Search Results - "M. Goergen"
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The DNA Cytosine Deaminase APOBEC3B is a Molecular Determinant of Platinum Responsiveness in Clear Cell Ovarian Cancer
Published in Clinical cancer research (01-07-2020)“…Clear cell ovarian carcinoma (CCOC) is an aggressive disease that often demonstrates resistance to standard chemotherapies. Approximately 25% of patients with…”
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Similar humoral responses but distinct CD4+ T cell transcriptomic profiles in older adults elicited by MF59 adjuvanted and high dose influenza vaccines
Published in Scientific reports (18-10-2024)“…Older age (≥ 65 years) is associated with impaired responses to influenza vaccination, leading to the preferential recommendation of MF59-adjuvanted (MF59Flu)…”
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Sex Differences in Older Adults' Immune Responses to Seasonal Influenza Vaccination
Published in Frontiers in immunology (27-02-2019)“…Sex differences in immune responses to influenza vaccine may impact efficacy across populations. In a cohort of 138 older adults (50-74 years old), we measured…”
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Diagnostic and prognostic potential of the microbiome in ovarian cancer treatment response
Published in Scientific reports (13-01-2023)“…Ovarian cancer (OC) is the second most common gynecological malignancy and the fifth leading cause of death due to cancer in women in the United States mainly…”
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Differential miRNA expression in B cells is associated with inter-individual differences in humoral immune response to measles vaccination
Published in PloS one (30-01-2018)“…MicroRNAs are important mediators of post-transcriptional regulation of gene expression through RNA degradation and translational repression, and are emerging…”
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Virus-specific and shared gene expression signatures in immune cells after vaccination in response to influenza and vaccinia stimulation
Published in Frontiers in immunology (04-08-2023)“…In the vaccine era, individuals receive multiple vaccines in their lifetime. Host gene expression in response to antigenic stimulation is usually…”
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T Cell Transcriptional Signatures of Influenza A/H3N2 Antibody Response to High Dose Influenza and Adjuvanted Influenza Vaccine in Older Adults
Published in Viruses (01-12-2022)“…Older adults experience declining influenza vaccine-induced immunity and are at higher risk of influenza and its complications. For this reason, high dose…”
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The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects
Published in PloS one (27-03-2015)“…Although influenza causes significant morbidity and mortality in the elderly, the factors underlying the reduced vaccine immunogenicity and efficacy in this…”
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Native Perennial Grasses Show Evolutionary Response to Bromus tectorum (Cheatgrass) Invasion
Published in PloS one (30-03-2011)“…Invasive species can change selective pressures on native plants by altering biotic and abiotic conditions in invaded habitats. Although invasions can lead to…”
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Statistical analysis of comparative tumor growth repeated measures experiments in the ovarian cancer patient derived xenograft (PDX) setting
Published in Scientific reports (13-04-2021)“…Repeated measures studies are frequently performed in patient-derived xenograft (PDX) models to evaluate drug activity or compare effectiveness of cancer…”
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Plant-Soil Feedbacks Contribute to the Persistence of Bromus inermis in Tallgrass Prairie
Published in Ecosystems (New York) (01-09-2006)“…As invasive plants become a greater threat to native ecosystems, we need to improve our understanding of the factors underlying their success and persistence…”
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Transthoracic Echocardiography versus Computed Tomography for Ascending Aortic Measurements in Patients with Bicuspid Aortic Valve
Published in Journal of the American Society of Echocardiography (01-07-2017)“…Background Ascending aorta dilatation is common in bicuspid aortic valve (BAV). The aim of this study was to investigate agreement of transthoracic…”
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EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review
Published in Genes & cancer (01-05-2017)“…Limited effectiveness of therapeutic agents targeting epidermal growth factor receptor (EGFR) in clinical trials using unselected ovarian cancer patients has…”
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Utility of Progranulin and Serum Leukocyte Protease Inhibitor as Diagnostic and Prognostic Biomarkers in Ovarian Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-10-2013)“…Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer-related death in females and leading gynecologic cause of cancer-related death. Despite…”
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Laparoscopic ultralow anterior resection with intersphincteric dissection and delayed coloanal anastomosis in the TaTME era – a video vignette
Published in Colorectal disease (01-08-2018)Get full text
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Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults
Published in Frontiers in aging (20-08-2021)“…Introduction: Each year, a disproportionate number of the total seasonal influenza-related hospitalizations (90%) and deaths (70%) occur among adults who are…”
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Integration of Immune Cell Populations, mRNA-Seq, and CpG Methylation to Better Predict Humoral Immunity to Influenza Vaccination: Dependence of mRNA-Seq/CpG Methylation on Immune Cell Populations
Published in Frontiers in immunology (21-04-2017)“…The development of a humoral immune response to influenza vaccines occurs on a multisystems level. Due to the orchestration required for robust immune…”
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Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers
Published in Oncotarget (03-11-2015)“…Ovarian cancer represents the most lethal tumor type among malignancies of the female reproductive system. Overall survival rates remain low. In this study, we…”
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Corporate Governance Convergence: Evidence From Takeover Regulation Reforms in Europe
Published in Oxford review of economic policy (01-07-2005)“…This paper contributes to the research on corporate governance by predicting the effects of European takeover regulation. In particular, we investigate whether…”
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Laparoscopic liver resection of benign liver tumors: Results of a multicenter european experience
Published in Surgical endoscopy (2003)Get full text
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