Search Results - "M. G. Shankar"

Syntheses, crystal structures, Hirshfeld surface analyses and energy frameworks of two 4-aminoantipyrine Schiff base compounds: (E)-4-{[4-(diethylamino)benzylidene]amino}-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one and (E)-4-[(4-fluorobenzylidene)amino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one by M. G. Shankar, R. Kumaravel, A. Subashini, K. Ramamurthi, Monika Kučeráková, Michal Dušek, Helen Stoeckli-Evans

“…The title Schiff base compounds, C22H26N4O (I) and C18H16FN3O (II), were each synthesized by a single-step condensation reaction. The substituted benzylidene…”
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Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo by Selkoe, Dennis J, Rowan, Michael J, Klyubin, Igor, Walsh, Dominic M, Lemere, Cynthia A, Cullen, William K, Shankar, Ganesh M, Betts, Vicki, Spooner, Edward T, Jiang, Liying, Anwyl, Roger

“…One of the most clinically advanced forms of experimental disease-modifying treatment for Alzheimer disease is immunization against the amyloid β protein (Aβ),…”
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Syntheses, crystal structures, Hirshfeld surface analyses and energy frameworks of two 4-aminoantipyrine Schiff base compounds: ( E )-4-{[4-(diethylamino)benzylidene]amino}-1,5-dimethyl-2-phenyl-1 H -pyrazol-3(2 H )-one and ( E )-4-[(4-fluorobenzylidene)amino]-1,5-dimethyl-2-phenyl-1 H -pyrazol-3(2 H )-one by Shankar, M. G., Kumaravel, R., Subashini, A., Ramamurthi, K., Kučeráková, Monika, Dušek, Michal, Stoeckli-Evans, Helen

“…The title Schiff base compounds, C 22 H 26 N 4 O ( I ) and C 18 H 16 FN 3 O ( II ), were each synthesized by a single-step condensation reaction. The…”
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Syntheses, crystal structures, Hirshfeld surface analyses and energy frameworks of two 4-amino-anti-pyrine Schiff base compounds: (E)-4-{4-(di-ethyl-amino)-benzyl-ideneamino}-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one and (E)-4-(4-fluoro-benzyl-idene)amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one by Shankar, M G, Kumaravel, R, Subashini, A, Ramamurthi, K, Kučeráková, Monika, Dušek, Michal, Stoeckli-Evans, Helen

“…The title Schiff base compounds, C22H26N4O (I) and C18H16FN3O (II), were each synthesized by a single-step condensation reaction. The substituted benzyl-idene…”
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Syntheses, crystal structures, Hirshfeld surface analyses and energy frameworks of two 4-amino-anti-pyrine Schiff base compounds: ( E )-4-{[4-(di-ethyl-amino)-benzyl-idene]amino}-1,5-dimethyl-2-phenyl-1 H -pyrazol-3(2 H )-one and ( E )-4-[(4-fluoro-benzyl-idene)amino]-1,5-dimethyl-2-phenyl-1 H -pyrazol-3(2 H )-one by Shankar, M G, Kumaravel, R, Subashini, A, Ramamurthi, K, Kučeráková, Monika, Dušek, Michal, Stoeckli-Evans, Helen

“…The title Schiff base compounds, C H N O ( ) and C H FN O ( ), were each synthesized by a single-step condensation reaction. The substituted benzyl-idene ring…”
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Syntheses, crystal structures, Hirshfeld surface analyses and energy frameworks of two 4-amino­anti­pyrine Schiff base compounds: (E)-4-{[4-(di­ethyl­amino)­benzyl­idene]amino}-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one and (E)-4-[(4-fluoro­benzyl­idene)amino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one by Shankar, M. G., Kumaravel, R., Subashini, A., Ramamurthi, K., Kučeráková, Monika, Dušek, Michal, Stoeckli-Evans, Helen

“…The title 4-amino­anti­pyrine Schiff base compounds both deviate from planarity with the phenyl ring and the substituted benzyl­idene ring being inclined to…”
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P06.11.B NEUROTOXICITY AND MANAGEMENT OF PRIMARY AND SECONDARY CNS LYMPHOMA AFTER ADOPTIVE IMMUNOTHERAPY WITH CD19-DIRECTED CAR T-CELLS by Karschnia, P, Arrillaga-Romany, I C, Eichler, A, Forst, D A, Gerstner, E, Jordan, J T, Ly, I, Plotkin, S R, Wang, N, Martinez-Lage, M, Winter, S F, Tonn, J, Rejeski, K, von Baumgarten, L, Cahill, D P, Nahed, B V, Shankar, G M, Abramson, J S, Barnes, J A, El-Jawahri, A, Hochberg, E P, Johnson, P, Soumerai, J D, Takvorian, R W, Chen, Y, Frigault, M J, Dietrich, J

“…Abstract BACKGROUND Chimeric antigen receptor (CAR) T-cells targeting CD19 have been established as a leading engineered T-cell therapy for systemic B-cell…”
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Loss of Neprilysin Function Promotes Amyloid Plaque Formation and Causes Cerebral Amyloid Angiopathy by Farris, Wesley, Schütz, Sonja G, Cirrito, John R, Shankar, Ganesh M, Sun, Xiaoyan, George, Ana, Leissring, Malcolm A, Walsh, Dominic M, Qiu, Wei Qiao, Holtzman, David M, Selkoe, Dennis J

“…Cerebral deposition of the amyloid β protein (Aβ), an invariant feature of Alzheimer's disease, reflects an imbalance between the rates of Aβ production and…”
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Effects of secreted oligomers of amyloid β‐protein on hippocampal synaptic plasticity: a potent role for trimers by Townsend, Matthew, Shankar, Ganesh M., Mehta, Tapan, Walsh, Dominic M., Selkoe, Dennis J.

“…The accumulation of amyloid β‐protein (Aβ) in brain regions serving memory and cognition is a central pathogenic feature of Alzheimer's disease (AD). We have…”
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Natural oligomers of the amyloid-[beta] protein specifically disrupt cognitive function by Cleary, James P, Walsh, Dominic M, Hofmeister, Jacki J, Shankar, Ganesh M, Kuskowski, Michael A, Selkoe, Dennis J, Ashe, Karen H

“…A central unresolved problem in research on Alzheimer disease is the nature of the molecular entity causing dementia. Here we provide the first direct…”
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Certain Inhibitors of Synthetic Amyloid β-Peptide (Aβ) Fibrillogenesis Block Oligomerization of Natural Aβ and Thereby Rescue Long-Term Potentiation by Walsh, Dominic M., Townsend, Matthew, Podlisny, Marcia B., Shankar, Ganesh M., Fadeeva, Julia V., Agnaf, Omar El, Hartley, Dean M., Selkoe, Dennis J.

“…Recent studies support the hypothesis that soluble oligomers of amyloid β-peptide (Aβ) rather than mature amyloid fibrils are the earliest effectors of…”
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A stability-indicating LC–MS/MS method for zidovudine: Identification,characterization and toxicity prediction of two major acid degradation products by Devrukhakar, Prashant S., Shiva Shankar, M., Shankar, G., Srinivas, R.

“…Zidvovudine (AZT) is a nucleoside analogue reverse transcriptase inhibitor (NRTI), a class of anti-retroviral drug. A stability-indicating assay method for AZT…”
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The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention by Walsh, D M, Klyubin, I, Shankar, G M, Townsend, M, Fadeeva, J V, Betts, V, Podlisny, M B, Cleary, J P, Ashe, K H, Rowan, M J, Selkoe, D J

“…Burgeoning evidence suggests that soluble oligomers of Abeta (amyloid beta-protein) are the earliest effectors of synaptic compromise in Alzheimer's disease…”
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Green leaf manuring as an alternative nitrogen source for castor bean on marginal soils of India by Reddy, G. Subba, Venkateswarlu, B., Vittal, K. P. R., Shankar, G. R. M.

“…Chemical fertilizers are used only in a limited way under dry farming conditions in India because of their high cost and the risk of crop failures due to…”
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