Search Results - "M. M. Lee"

Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice by Quan, W., Hur, K. Y., Lim, Y., Oh, S. H., Lee, J.-C., Kim, K. H., Kim, G. H., Kim, S.-W., Kim, H. L., Lee, M.-K., Kim, K.-W., Kim, J., Komatsu, M., Lee, M.-S.

“…Aims/hypothesis The unfolded protein response (UPR) in endoplasmic reticulum (ER) and autophagy are known to be related. We investigated the role of autophagy…”
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Incidental Bequests and the Choice to Self-Insure Late-Life Risks by Lockwood, Lee M.

“…Despite facing significant uncertainty about their lifespans and health care costs, most retirees do not buy annuities or long-term care insurance. In this…”
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Co‐Transplantation of Bone Marrow‐Derived Endothelial Progenitor Cells Improves Revascularization and Organization in Islet Grafts by Oh, B. J., Oh, S. H., Jin, S. M., Suh, S., Bae, J. C., Park, C. ‐G., Lee, M. ‐S., Lee, M. ‐K., Kim, J. H., Kim, K. ‐W.

“…Bone marrow‐derived early endothelial progenitor cells (BM‐EPCs) are a clinical tool for enhancing revascularization. However, the therapeutic efficacy of…”
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Convergence innovation in the digital age and in the COVID-19 pandemic crisis by Lee, Sang M., Trimi, Silvana

“…•Convergence innovation (CI) as a sustainable core competence.•CI: its concept, autonomous ecosystem, and life cycle.•CI for managing the COVID-19 pandemic.•CI…”
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Improving the accuracy of medical diagnosis with causal machine learning by Richens, Jonathan G., Lee, Ciarán M., Johri, Saurabh

“…Machine learning promises to revolutionize clinical decision making and diagnosis. In medical diagnosis a doctor aims to explain a patient’s symptoms by…”
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Antiangiogenic therapy in oncology: current status and future directions by Jayson, Gordon C, Prof, Kerbel, Robert, Prof, Ellis, Lee M, Prof, Harris, Adrian L, Prof

“…Summary Angiogenesis, the formation of new blood vessels from pre-existing vessels, has been validated as a target in several tumour types through randomised…”
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Roles of p53, Myc and HIF-1 in Regulating Glycolysis - the Seventh Hallmark of Cancer by Yeung, S. J, Pan, J, Lee, M.-H

“…Despite diversity in genetic events in oncogenesis, cancer cells exhibit a common set of functional characteristics. Otto Warburg discovered that cancer cells…”
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The Human Microbiome and Obesity: Moving beyond Associations by Maruvada, Padma, Leone, Vanessa, Kaplan, Lee M., Chang, Eugene B.

“…Mounting evidence indicates that the gut microbiome responds to diet, antibiotics, and other external stimuli with speed and high precision and in ways that…”
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Economic Analyses for Disease Surveillance Planning and Advocacy by Hampton, Lee M

“…Public health disease surveillance can guide a range of decisions related to the protection of populations. Economic analysis can be used to assess how…”
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Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial by Jastreboff, Ania M., Kaplan, Lee M., Frías, Juan P., Wu, Qiwei, Du, Yu, Gurbuz, Sirel, Coskun, Tamer, Haupt, Axel, Milicevic, Zvonko, Hartman, Mark L.

“…In this trial involving participants with obesity, 48 weeks of treatment with retatrutide, an agonist of the GIP, GLP-1, and GCG receptors, resulted in…”
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Association between the extent of urinary albumin excretion and glycaemic variability indices measured by continuous glucose monitoring by Jin, S.-M., Kim, T.-H., Oh, S., Baek, J., Joung, J. Y., Park, S.-M., Cho, Y. Y., Sohn, S. Y., Hur, K. Y., Lee, M.-S., Lee, M.-K., Kim, J. H.

“…Aims The contribution of glycaemic variability to the microvascular complication of diabetes has not been established. We examined whether there is an…”
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Management of Localized Intrahepatic Cholangiocarcinoma: What Exactly is the ‘Evidence’? by Ocuin, Lee M.

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Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing by Caudle, K E, Rettie, A E, Whirl-Carrillo, M, Smith, L H, Mintzer, S, Lee, M T M, Klein, T E, Callaghan, J T

“…Phenytoin is a widely used antiepileptic drug with a narrow therapeutic index and large interpatient variability, partly due to genetic variations in the gene…”
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Z944: A first in class T-type calcium channel modulator for the treatment of pain by Lee, M

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Drug development: Raise standards for preclinical cancer research by Begley, C Glenn, Ellis, Lee M

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Evaluation and Care of Patients with Diabetic Retinopathy by Jampol, Lee M, Glassman, Adam R, Sun, Jennifer

“…Diabetic retinopathy is a leading cause of both moderate and severe vision loss worldwide. Over the past decade, advances in technology have dramatically…”
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Raise standards for preclinical cancer research by Begley, C. Glenn, Ellis, Lee M.

“…C. Glenn Begley and Lee M. Ellis propose how methods, publications and incentives must change if patients are to benefit…”
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Protein transmission in neurodegenerative disease by Peng, Chao, Trojanowski, John Q., Lee, Virginia M.-Y.

“…Most neurodegenerative diseases are characterized by the intracellular or extracellular aggregation of misfolded proteins such as amyloid-β and tau in…”
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Highlight of 2023: The metabolic symphony – orchestrating T‐cell immunity by Booty, Lee M

“…The significance of metabolites in orchestrating immune cells is now recognized to be on par with other key immune modulators, such as cytokines or chemokines…”
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RE: The Blind Men and the Elephant in the Room by Whitesides, Lee M.

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