Search Results - "M. N. Zakharova"

Monoclonal Antibodies in Neurology: Current State and Future Development by Zakharova, M. N.

“…Monoclonal antibodies are one of the fastest growing areas of specific therapy for cancer, infectious, autoimmune, and demyelinating diseases. The main targets…”
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Mechanisms of Neurodegeneration in Multiple Sclerosis by Eliseeva, D. D., Zakharova, M. N.

“…Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), which leads to the formation of foci of primary demyelination in…”
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Adaptive Modification of Amino Acid Pools in the Myocardium of a Long-Tailed Ground Squirrel Urocitellus undulatus at Different Stages of Hibernation by Karanova, M. V., Zakharova, N. M.

“…The state of hibernation is characterized by an increased tolerance to long-term deep hypothermia, hypoxia, lack of food and water. At the same time, even a…”
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A Comparative Study of the Temperature Coefficient Q10 in Hibernating Ground Squirrels Urocitellus undulatus and Cooled Rats of Different Ages by Zakharova, N. M., Tarahovsky, Yu. S., Khrenov, M. O.

“…The temperature coefficients of heart rate ( Q10 HR ) or oxygen consumption ( Q10 Ox ) were analyzed upon arousal from natural hibernation in long-tailed…”
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The Development of Various Speech Components and Their Relations with the State of the Brain Executive Functions in Senior Preschool Age by Zakharova, M. N., Agris, A. R.

“…The brain executive functions (EFs) are crucial for various aspects of child development, as they stipulate control of cognitive processes and behavior. Speech…”
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Activities of Succinate Dehydrogenase and Lactate Dehydrogenase in Blood Lymphocytes in Yakut Ground Squirrels Spermophilus undulatus During Hibernation and in the Active State by Khunderyakova, N. V., Zakharova, N. M.

“…We studied energy metabolism in blood lymphocytes of Yakut ground squirrels Spermophilus undulatus in active state and during hibernation. Activities of…”
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The Effectiveness of Detecting Thematic Relations of Objects in 3–6 Year Old Children by Kurganskii, A. V., Zakharova, M. N., Kayumov, D. D., Antonova, S. Yu

“…In this study, the ability of preschoolers aged 3–6 to detect and understand the thematic connections of objects was assessed. Children (95 children; 53 girls…”
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Provision of alemtuzumab safety is one of the main components of pharmacovigilance by Khachanova, N V, Bakhtiyarova, K Z, Boyko, A N, Vlasov, Ya V, Davydovskaia, M V, Evdoshenko, E P, Zakharova, M N, Malkova, N A, Sivertseva, S A, Spirin, N N, Stolyarov, I D, Schmidt, T E, Khabirov, F A

“…Modern multiple sclerosis therapy with disease-modifying drugs is characterized by the risks of dangerous infectious complications. In the last 5 years, there…”
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The Level of Anti-Viral Antigen-Specific Antibodies to EBNA-1 in the Serum of MS Patients Does not Depend on the Severity of the Disease by Ovchinnikova, L. A., Dzhelad, S. S., Simaniv, T. O., Zakharova, M. N., Gabibov, A. G., Lomakin, Y. A.

“…Multiple sclerosis (MS) is an autoimmune neurodegenerative disease leading to inevitable disability and primarily affecting the young and middle-aged…”
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Adaptive Blood Cell Variability in the Annual Life Cycle of the Ground Squirrel Urocitellus undulatus by Teplova, P. O., Komelina, N. P., Yegorov, A. Ye, Lizorkina, K. I., Zakharova, N. M.

“…The complete blood count (CBC) dynamics was investigated in long-tailed ground squirrels Urocitellus undulatus ( n = 100) during different periods of their…”
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Exploring the Split-Hand Phenomenon in ALS with Motor unit Number Index (MUNIX) by Abramova, A. A., Broutian, A. G., Zakharova, M. N.

“…Split-hand phenomenon in amyotrophic lateral sclerosis (ALS) is characterized by uneven progression of muscle weakness in the intrinsic hand muscles, with…”
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Effect of Cooling on Force-Frequency Relationship, Rest Potentiation, and Frequency-Dependent Acceleration of Relaxation in the Guinea Pig Myocardium by Averin, A. S., Zakharova, N. M., Tarlachkov, S. V.

“…While deep hypothermia is well known to lead to cardiac malfunction up to circulatory arrest, mild hypothermia can prevent hypoxic damage to the heart…”
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Development of a Panel of Biomarkers for Differential Diagnosis of Multiple Sclerosis by Ovchinnikova, L. A., Dzhelad, S. S., Simaniv, T. O., Zakharova, M. N., Lomakin, Y. A., Gabibov, A. G., Illarioshkin, S. N.

“…Abstract— Demyelinating diseases are a group of heterogeneous pathologies that affect the nervous system and reduce the quality of life. One of such diseases…”
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The effectiveness of the use of Energia-M growth regulator in the protection system of winter wheat by Artemieva, E. A., Zakharova, M. N., Rozhkova, L. V.

“…In the formation of the winter wheat yield, the protection of the crop from pests, stress, pesticides and adverse abiotic factors is one of the important…”
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Motor Unit Number Index (MUNIX): A Biomarker for Evaluation of Lower Motor Neuron Involvement in Amyotrophic Lateral Sclerosis by Abramova, Anna A., Broutian, Amayak G., Zakharova, M. N.

“…Although multiple clinical trials of various therapeutic interventions in amyotrophic lateral sclerosis (ALS) have been conducted so far, most of them lack…”
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The infectious status of patients with optic neuritis of inflammatory and demyelinating etiologies by Neroev, V. V., Eliseeva, E. K., Krichevskaya, G. I., Davydova, G. A., Zakharova, M. N.

“…Purpose : to study the prevalence of various chronic infections, the frequency of their reactivation and characteristic associations of microorganisms in…”
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The place of virtual reality in the rehabilitation of patients with multiple sclerosis by Korzhova, Iu. E., Fuks, A. A., Klochkov, A. S., Khizhnikova, A. E., Suponeva, N. A., Zakharova, M. N.

“…Multiple sclerosis (MS) is a chronic autoimmune disease that limits the ability to work and lead an active lifestyle, mostly in young adults. Physical…”
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Critical Neurological Conditions: Severe Toxic Polyneuropathy with the Development of Respiratory Failure and Rhabdomyolysis by Ryabinkina, Yu. V., Zakharova, M. N., Polishchuk, R. V., Luneva, I. E., Pavlov, E. V., Piradov, M. A.

“…The article describes the clinical case of severe toxic polyneuropathy due to a confirmed exogenous intoxication with amphetamine in a 52-year-old man. The…”
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The effectiveness of herbicides for combating bread windgrass on winter wheat in the Ryazan region by Artemieva, E. A., Zakharova, M. N., Rozhkova, L. V.

“…Herbologists have calculated that in an integrated system for protecting crops from weeds, diseases and insect pests, up to 30% of productivity can be saved by…”
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Brain Regulatory Functions in Adolescents with Signs of Deviant Behavior. An Interdisciplinary Analysis by Machinskaya, R. I., Zakharova, M. N., Lomakin, D. I.

“…We conducted a comparative interdisciplinary study of the brain regulatory functions in adolescents aged 13–16 years with ( n = 82) and without ( n = 125)…”
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