Search Results - "M. M. Guzyk"

Production of recombinant SARS-COV-2 proteins and diphtheria toxoid CRM197-based fusion by Krynina, O. I., Romaniuk, S. I., Gorbatiuk, O. B., Korchynskyi, O. H., Rebriiev, А. V.

“…The quickly emerged global COVID-19 pandemic raised a desperate need in the development of protecting vaccines targeting this disease. Therefore, a generation…”
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Altered sirtuins 1 and 2 expression in the brain of rats induced by experimental diabetes and the ways of its correction by Guzyk, M. M., Tykhonenko, T. M., Dyakun, K. O., Yanitska, L. V., Pryvrotska, I. B., Kuchmerovska, T. M.

“…The molecular pathogenesis of diabetic encephalopathy (DE), one of the serious complications of diabetes mellitus, is complex. In this study, we examined…”
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Plasminogen modulates formation of reactive oxygen species in human platelets by Tykhomyrov, A. A., Zhernosekov, D. D., Guzyk, M. M., Korsa, V. V., Grinenko, T. V.

“…Reactive oxygen species (ROS) are considered to be important signalling molecules controlling many platelet functions. ROS production has been shown to be…”
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Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling by Zholobak, Nadezhda M, Popov, Anton L, Shcherbakov, Alexander B, Popova, Nelly R, Guzyk, Mykhailo M, Antonovich, Valeriy P, Yegorova, Alla V, Scrypynets, Yuliya V, Leonenko, Inna I, Baranchikov, Alexander Ye, Ivanov, Vladimir K

“…Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the…”
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Glu- and Lys-forms of plasminogen differentially affect phosphatidylserine exposure on the platelet surface by Zhernossekov, D. D., Roka-Moiia, Y. M., Tykhomyrov, A. O., Guzyk, M. M., Grinenko, T. V.

“…Plasminogen/plasmin system is known for its ability to support hemostatic balance of blood. However, plasminogen may be considered as an adhesive ligand and in…”
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Inhibitors of Poly(ADP-Ribose)Polymerase-1 as Agents Providing Correction of Brain Dysfunctions Induced by Experimental Diabetes by Guzyk, M. M., Dyakun, K.O., Yanytska, L. V., Pryvrotska, I. B., Krynytska, I. Ya, Pishel’, I. M., Kuchmerovska, T. M.

“…The effects of 1,5-isoquinolinediol (IQD) and nicotinamide (NAm), inhibitors of poly-(ADP-ribose) polymerase-1 (PARP-1), on inflammatory processes and…”
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Influence of poly(ADP-ribose)polymerase inhibitors on some parameters of oxidative stress in blood leukocytes of rats with experimental diabetes by M. M. Guzyk, K. O. Dyakun, L. V. Yanitska, Т. М. Kuchmerovska

“…The study was undertaken to investigate the influence of specific inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1), in particular nicotinamide and…”
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FEATURES OF USING ORTHOPEDIC IMPLANTS ON AN EXPERIMENTAL MODEL OF SENSITIZATION TO NICKEL (NI) by Lazarenko, Hlib O., Savosko, Serhii I., Guzyk, Mykhailo M., Boiko, Igor V.

“…Introduction. The theme of metal hypersensitivity (MHS) reactions is among the most controversial and complex issues in orthopedic and trauma practice. MHS…”
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State of Astrocytes in the Mice Brain under Conditions of Herpes Viral Infection and Modeled Stroke by Gumenyuk, A. V., Tykhomyrov, A. A., Savosko, S. I., Guzyk, M. M., Rybalko, S. L., Ryzha, А. О., Chaikovsky, Yu. B.

“…Changes in astrocytes of the mice brain induced by infection with herpes simplex virus type 1 (HSV-1) and modeling of hemorrhagic stroke were examined by…”
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doi: http://dx.doi.org/10.15407/ubj86.04.138 by M. M. Guzyk, Iu. T. Sergiichuk, K. O. Dyakun, L. V. Yanitska, T. M. Kuchmerovska

“…Connective tissue is highly susceptible to imbalances induced by diabetes. Diabetes-related osteopenia, decreased bone strength etc. may be associated with…”
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OP13: The effect of poly(ADP-ribose)polymerase inhibitors on diabetes-induced heart dysfunctions by Kuchmerovska, T, Guzyk, M, Yanitska, L, Pentek, I, Diakun, K

“…Background and aims Incidence of cardiovascular (CV) events is increased in type 2 diabetes (T2D) but the potential for CV risk modulation with glucose…”
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Effect of combined nicotinamide, acetyl-L-carnitine and α-lipoic acid action on separate links of carbohydrate metabolism under experimental type 2 diabetes by Sergiichuk, Iu. T., Tykhonenko, T. M., Guzyk, M. M., Yanitska, L. V., Kuchmerovska, T. M.

“…The effect of nicotinamide, acetyl-L-carnitine and α-lipoic acid on the separate links of carbohydrate metabolism in the brain, heart and liver of rats for…”
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GFAP as a marker of reactive astrocytes in the mice brain following hemorrhagic stroke and HSV-I by Gumenyuk, A. V., Rybalko, S. L., Savosko, S. I., Guzyk, M. M., Tykhomyrov, A. O., Ryzha, A. A., Chaikovsky, Yu. B.

“…Aim. To investigate reactive changes of GFAP-positive astrocytes as a marker of brain response following hemorrhagic stroke and HSV-I. Methods. The experiments…”
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Effect of nicotinamide on amino acids content in bone collagen depending on biological availability of vitamins in diabetic rats by Guzyk, M M, Sergiichuk, Iu T, Dyakun, K O, Yanitska, L V, Kuchmerovska, T M

“…Connective tissue is highly susceptible to imbalances induced by diabetes. Diabetes-related osteopenia, decreased bone strength etc. may be associated with…”
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Poly(ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors Reduce Reactive Gliosis and Improve Angiostatin Levels in Retina of Diabetic Rats by Guzyk, Mykhailo M., Tykhomyrov, Artem A., Nedzvetsky, Victor S., Prischepa, Irina V., Grinenko, Tatiana V., Yanitska, Lesya V., Kuchmerovska, Tamara M.

“…Diabetic retinopathy (DR) is a multifactorial disease characterized by reactive gliosis and disbalance of angiogenesis regulators, contributing to endothelial…”
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P.114 Effects of nicotinoyl gamma-aminobutyric acid on brain cytoskeleton and myelin basic protein levels in diabetic rats by Tykhonenko, T., Tykhomyrov, A., Guzyk, M., Dyakun, K., Kuchmerovska, T.

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P.834 The effects of nicotinamide on the brain functional protein markers in prevention of diabetic neuropathy by Tykhonenko, T., Tykhomyrov, A., Guzyk, M., Dyakun, K., Kuchmerovska, T.

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The study of leukocyte phagocytic activity in the presence of herpetic infection and stroke by Motorna, Natalia V, Rybalko, Svetlana L, Starosyla, Daria B, Guzyk, Mykhailo M, Strokina, Iryna G, Kaminsky, Rostyslav F, Korsak, Alina V, Savosko, Sergey I, Sokurenko, Liudmyla M, Chaikovsky, Yurii B

“…Inrtoduction: Post-stroke complications are one of the urgent and insufficiently resolved problems. According to different literature data 23% to 65% of…”
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Effects of a Combined Mitochondria-Targeted Treatment on the State of Mitochondria and Synaptic Membranes from the Brains of Diabetic Rats by Kuchmerovska, T. M., Dyakun, K. O., Guzyk, M. M., Yanytska, L. V., Pryvrotska, I. B.

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Effect of insulin-like growth factor transgene on wound healing in mice with streptozotocin-induced diabetes by Leonov, Yu. I., Shkumat, M. S., Klymenko, P. P., Hovorun, M. Yu, Guzyk, M. M., Kuchmerovska, T. M., Pishel, I. M.

“…Insulin-like growth factor 1 (IGF-1) is one of the main factors that can affect the condition and rate of skin regeneration process. Morphological and…”
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