Search Results - "M. Grote"

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1 by Mouro Pinto, Ricardo, Arning, Larissa, Giordano, James V, Razghandi, Pedram, Andrew, Marissa A, Gillis, Tammy, Correia, Kevin, Mysore, Jayalakshmi S, Grote Urtubey, Debora-M, Parwez, Constanze R, von Hein, Sarah M, Clark, H Brent, Nguyen, Huu Phuc, Förster, Eckart, Beller, Allison, Jayadaev, Suman, Keene, C Dirk, Bird, Thomas D, Lucente, Diane, Vonsattel, Jean-Paul, Orr, Harry, Saft, Carsten, Petrasch-Parwez, Elisabeth, Wheeler, Vanessa C

“…Abstract The expanded HTT CAG repeat causing Huntington’s disease (HD) exhibits somatic expansion proposed to drive the rate of disease onset by eliciting a…”
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TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin’s lymphoma by Yang, Z-Z, Grote, D M, Xiu, B, Ziesmer, S C, Price-Troska, T L, Hodge, L S, Yates, D M, Novak, A J, Ansell, S M

“…Transforming growth factor beta (TGF-β) has an important role in mediating T-cell suppression in B-cell non-Hodgkin lymphoma (NHL). However, the underlying…”
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Targeting orphan G protein‐coupled receptors for the treatment of diabetes and its complications: C‐peptide and GPR146 by Kolar, G. R., Grote, S. M., Yosten, G. L. C.

“…G protein‐coupled receptors (GPCRs) are the most abundant receptor family encoded by the human genome and are the targets of a high percentage of drugs…”
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Antibodies induced with recombinant VP1 from human rhinovirus exhibit cross-neutralisation by Edlmayr, J, Niespodziana, K, Popow-Kraupp, T, Krzyzanek, V, Focke-Tejkl, M, Blaas, D, Grote, M, Valenta, R

“…Human rhinoviruses (HRVs) are the major cause of the common cold and account for 30-50% of all acute respiratory illnesses. Although HRV infections are usually…”
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Soluble and membrane-bound TGF-β-mediated regulation of intratumoral T cell differentiation and function in B-cell non-Hodgkin lymphoma by Yang, Zhi-Zhang, Grote, Deanna M, Ziesmer, Steven C, Xiu, Bing, Yates, Nicole R, Secreto, Frank J, Hodge, Lucy S, Witzig, Thomas E, Novak, Anne J, Ansell, Stephen M

“…While the effect of TGF-β on malignant B cells in non-Hodgkin lymphoma (NHL) has been previously evaluated, studies to specifically define the role of TGF-β in…”
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Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity by Elsawa, Sherine F., Novak, Anne J., Ziesmer, Steven C., Almada, Luciana L., Hodge, Lucy S., Grote, Deanna M., Witzig, Thomas E., Fernandez-Zapico, Martin E., Ansell, Stephen M.

“…Although proinflammatory and chemotactic cytokines can profoundly affect the tumor microenvironment, and many of them have been shown to have therapeutic…”
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Impact of a recent wildfire on tortoises at Cape Point, South Africa, and implications for the interpretation of heated bones in the archaeological record by Stahlschmidt, M. C., Mentzer, S. M., Heinrich, S., Cooper, A., Grote, M. N., McNeill, P. J., Wilder, J. C.-B., Steele, T. E.

“…Heat-altered bones are a common occurrence in the archaeological record, and their analysis can provide detailed insights into past fire use behaviors and…”
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Flexible enzymatic activation of artificial polyketide extender units by Streptomyces cinnamonensis into the monensin biosynthetic pathway by Möller, D., Kushnir, S., Grote, M., Ismail‐Ali, A., Koopmans, K.R.M., Calo, F., Heinrich, S., Diehl, B., Schulz, F.

“…Streptomyces cinnamonensis A495 is a variant of the monensin producer which instead of the native polyether antibiotic gives rise to antibiotic and anti‐tumour…”
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Characterization of Der p 21, a new important allergen derived from the gut of house dust mites by Weghofer, M, Dall'Antonia, Y, Grote, M, Stöcklinger, A, Kneidinger, M, Balic, N, Krauth, M.-T, Fernández-Caldas, E, Thomas, W.R, Hage, M. van, Vieths, S, Spitzauer, S, Horak, F, Svergun, D.I, Konarev, P.V, Valent, P, Thalhamer, J, Keller, W, Valenta, R, Vrtala, S

“…The house dust mite (HDM) Dermatophagoides pteronyssinus is a major allergen source eliciting allergic asthma. The aim of the study was to identify new…”
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Establishment and characterization of a novel Waldenström macroglobulinemia cell line, MWCL-1 by Hodge, Lucy S., Novak, Anne J., Grote, Deanna M., Braggio, Esteban, Ketterling, Rhett P., Manske, Michelle K., Price Troska, Tammy L., Ziesmer, Steven C., Fonseca, Rafael, Witzig, Thomas E., Morice, William G., Gertz, Morie A., Ansell, Stephen M.

“…Waldenström macroglobulinemia (WM) is a rare, lymphoplasmacytic lymphoma characterized by hypersecretion of immunoglobulin M (IgM) protein and tumor…”
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Experimental and computational investigations of a compact steam reformer for fuel oil and diesel fuel by Grote, M., Maximini, M., Yang, Z., Engelhardt, P., Köhne, H., Lucka, K., Brenner, M.

“…The present work describes the optimisation of a compact steam reformer for light fuel oil and diesel fuel. The reformer is based upon a catalytically coated…”
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An Enantioselective Synthesis of (S)-(+)-3-Aminomethyl-5-methylhexanoic Acid via Asymmetric Hydrogenation by Burk, Mark J, de Koning, Pieter D, Grote, Todd M, Hoekstra, Marvin S, Hoge, Garrett, Jennings, Rex A, Kissel, William S, Le, Tung V, Lennon, Ian C, Mulhern, Thomas A, Ramsden, James A, Wade, Robert A

“…A concise enantioselective synthesis of (S)-(+)-3-aminomethyl-5-methylhexanoic acid (1, Pregabalin) has been developed. The key step is the asymmetric…”
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Quantification of cell surface proteins with bispecific antibodies by Panke, C., Weininger, D., Haas, A., Schelter, F., Schlothauer, T., Bader, S., Sircar, R., Josel, H.P., Baer, U., Burtscher, H., Mundigl, O., Grote, M., Brinkmann, U., Sustmann, C.

“…Flow cytometry is an established method for fast and accurate quantitation of cellular protein levels and requires fluorescently labeled antibodies as well as…”
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Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma by Ansell, S M, Tang, H, Kurtin, P J, Koenig, P A, Nowakowski, G S, Nikcevich, D A, Nelson, G D, Yang, Z, Grote, D M, Ziesmer, S C, Silberstein, P T, Erlichman, C, Witzig, T E

“…Follicular lymphoma exhibits intratumoral infiltration by non-malignant T lymphocytes, including CD4+CD25+ regulatory T (T reg ) cells. We combined denileukin…”
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Elevated Serum B-Lymphocyte Stimulator Levels in Patients With Familial Lymphoproliferative Disorders by NOVAK, Anne J, GROTE, Deanna M, JELINEK, Diane F, CERHAN, James R, GROSS, Jane A, HARDER, Brandon, DILLON, Stacey R, ANSELL, Stephen M, ZIESMER, Steven C, KLINE, Michael P, MANSKE, Michelle K, SLAGER, Susan, WITZIG, Thomas E, SHANAFELT, Tail, CALL, Timothy G, KAY, Neil E

“…Serum B-lymphocyte stimulator (BLyS) levels have been found to be elevated in a number of immune disease models. Therefore, we sought to establish whether BLyS…”
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Secretion of recombinant proteins from E. coli by Kleiner‐Grote, Gabriele R. M., Risse, Joe M., Friehs, Karl

“…The microorganism Escherichia coli is commonly used for recombinant protein production. Despite several advantageous characteristics like fast growth and high…”
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Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: correlation with disease activity and patient outcome by Novak, Anne J., Grote, Deanna M., Stenson, Mary, Ziesmer, Steven C., Witzig, Thomas E., Habermann, Thomas M., Harder, Brandon, Ristow, Kay M., Bram, Richard J., Jelinek, Diane F., Gross, Jane A., Ansell, Stephen M.

“…BLyS, recently shown to be critical for survival of normal B cells, has been found to be elevated in a number of immune disease models. A role for BLyS in the…”
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Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma by ANSELL, S. M, ARENDT, B. K, GROTE, D. M, JELINEK, D. F, NOVAK, A. J, WELLIK, L. E, REMSTEIN, E. D, BENNETT, C. F, FIELDING, A

“…Survivin is a member of the inhibitor of apoptosis protein (IAP) family and functions both as an apoptosis inhibitor and a regulator of cell division. Survivin…”
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IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma by Yang, Zhi-Zhang, Grote, Deanna M, Ziesmer, Steven C, Niki, Toshiro, Hirashima, Mitsuomi, Novak, Anne J, Witzig, Thomas E, Ansell, Stephen M

“…The cytokine IL-12 induces IFN-γ production by T and NK cells. In preclinical models, it contributes to antitumor immunity. However, in clinical testing, it…”
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Describing Maize (Zea mays L.) Landrace Persistence in the Bajío of Mexico: A Survey of 1940s and 1950s Collection Locations by Chambers, K. J, Brush, S. B, Grote, M. N, Gepts, P

“…Passport data for Mexico's Guanajuato State were used to locate the sites where maize was collected in the 1940s and 1950s in an effort to document and…”
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