Search Results - "M. V. Korokin"
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APPswe/PS1dE9/Blg Transgenic Mouse Line for Modeling Cerebral Amyloid Angiopathy Associated with Alzheimer's Disease
Published in Molekuliarnaia biologiia (01-01-2023)“…Alzheimer's disease (AD) is the most common proteinopathy, which is accompanied by a steady decrease in the patient's cognitive functions with a simultaneous…”
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APPswe/PS1dE9/Blg Transgenic Mouse Line for Modeling Cerebral Amyloid Angiopathy Associated with Alzheimer’s Disease
Published in Molecular biology (New York) (01-02-2023)“…Alzheimer’s disease (AD) is the most common proteinopathy, which is accompanied by a steady decrease in the patient’s cognitive functions with a simultaneous…”
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Study of Endothelial Protective Activity of Phenol-Derived Thrombin and Arginase-2 Inhibitors KUD-259 and KUD-974
Published in Bulletin of experimental biology and medicine (01-08-2017)“…We performed correction of endothelial dysfunction with phenol derivatives KUD-259 and KUD-974 containing heteroatomic and heterocyclic structures…”
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Comparative Study of Potential Endothelioprotectors and Impaza in Modeled Nitric Oxide Defi ciency
Published in Bulletin of experimental biology and medicine (01-09-2009)“…Experimental NO deficiency induced by L-NAME injection led to the development of arterial hypertension, endothelial dysfunction, and cardiomyocyte hypertrophy…”
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Study of the anti-inflammatory and immunotropic activity of the secretome from multipotent mesenchymal stromal cells induced by erythropoietin, valproic acid or dexamethasone in vitro
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (14-04-2022)“…The aim of this study was to evaluate the effect of treatment with valproic acid, erythropoietin, and dexamethasone on the anti-inflammatory and…”
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CONVENTIONAL APPROACHES TO THE THERAPY OF HEREDITARY MYOPATHIES
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (01-01-2022)“…The aim of the work was to analyze the available therapeutic options for the conventional therapy of hereditary myopathies. Materials and methods. When…”
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Protective role of 3-oxypyridine derivatives in rats’ steroid-induced osteoporosis associated with reduced oxidative stress and recovery of nitric oxide formation
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (01-01-2023)“…From the point of view of the mechanisms for the implementation of pathogenetic links in the development of steroid-induced osteoporosis considered in the…”
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В6.А-DYSFPRMD/GENEJ MICE AS A GENETIC MODEL OF DYSFERLINOPATHY
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (16-12-2022)“…The aim of the work was behavioral and pathomorphological phenotyping of the mice knockout for the DYSF gene, which plays an important role in the development…”
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Increased Expression of the Multimerin-1 Gene in α-Synuclein Knokout Mice
Published in Doklady. Biological sciences (01-09-2020)“…Multimerin-1 (Mmrn-1) is a soluble protein, also known as elastin microfibril interfacer 4 (EMILIN-4), found in platelets and in the endothelium of blood…”
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11-amino acid peptide imitating the structure of erythropoietin α-helix b improves endothelial function, but stimulates thrombosis in rats
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (2019)“…The aim of the study was to test whether P-αB can be positioned as a preventing and treating agent for cardiovascular diseases. Materials and methods. The…”
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DEVELOPMENT OF MURINE STEM CELLS WITH CONDITIONAL KNOCKOUT OF HUMANIZED SNCA GENE
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (01-01-2022)“…α-synuclein is one of the key molecular links in the pathogenesis of Parkinson’s disease. The accumulated data indicate that pathogenic mutations in the Snca…”
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APPLICATION OF MULTIPOTENT MESENCHYMAL STEM CELL SECRETOME IN THE TREATMENT OF ADJUVANT ARTHRITIS AND CONTACT-ALLERGIC DERMATITIS IN ANIMAL MODELS
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (01-01-2020)“…The therapeutic effect of multipotent mesenchymal stem cells has been proven on various disease models. One of the mechanisms is the paracrine effect of the…”
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Effect of L-arginine, vitamin B6 and folic acid on parameters of endothelial dysfunction and microcirculation in the placenta in modeling of L-NAME-induced NO deficiency
Published in Bulletin of experimental biology and medicine (01-11-2011)“…L-arginine (200 mg/kg), vitamin B(6) (2 mg/kg), and folic acid (0.2 mg/kg) exert a protective effect on endothelial function in L-NAME-induced NO deficiency in…”
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A Model of Hyperhomocysteine-Induced Endothelial Dysfunction in Rats
Published in Bulletin of experimental biology and medicine (01-12-2011)“…Intragastric methionine (3 g/kg daily for 7 days) elevates homocysteine concentration and increases the endothelial dysfunction coefficient. This protocol of…”
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Comparative study of potential endothelioprotectors and impaza in modeled nitric oxide deficiency
Published in Bulletin of experimental biology and medicine (01-09-2009)“…Experimental NO deficiency induced by L-NAME injection led to the development of arterial hypertension, endothelial dysfunction, and cardiomyocyte hypertrophy…”
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PHARMACOLOGICAL CORRECTION OF THE PURULENT PROCESS OF WOUND BY PHYTOMINERALSORBENTUM IN RATS
Published in Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik (01-06-2017)“…Sorbtions and biological active compounds are perspective drugs for treatment of the purulent wounds. Results of the wound healing with phytomineralsorbent are…”
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REALITIES AND PROSPECTS FOR PHARMACOLOGICAL CORRECTION OF «ADMA-ENOS"-ASSOCIATED WAYS IN PREECLAMPSIA
Published in Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii (01-01-2010)“…Methylated analogs of L-arginine - asymmetric dimetilarginin (ADMA) and monometilarginin (L-NMMA) - are endogenous inhibitors of endothelial NO-synthase…”
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EFFECT OF FUROSTANOL GLYCOSIDES FROM CULTURED DIOSCOREA DELTOIDEA CELLS ON REGULATORY FUNCTION OF ENDOTHELIUM IN A RAT MODEL OF HYPOESTROGEN-INDUCED ENDOTHELIAL DYSFUNCTION
Published in Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii (01-01-2008)“…Aim. To study the effects of furostanol glycosides from cultured Dioscorea Deltoidea cells (DM-05, Institute of Plant Physiology, RAS) on physiological and…”
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Effect of L-Arginine, Vitamin B6 and Folic Acid on Parameters of Endothelial Dysfunction and Microcirculation in the Placenta in Modelinhg of L-NAME-Induced NO Deficiency
Published in Bulletin of experimental biology and medicine (01-11-2011)“…L-arginine (200 mg/kg), vitamin B 6 (2 mg/kg), and folic acid (0.2 mg/kg) exert a protective effect on endothelial function in L-NAME-induced NO defi ciency in…”
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Effect of L-Arginine, Vitamin B^sub 6^ and Folic Acid on Parameters of Endothelial Dysfunction and Microcirculation in the Placenta in Modelinhg of L-NAME-Induced NO Deficiency
Published in Bulletin of experimental biology and medicine (01-10-2011)“…Issue Title: This issue is a translation of Byulleten' Eksperimental'noi Biologii i Meditsiny (Bulletin of Experimental Biology and Medicine) and Kletochnye…”
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