Search Results - "M. Silva, Raquel"

Gains, losses and changes of function after gene duplication: study of the metallothionein family by Moleirinho, Ana, Carneiro, João, Matthiesen, Rune, Silva, Raquel M, Amorim, António, Azevedo, Luísa

“…Metallothioneins (MT) are small proteins involved in heavy metal detoxification and protection against oxidative stress and cancer. The mammalian MT family…”
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Population wide testing pooling strategy for SARS-CoV-2 detection using saliva by Esteves, Eduardo, Mendes, Ana Karina, Barros, Marlene, Figueiredo, Cátia, Andrade, Joana, Capelo, Joana, Novais, António, Rebelo, Carla, Soares, Rita, Nunes, Ana, Ferreira, André, Lemos, Joana, Duarte, Ana Sofia, Silva, Raquel M, Inácio Bernardino, Liliana, Correia, Maria José, Esteves, Ana Cristina, Rosa, Nuno

“…SARS-CoV-2 pandemic has forced frequent testing of populations. It is necessary to identify the most cost-effective strategies for the detection of COVID-19…”
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Essential genetic findings in neurodevelopmental disorders by Cardoso, Ana R, Lopes-Marques, Mónica, Silva, Raquel M, Serrano, Catarina, Amorim, António, Prata, Maria J, Azevedo, Luísa

“…Neurodevelopmental disorders (NDDs) represent a growing medical challenge in modern societies. Ever-increasing sophisticated diagnostic tools have been…”
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Three minimal sequences found in Ebola virus genomes and absent from human DNA by Silva, Raquel M, Pratas, Diogo, Castro, Luísa, Pinho, Armando J, Ferreira, Paulo J S G

“…Ebola virus causes high mortality hemorrhagic fevers, with more than 25 000 cases and 10 000 deaths in the current outbreak. Only experimental therapies are…”
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Exosomal Aβ-Binding Proteins Identified by "In Silico" Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease by Soares Martins, Tânia, Marçalo, Rui, Ferreira, Maria, Vaz, Margarida, Silva, Raquel M, Martins Rosa, Ilka, Vogelgsang, Jonathan, Wiltfang, Jens, da Cruz E Silva, Odete A B, Henriques, Ana Gabriela

“…The potential of exosomes as biomarker resources for diagnostics and even for therapeutics has intensified research in the field, including in the context of…”
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Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors by Duarte-Pereira, Sara, Pereira-Castro, Isabel, Silva, Sarah S, Correia, Mariana Gonçalves, Neto, Célia, da Costa, Luís Teixeira, Amorim, António, Silva, Raquel M

“…Nicotinamide adenine dinucleotide (NAD) is a cofactor in redox reactions and a substrate for NAD-consuming enzymes, such as PARPs and sirtuins. As cancer cells…”
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Study of NAD-interacting proteins highlights the extent of NAD regulatory roles in the cell and its potential as a therapeutic target by Duarte-Pereira, Sara, Matos, Sérgio, Oliveira, José Luís, Silva, Raquel M.

“…Nicotinamide adenine dinucleotide (NAD) levels are essential for the normal physiology of the cell and are strictly regulated to prevent pathological…”
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Merging microarray studies to identify a common gene expression signature to several structural heart diseases by Fajarda, Olga, Duarte-Pereira, Sara, Silva, Raquel M, Oliveira, José Luís

“…Heart disease is the leading cause of death worldwide. Knowing a gene expression signature in heart disease can lead to the development of more efficient…”
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Molecular Techniques and Target Selection for the Identification of Candida spp. in Oral Samples by Magalhães, Joana, Correia, Maria José, Silva, Raquel M., Esteves, Ana Cristina, Alves, Artur, Duarte, Ana Sofia

“…Candida species are the causative agent of oral candidiasis, with medical devices being platforms for yeast anchoring and tissue colonization. Identifying the…”
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The transcription factor Ndt80 is a repressor of Candida parapsilosis virulence attributes by Branco, Joana, Martins-Cruz, Cláudia, Rodrigues, Lisa, Silva, Raquel M., Araújo-Gomes, Nuno, Gonçalves, Teresa, Miranda, Isabel M., Rodrigues, Acácio G.

“…Candida parapsilosis is an emergent opportunistic yeast among hospital settings that affects mainly neonates and immunocompromised patients. Its most…”
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Evolution of the NET (NocA, Nlz, Elbow, TLP-1) protein family in metazoans: insights from expression data and phylogenetic analysis by Pereira, Filipe, Duarte-Pereira, Sara, Silva, Raquel M., da Costa, Luís Teixeira, Pereira-Castro, Isabel

“…The NET (for NocA, Nlz, Elbow, TLP-1) protein family is a group of conserved zinc finger proteins linked to embryonic development and recently associated with…”
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Comparison of Compression-Based Measures with Application to the Evolution of Primate Genomes by Pratas, Diogo, Silva, Raquel M, Pinho, Armando J

“…An efficient DNA compressor furnishes an approximation to measure and compare information quantities present in, between and across DNA sequences, regardless…”
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DNA word analysis based on the distribution of the distances between symmetric words by Tavares, Ana H. M. P., Pinho, Armando J., Silva, Raquel M., Rodrigues, João M. O. S., Bastos, Carlos A. C., Ferreira, Paulo J. S. G., Afreixo, Vera

“…We address the problem of discovering pairs of symmetric genomic words (i.e., words and the corresponding reversed complements) occurring at distances that are…”
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Metagenomic Composition Analysis of an Ancient Sequenced Polar Bear Jawbone from Svalbard by Pratas, Diogo, Hosseini, Morteza, Grilo, Gonçalo, Pinho, Armando J, Silva, Raquel M, Caetano, Tânia, Carneiro, João, Pereira, Filipe

“…The sequencing of ancient DNA samples provides a novel way to find, characterize, and distinguish exogenous genomes of endogenous targets. After sequencing,…”
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Molecular mechanisms of ischemia and glutamate excitotoxicity by Neves, Diogo, Salazar, Ivan L., Almeida, Ramiro D., Silva, Raquel M.

“…Excitotoxicity is classically defined as the neuronal damage caused by the excessive release of glutamate, and subsequent activation of excitatory plasma…”
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Fatigue related to radiotherapy for breast and/or gynaecological cancer: a systematic review by de M Alcântara-Silva, Tereza Raquel, Freitas-Junior, Ruffo, Freitas, Nilceana MA, Machado, Graziela DP

“…Aims and objectives To assess the profile, evaluation criteria and fatigue treatment. Background Fatigue, characterised by tiredness, weakness or lack of…”
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The role of recombination in the origin and evolution of Alu subfamilies by Teixeira-Silva, Ana, Silva, Raquel M, Carneiro, João, Amorim, António, Azevedo, Luísa

“…Alus are the most abundant and successful short interspersed nuclear elements found in primate genomes. In humans, they represent about 10% of the genome,…”
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FKS2 Mutations Associated with Decreased Echinocandin Susceptibility of Candida glabrata following Anidulafungin Therapy by COSTA-DE-OLIVEIRA, Sofia, MARCOS MIRANDA, Isabel, SILVA, Raquel M, E SILVA, Ana Pinto, ROCHA, Rita, AMORIM, António, GONGALVES RODRIGUES, Acácio, PINA-VAZ, Cidália

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The evolutionary portrait of metazoan NAD salvage by Carneiro, João, Duarte-Pereira, Sara, Azevedo, Luísa, Castro, L Filipe C, Aguiar, Paulo, Moreira, Irina S, Amorim, António, Silva, Raquel M

“…Nicotinamide Adenine Dinucleotide (NAD) levels are essential for cellular homeostasis and survival. Main sources of intracellular NAD are the salvage pathways…”
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Proteostasis networks in aging: novel insights from text-mining approaches by Neves, Diogo, Duarte-Pereira, Sara, Matos, Sérgio, Silva, Raquel M.

“…Aging is a topic of paramount importance in an increasingly elderly society and has been the focus of extensive research. Protein homeostasis (proteostasis)…”
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