Search Results - "M. S. Ferreira, Jaqueline"
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Identification of Zika Virus NS2B-NS3 Protease Inhibitors by Structure-Based Virtual Screening and Drug Repurposing Approaches
Published in Journal of chemical information and modeling (24-02-2020)“…The NS2B-NS3 protease has been identified as an attractive target for drug development against Zika virus (ZIKV) and combined drug repurposing and…”
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Identification of a Potential Zika Virus Inhibitor Targeting NS5 Methyltransferase Using Virtual Screening and Molecular Dynamics Simulations
Published in Journal of chemical information and modeling (24-02-2020)“…The NS5 methyltransferase (MTase) has been reported as an attractive molecular target for antivirals discovery against the Zika virus (ZIKV). Here, we report…”
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Synthesis and Evaluation of the in vitro Antimicrobial Activity of Triazoles, Morpholines and Thiosemicarbazones
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-01-2019)“…Microbial infections is a global public health problem. The aim of this work was to synthesize and evaluate the antimicrobial activity of novel triazoles,…”
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Anti-Mayaro virus activity of a hydroethanolic extract from Fridericia chica (Bonpl.) L. G. Lohmann leaves
Published in Journal of ethnopharmacology (05-12-2022)“…ETHNOPHARMACOLOGICAL RELEVANCEMayaro fever is a neglected tropical disease. The region of the most significant circulation of the Mayaro virus (MAYV) is the…”
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A 3-alkylpyridine-bearing alkaloid exhibits potent antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) with no detectable resistance
Published in Microbiological research (01-08-2022)“…Staphylococcus aureus is a Gram-positive bacterium responsible for a wide variety of infectious diseases, and its methicillin-resistant isolates pose a serious…”
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Design, synthesis, biological activity and structure-activity relationship studies of chalcone derivatives as potential anti-Candida agents
Published in Journal of antibiotics (01-08-2018)“…Vulvovaginal candidiasis (VVC) affects millions of women around the world every year. Candida albicans is the most frequently isolated pathogen in women and…”
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Antifungal activity of a novel 3-Alkylpyridine analog derived from Marine sponge alkaloids
Published in Anais da Academia Brasileira de Ciências (01-01-2021)“…Abstract Candida spp. is considered an important cause of healthcare-associated infections worldwide. Currently, the emergence and spread of resistant Candida…”
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NEW Cu (II), Co (II) AND Sn (II) COMPLEXES WITH THE SODIUM HYDROTRIS(2-MERCAPTOTHIAZOLYL)BORATE LIGAND
Published in Química Nova (01-05-2020)“…The emergence of antibiotic resistance among microbial pathogens is a serious public health problem, resulting in a constant need of discovering new…”
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Antibacterial activity of Lamiaceae plant extracts in clinical isolates of multidrug-resistant bacteria
Published in Anais da Academia Brasileira de Ciências (01-04-2018)“…The antibacterial activity of plant extracts of the Lamiaceae family was evaluated against clinical isolates of multi-resistant Gram-negative bacteria by broth…”
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Volatile compounds of Lamiaceae exhibit a synergistic antibacterial activity with streptomycin
Published in Brazilian journal of microbiology (2014)“…Bacterial infections cause thousands of deaths in the world every year. In most cases, infections are more serious because the patient is already weakened, and…”
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Antifungal Activity Directed Toward the Cell Wall by 2-Cyclohexylidenhydrazo- 4-Phenyl-Thiazole Against Candida albicans
Published in Infectious disorders drug targets (2019)“…The increasing incidence of invasive forms of candidiasis and resistance to antifungal therapy leads us to seek new and more effective antifungal compounds. To…”
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Combination of extracts from Aristolochia cymbifera with streptomycin as a potential antibacterial drug
Published in SpringerPlus (03-09-2013)“…The appearance of new antibiotic-resistant bacteria is a societal problem that requires the development of new alternative treatments. Therefore, this work…”
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Synthesis, in vitro Antifungal Activity and Molecular Modeling Studies of New Mannich Bases Derived from Lawsone
Published in Journal of the Brazilian Chemical Society (01-11-2016)“…Hydroxynaphthoquinones such as lawsone (2-hydroxy-1,4-naphthoquinone) have proven to be effective antifungal agents. These compounds were tested for antifungal…”
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Antibacterial and antibiofilm activities of synthetic analogs of 3-alkylpyridine marine alkaloids
Published in Medicinal chemistry research (01-06-2020)“…Nowadays, the emergence of superbugs is one of the most serious public health problems. Strains of Staphylococcus aureus and Klebsiella pneumoniae , resistant…”
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Synthesis, characterization and antimicrobial activity of Cr (III), Co (II) and Ni (II) complexes with 2-thiazoline-2-tiol derivative ligands against bacteria and yeasts of clinical importance
Published in Anais da Academia Brasileira de Ciências (01-01-2019)“…Four novel Cr (III), Co (II) and Ni (II) complexes with 2-thiazoline-2-tiol derivative ligands were synthesized and characterized using elemental,…”
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Passatempo virus, a vaccinia virus strain, Brazil
Published in Emerging infectious diseases (01-12-2005)“…Passatempo virus was isolated during a zoonotic outbreak. Biologic features and molecular characterization of hemagglutinin, thymidine kinase, and vaccinia…”
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