Search Results - "MA, B. B. Y"

Nasopharyngeal carcinoma: an evolving paradigm by Wong, Kenneth C. W., Hui, Edwin P., Lo, Kwok-Wai, Lam, Wai Kei Jacky, Johnson, David, Li, Lili, Tao, Qian, Chan, Kwan Chee Allen, To, Ka-Fai, King, Ann D., Ma, Brigette B. Y., Chan, Anthony T. C.

“…The past three decades have borne witness to many advances in the understanding of the molecular biology and treatment of nasopharyngeal carcinoma (NPC), an…”
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Convolutional neural network for discriminating nasopharyngeal carcinoma and benign hyperplasia on MRI by Wong, Lun M., King, Ann D., Ai, Qi Yong H., Lam, W. K. Jacky, Poon, Darren M. C., Ma, Brigette B. Y., Chan, K. C. Allen, Mo, Frankie K. F.

“…Objectives A convolutional neural network (CNN) was adapted to automatically detect early-stage nasopharyngeal carcinoma (NPC) and discriminate it from benign…”
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Population-based differences in treatment outcome following anticancer drug therapies by Ma, Brigette BY, FRACP, Hui, Edwin P, MRCP, Mok, Tony SK, Prof

“…Summary Population-based differences in toxicity and clinical outcome following treatment with anticancer drugs have an important effect on oncology practice…”
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The expanding universe of checkpoint inhibitors for nasopharyngeal cancer by Ma, Brigette B. Y., Hui, Edwin P., Chan, Anthony T. C.

“…Three phase 3 studies show that an immune-checkpoint inhibitor combined with chemotherapy improves progression-free survival in recurrent or metastatic…”
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Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: a genetic meta-analysis by Xing, D, Ma, X.-L, Ma, J.-X, Xu, W.-G, Wang, J, Yang, Y, Chen, Y, Ma, B.-Y, Zhu, S.-W

“…Summary Objective Knee osteoarthritis (KOA) is a common disease that is characterized by the degeneration of joint cartilage in the knee. Genetic factors have…”
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Systemic approach to improving treatment outcome in nasopharyngeal carcinoma: Current and future directions by Ma, Brigette B. Y., Hui, Edwin P., Chan, Anthony T. C.

“…Systemic therapy is an integral part of the management of non‐keratinizing nasopharyngeal carcinoma (NPC). The purposes of this review are to provide the…”
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A quartic B-spline based explicit time integration scheme for structural dynamics with controllable numerical dissipation by Wen, W. B., Duan, S. Y., Yan, J., Ma, Y. B., Wei, K., Fang, D. N.

“…An explicit time integration scheme based on quartic B-splines is presented for solving linear structural dynamics problems. The scheme is of a one-parameter…”
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Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway by Chen, Bonan, Song, Yue, Zhan, Yujuan, Zhou, Shikun, Ke, Junzi, Ao, Weizhen, Zhang, Yigan, Liang, Qiqi, He, Minhui, Li, Shuhui, Xie, Fuda, Huang, Haonan, Chan, Wai Nok, Cheung, Alvin H.K., Ma, Brigette B.Y., Kang, Wei, To, Ka Fai, Xiao, Jianyong

“…Few drugs alleviate non-small cell lung cancer (NSCLC) metastasis effectively. Small molecular screening demonstrated that fangchinoline (Fan) reversed…”
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Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing by Chan, K. C. Allen, Jiang, Peiyong, Chan, Carol W. M., Sun, Kun, Wong, John, Hui, Edwin P., Chan, Stephen L., Chan, Wing Cheong, Hui, David S. C., Ng, Simon S. M., Chan, Henry L. Y., Wong, Cesar S. C., Ma, Brigette B. Y., Chan, Anthony T. C., Lai, Paul B. S., Sun, Hao, Chiu, Rossa W. K., Lo, Y. M. Dennis

“…We explored the detection of genome-wide hypomethylation in plasma using shotgun massively parallel bisulfite sequencing as a marker for cancer…”
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Prognostic value of cervical nodal necrosis on staging imaging of nasopharyngeal carcinoma in era of intensity-modulated radiotherapy: a systematic review and meta-analysis by Ai, Qi-Yong H, Hung, Kuo Feng, So, Tiffany Y, Mo, Frankie K F, Tsung Anthony Chin, Wing, Hui, Edwin P, Ma, Brigette B Y, Ying, Michael, King, Ann D

“…To systematically review and perform meta-analysis to evaluate the prognostic value of cervical nodal necrosis (CNN) on the staging computed…”
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Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma by Lam, W. K. Jacky, Jiang, Peiyong, Chan, K. C. Allen, Cheng, Suk H., Zhang, Haiqiang, Peng, Wenlei, Tse, O. Y. Olivia, Tong, Yu K., Gai, Wanxia, Zee, Benny C. Y., Ma, Brigette B. Y., Hui, Edwin P., Chan, Anthony T. C., Woo, John K. S., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Circulating tumor-derived DNA testing for cancer screening has recently been demonstrated in a prospective study on identification of nasopharyngeal carcinoma…”
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Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079) by Ma, B. B. Y., Goh, B. C., Lim, W. T., Hui, E. P., Tan, E. H., Lopes, G. de Lima, Lo, K. W., Li, L., Loong, H., Foster, N. R., Erlichman, C., King, A. D., Kam, M. K. M., Leung, S. F., Chan, K. C., Chan, A. T. C.

“…Summary Background This study investigated the activity of MK-2206, an AKT inhibitor, in metastatic or recurrent nasopharyngeal carcinoma (NPC). Method Oral…”
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Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases by Lam, W. K. Jacky, Jiang, Peiyong, Chan, K. C. Allen, Peng, Wenlei, Shang, Huimin, Heung, Macy M. S., Cheng, Suk Hang, Zhang, Haiqiang, Tse, O. Y. Olivia, Raghupathy, Radha, Ma, Brigette B. Y., Hui, Edwin P., Chan, Anthony T. C., Woo, John K. S., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Epstein-Barr virus (EBV) is associated with a number of diseases, including malignancies. Currently, it is not known whether patients with different…”
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Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas by JIN, H, WANG, X, PUTTI, T. C, LUNG, M. L, SHEN, Z.-Y, XU, L.-Y, LANGFORD, C, TAO, Q, YING, J, WONG, A. H. Y, LI, H, LEE, K. Y, SRIVASTAVA, G, CHAN, A. T. C, YEO, W, MA, B. B. Y

“…Tumor suppressor genes (TSGs) often locate at chromosomal regions with frequent deletions in tumors. Loss of 16q23 occurs frequently in multiple tumors,…”
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Cancer‐associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2–IGF1R and Hippo–YAP1 signaling pathways by Zhang, Jinglin, Chen, Bonan, Li, Hui, Wang, Yifei, Liu, Xiaoli, Wong, Kit Yee, Chan, Wai Nok, Chan, Aden KY, Cheung, Alvin HK, Leung, Kam Tong, Dong, Yujuan, Pan, Yi, Ke, Huixing, Liang, Li, Zhou, Zhaocai, Xiao, Jianyong, Wong, Chi Chun, Wu, William KK, Cheng, Alfred SL, Ma, Brigette BY, Yu, Jun, Lo, Kwok Wai, Kang, Wei

“…Colorectal cancer (CRC) is one of the most common cancers worldwide. The tumor microenvironment exerts crucial effects in driving CRC progression…”
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Overall Survival After Concurrent Cisplatin–Radiotherapy Compared With Radiotherapy Alone in Locoregionally Advanced Nasopharyngeal Carcinoma by Chan, Anthony T. C., Leung, S. F., Ngan, Roger K. C., Teo, Peter M. L., Lau, W. H., Kwan, W. H., Hui, Edwin P., Yiu, H. Y., Yeo, Winnie, Cheung, F. Y., Yu, K. H., Chiu, K. W., Chan, D. T., Mok, Tony S. K., Yau, Stephen, Yuen, K. T., Mo, Frankie K. F., Lai, Maria M. P., Ma, Brigette B. Y., Kam, Michael K. M., Leung, Thomas W. T., Johnson, Philip J., Choi, Peter H. K., Zee, Benny C. Y.

“…This phase III randomized study compared concurrent cisplatin–radiotherapy (CRT) versus radiotherapy (RT) alone in patients with locoregionally advanced…”
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Distinguishing early-stage nasopharyngeal carcinoma from benign hyperplasia using intravoxel incoherent motion diffusion-weighted MRI by Ai, Qi-Yong, King, Ann D., Chan, Janet S. M., Chen, Weitian, Chan, K. C. Allen, Woo, John K. S., Zee, Benny C. Y., Chan, Anthony T. C., Poon, Darren M. C., Ma, Brigette B. Y., Hui, Edwin P., Ahuja, Anil T., Vlantis, Alexander C., Yuan, Jing

“…Objectives MRI can detect early-stage nasopharyngeal carcinoma (NPC), but the detection is more challenging in early-stage NPCs because they must be…”
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The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines by Ma, Brigette B. Y., Lui, Vivian W. Y., Hui, Edwin P., Lau, Cecilia P. Y., Ho, Kakiu, Ng, Margaret H. L., Cheng, S. H., Tsao, Sai-Wah, Chan, Anthony T. C.

“…Summary Phosphorylated (pi-) protein kinase B (AKT) is commonly expressed in nasopharyngeal carcinoma (NPC) cell lines and tissues, suggesting the involvement…”
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A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy by Li, Lili, Shu, Xing-sheng, Geng, Hua, Ying, Jianming, Guo, Lei, Luo, Jie, Xiang, Tingxiu, Wu, Longtao, Ma, Brigette B. Y., Chan, Anthony T. C., Zhu, Xiaofeng, Ambinder, Richard F., Tao, Qian

“…Peptides/small proteins, encoded by noncanonical open reading frames (ORF) of previously claimed non-coding RNAs, have recently been recognized possessing…”
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Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin by Sun, Kun, Jiang, Peiyong, Cheng, Suk Hang, Cheng, Timothy H T, Wong, John, Wong, Vincent W S, Ng, Simon S M, Ma, Brigette B Y, Leung, Tak Y, Chan, Stephen L, Mok, Tony S K, Lai, Paul B S, Chan, Henry L Y, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

“…Cell-free DNA (cfDNA) in human plasma is a class of biomarkers with many current and potential future diagnostic applications. Recent studies have shown that…”
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