Search Results - "M. Pawlicki"

Tissue-Specific Mitotic Bookmarking by Hematopoietic Transcription Factor GATA1 by Kadauke, Stephan, Udugama, Maheshi I., Pawlicki, Jan M., Achtman, Jordan C., Jain, Deepti P., Cheng, Yong, Hardison, Ross C., Blobel, Gerd A.

“…Tissue-specific transcription patterns are preserved throughout cell divisions to maintain lineage fidelity. We investigated whether transcription factor GATA1…”
Get full text

Primary microRNA Transcript Retention at Sites of Transcription Leads to Enhanced microRNA Production by Pawlicki, Jan M., Steitz, Joan A.

“…MicroRNAs (miRNAs) are noncoding RNAs with important roles in regulating gene expression. In studying the earliest nuclear steps of miRNA biogenesis, we…”
Get full text

Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function by Pawlicki, Jan M, Steitz, Joan A

“…The expression of protein-coding genes is enhanced by the exquisite coupling of transcription by RNA polymerase II with pre-messenger RNA processing reactions,…”
Get full text

Cold upset forging joining of ultra-fine-grained aluminium and copper by Pawlicki, M., Drenger, T., Pieszak, M., Borowski, J.

“…This paper describes a study investigating joining copper, which is expensive but has excellent electrical properties, with aluminium, which is cheaper but is…”
Get full text

Zoledronic Acid Versus Placebo in the Treatment of Skeletal Metastases in Patients With Lung Cancer and Other Solid Tumors: A Phase III, Double-Blind, Randomized Trial—The Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group by ROSEN, Lee S, GORDON, David, REITSMA, Dirk, SEAMAN, John J, TCHEKMEDYIAN, Simon, YANAGIHARA, Ronald, HIRSH, Vera, KRZAKOWSKI, M, PAWLICKI, M, DE SOUZA, Paul, MING ZHENG, URBANOWITZ, Gladys

“…To assess the efficacy and safety of zoledronic acid in patients with bone metastases secondary to solid tumors other than breast or prostate cancer. Patients…”
Get full text

Subnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: Processing at transcription sites or accumulation in SC35 foci by Pawlicki, Jan M., Steitz, Joan A.

“…MicroRNAs (miRNAs) are small, noncoding RNAs that posttranscriptionally regulate expression of their target messenger RNAs. We recently demonstrated that…”
Get full text

Mechanical and Structural Behavior of Copper Subjected to the Flow Forming Process by Pawlicki, M., Bochniak, W.

“…This work paper presents the results of HV 0.5 microhardness measurements and structural documentation of copper before and after the concurrent elongating…”
Get full text

SRL172 (killed Mycobacterium vaccae) in addition to standard chemotherapy improves quality of life without affecting survival, in patients with advanced non-small-cell lung cancer: phase III results by O’Brien, M. E. R., Anderson, H., Kaukel, E., O’Byrne, K., Pawlicki, M., von Pawel, J., Reck, M.

“…Background: This open-label, randomised phase III study was designed to further investigate the clinical activity and safety of SRL172 (killed Mycobacterium…”
Get full text

The effect of molluscan glue proteins on gel mechanics by Pawlicki, J M, Pease, L B, Pierce, C M, Startz, T P, Zhang, Y, Smith, A M

“…Several molluscs have been shown to alternate between a non-adhesive trail mucus and a similar gel that forms a strong glue. The major structural difference…”
Get full text

Vinorelbine plus trastuzumab combination as first-line therapy for HER 2-positive metastatic breast cancer patients: an international phase II trial by CHAN, A, MARTIN, M, PAWLICKI, M, AUBERT, D, BOURLARD, T, GASMI, J, VILLANOVA, G, PETRUZELKA, L, UNTCH, M, GIL, M. G, GUILLEM-PORTA, V, WOJTUKIEWICZ, M, KELLOKUMPU-LEHTINEN, P, SOMMER, H. L, GEORGOULIAS, V, BATTELLI, N

“…The aim of this international phase II trial was to determine the efficacy and safety profile of weekly vinorelbine plus trastuzumab as first-line chemotherapy…”
Get full text

NPM-ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation by Pawlicki, Jan M, Cookmeyer, David L, Maseda, Damian, Everett, John K, Wei, Fang, Kong, Hong, Zhang, Qian, Wang, Hong Y, Tobias, John W, Walter, David M, Zullo, Kelly M, Javaid, Sarah, Watkins, Amanda, Wasik, Mariusz A, Bushman, Frederic D, Riley, James L

“…Fusion genes including NPM-ALK can promote T-cell transformation, but the signals required to drive a healthy T cell to become malignant remain undefined. In…”
Get full text

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality by Saha, Asim, O'Connor, Roddy S, Thangavelu, Govindarajan, Lovitch, Scott B, Dandamudi, Durga Bhavani, Wilson, Caleph B, Vincent, Benjamin G, Tkachev, Victor, Pawlicki, Jan M, Furlan, Scott N, Kean, Leslie S, Aoyama, Kazutoshi, Taylor, Patricia A, Panoskaltsis-Mortari, Angela, Foncea, Rocio, Ranganathan, Parvathi, Devine, Steven M, Burrill, Joel S, Guo, Lili, Sacristan, Catarina, Snyder, Nathaniel W, Blair, Ian A, Milone, Michael C, Dustin, Michael L, Riley, James L, Bernlohr, David A, Murphy, William J, Fife, Brian T, Munn, David H, Miller, Jeffrey S, Serody, Jonathan S, Freeman, Gordon J, Sharpe, Arlene H, Turka, Laurence A, Blazar, Bruce R

“…Programmed death ligand-1 (PD-L1) interaction with PD-1 induces T cell exhaustion and is a therapeutic target to enhance immune responses against cancer and…”
Get full text

Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection by Jacobson, Jeffrey M, Zahrieh, David, Strand, Carrie A, Cruz-Correa, Marcia, Pungpapong, Surakit, Roberts, Lewis R, Mandrekar, Sumithra J, Rodriguez, Luz Maria, Boyer, Jean, Marrero, Idania, Kraynyak, Kimberly A, Morrow, Matthew P, Sylvester, Albert J, Pawlicki, Jan M, Gillespie, Elisabeth, Barranco, Eduardo, Richmond, Ellen, Umar, Asad, Weiner, David B, Limburg, Paul J

“…Chronic hepatitis C can lead to cirrhosis and hepatocellular carcinoma. We studied the safety and immunogenicity of a novel therapeutic hepatitis C virus (HCV)…”
Get full text

Treatment for primary refractory Hodgkin's disease: a comparison of high-dose chemotherapy followed by ASCT with conventional therapy by CZYZ, J, SZYDLO, R, AVIGDOR, A, NAGLER, A, ZEMELKA, T, PAWLICKI, M, SAWICKI, Z, WOJTUKIEWICZ, M, KACHEL, L, HOLOWIECKI, J, CHARLINSKI, G, JEDRZEJCZAK, W. W, KNOPINSKA-POSLUSZNY, W, HELLMANN, A, GOZDZIK, J, HANSZ, J, SMOLEWSKI, P, ROBAK, T, OSOWIECKI, M, WALEWSKI, J

“…Our previously published study showed promising results of autologous stem cell transplantation (ASCT) in patients with primary resistant Hodgkin's disease…”
Get full text

Comparison of toremifene and tamoxifen in post-menopausal patients with advanced breast cancer: a randomized double-blind, the 'nordic' phase III study by PYRHÖNEN, S, VALAVAARA, R, MELLA, O, NILSSON, I, HIETANEN, T, HINDY, I, VUORINEN, J, HAJBA, A, MODIG, H, PAWLICKI, M, PIENKOWSKI, T, GUNDERSEN, S, BAUER, J, WESTMAN, G, LUNDGREN, S, BLANCO, G

“…The study was planned to compare, in a prospective double-blind randomized trial, the efficacy and safety of toremifene (TOR) and tamoxifen (TAM) in…”
Get full text

A Phase II Study of Intravenous Navelbine and Doxorubicin Combination in Previously Untreated Advanced Breast Carcinoma by Pawlicki, M., Rolski, J., Zaluski, J., Siedlecki, P., Ramlau, C., Tomzak, P.

“…Purpose. The combination of vinorelbine and doxorubicin, two very active drugs in metastatic breast cancer, has demonstrated impressive results in terms of…”
Get full text

The Rosai-Dorfman Syndrome in a 17-year-old woman with transformation into high-grade lymphoma. A rare case presentation by Krzemieniecki, K., Pawlicki, M., Margasska, K., Parczewska, J.

Get full text

Oxatriphyrins(2.1.1) Incorporating an ortho-Phenylene Motif by Pawlicki, Miłosz, Garbicz, Mateusz, Szterenberg, Ludmiła, Latos-Grażyński, Lechosław

“…An understanding of fundamental aspects of archetypal organic structural motifs remains a key issue faced by the experimental and theoretical chemists. Two…”
Get full text

Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: A randomized, phase III, double-blind, placebo-controlled trial by ROSEN, Lee S, GORDON, David, REITSMA, Dirk, SEAMAN, John, TCHEKMEDYIAN, N. Simon, YANAGIHARA, Ronald, HIRSH, Vera, KRZAKOWSKI, Maciej, PAWLICKI, Marek, DE SOUZA, Paul, MING ZHENG, URBANOWITZ, Gladys

“…The authors previously reported the efficacy of a dose of 4 mg of zoledronic acid in reducing skeletal complications in patients with bone metastases secondary…”
Get full text

Maintaining Normal Hemoglobin Levels With Epoetin Alfa in Mainly Nonanemic Patients With Metastatic Breast Cancer Receiving First-Line Chemotherapy: A Survival Study by LEYLAND-JONES, Brian, SEMIGLAZOV, Vladimir, BIAKHOV, Mikhail, VALUCKAS, Konstantinas, VOZNYI, Edouard, XIANGYANG LIU, VERCAMMEN, Els, PAWLICKI, Marek, PIENKOWSKI, Tadeusz, TJULANDIN, Sergei, MANIKHAS, George, MAKHSON, Antoly, ROTH, Anton, DODWELL, David, BASELGA, Jose

“…To evaluate the effect on survival and quality of life of maintaining hemoglobin (Hb) in the range of 12 to 14 g/dL with epoetin alfa versus placebo in women…”
Get full text