specific mortality rates in Hong Kong Chinese people with diabetes from 2001…”
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Diabetes and infection: review of the epidemiology, mechanisms and principles of treatment
Published in Diabetologia (01-07-2024)“…An association between diabetes and infection has been recognised for many years, with infection being an important cause of death and morbidity in people with…”
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Intergenerational diabetes and obesity-A cycle to break?
Published in PLoS medicine (31-10-2017)“…Ronald Ma and Barry Popkin discuss the urgent need and challenges to reduce intergenerational transmission of obesity and diabetes…”
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DNA methylation markers for kidney function and progression of diabetic kidney disease
Published in Nature communications (15-05-2023)“…Epigenetic markers are potential biomarkers for diabetes and related complications. Using a prospective cohort from the Hong Kong Diabetes Register, we perform…”
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Lifetime risk of developing diabetes in Chinese people with normoglycemia or prediabetes: A modeling study
Published in PLoS medicine (21-07-2022)“…Background Little is known about the lifetime risk of progression to diabetes in the Asian population. We determined remaining lifetime risk of diabetes and…”
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Diabetes in Asia and the Pacific: Implications for the Global Epidemic
Published in Diabetes care (01-03-2016)“…The last three decades have witnessed an epidemic rise in the number of people with diabetes, especially type 2 diabetes, and particularly in developing…”
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Assisted reproduction technology and long-term cardiometabolic health in the offspring
Published in PLoS medicine (07-09-2021)“…Ronald Ma and co-authors discuss Emma Norrman and colleagues' accompanying research study on the health of children born with assisted reproductive technology…”
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Do variations in insulin sensitivity and insulin secretion in pregnancy predict differences in obstetric and neonatal outcomes?
Published in Diabetologia (01-02-2021)“…Aims/hypothesis Gestational diabetes mellitus (GDM) is generally defined based on glycaemia during an OGTT, but aetiologically includes women with defects in…”
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1-year weight change after diabetes diagnosis and long-term incidence and sustainability of remission of type 2 diabetes in real-world settings in Hong Kong: An observational cohort study
Published in PLoS medicine (23-01-2024)“…Clinical trials have demonstrated that remission of type 2 diabetes can be achieved following sustained weight loss. However, the feasibility of achieving…”
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The Incidence of Adult-Onset Type 1 Diabetes: A Systematic Review From 32 Countries and Regions
Published in Diabetes care (01-04-2022)“…The epidemiology of adult-onset type 1 diabetes (T1D) incidence is not well-characterized due to the historic focus on T1D as a childhood-onset disease. We…”
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Role of maternal glucose metabolism in the association between maternal BMI and neonatal size and adiposity
Published in International Journal of Obesity (01-03-2021)“…Background/Objective One potential mechanism by which maternal obesity impacts fetal growth is through hyperglycemia below the threshold for gestational…”
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Novel lncRNA Erbb4-IR Promotes Diabetic Kidney Injury in db/db Mice by Targeting miR-29b
Published in Diabetes (New York, N.Y.) (01-04-2018)“…TGF-β/Smad signaling plays an important role in diabetic nephropathy. The present study identified a novel Smad3-dependent long non-coding RNA (lncRNA)…”
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Age-specific population attributable risk factors for all-cause and cause-specific mortality in type 2 diabetes: An analysis of a 6-year prospective cohort study of over 360,000 people in Hong Kong
Published in PLoS medicine (30-01-2023)“…The prevalence of type 2 diabetes has increased in both young and old people. We examined age-specific associations and population attributable fractions…”
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A novel electronic health record-based, machine-learning model to predict severe hypoglycemia leading to hospitalizations in older adults with diabetes: A territory-wide cohort and modeling study
Published in PLoS medicine (12-04-2024)“…Older adults with diabetes are at high risk of severe hypoglycemia (SH). Many machine-learning (ML) models predict short-term hypoglycemia are not specific for…”
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Young age at diabetes diagnosis amplifies the effect of diabetes duration on risk of chronic kidney disease: a prospective cohort study
Published in Diabetologia (01-09-2021)“…Aims/hypothesis We postulated that the increased lifetime risk of chronic kidney disease (CKD) in young-onset diabetes is attributable to both long disease…”
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Age at diagnosis, glycemic trajectories, and responses to oral glucose-lowering drugs in type 2 diabetes in Hong Kong: A population-based observational study
Published in PLoS medicine (01-09-2020)“…To address these knowledge gaps, we conducted a large register- and population-based cohort study to measure how age at diagnosis affects (1) glycemic…”
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Age- and sex-specific hospital bed-day rates in people with and without type 2 diabetes: A territory-wide population-based cohort study of 1.5 million people in Hong Kong
Published in PLoS medicine (04-08-2023)“…Type 2 diabetes affects multiple systems. We aimed to compare age- and sex-specific rates of all-cause and cause-specific hospital bed-days between people with…”
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