Search Results - "M. Chieppa"

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning by Iliev, I D, Mileti, E, Matteoli, G, Chieppa, M, Rescigno, M

“…Intestinal dendritic cells (DCs) have been shown to display specialized functions, including the ability to promote gut tropism to lymphocytes, to polarize…”
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Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction by Matteoli, Gianluca, Mazzini, Elisa, Iliev, Iliyan D, Mileti, Erika, Fallarino, Francesca, Puccetti, Paolo, Chieppa, Marcello, Rescigno, Maria

“…CD103(+) gut dendritic cells (DCs) have been shown to be required for de novo conversion of adaptive T regulatory (Treg) cells. Indoleamine 2,3-dioxygenase…”
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Engagement of the Mannose Receptor by Tumoral Mucins Activates an Immune Suppressive Phenotype in Human Tumor-Associated Macrophages by Mantovani, Alberto, Fabbri, M., Solinas, G., Bianchi, G., Chieppa, M., Allavena, P., Laskarin, G.

“…Tumor-Associated Macrophages (TAMs) are abundantly present in the stroma of solid tumors and modulate several important biological processes, such as…”
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Gut microbiota, probiotics and colorectal cancer: a tight relation by A. Pino, M. De Angelis, M. Chieppa, C. Caggia, C. Randazzo

“…Objective: Colorectal cancer is one of the most frequently diagnosed cancers worldwide. Scientific evidence suggests a relationship between gut microbiota and…”
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TNFα deficiency results in increased IL-1β in an early onset of spontaneous murine colitis by De Santis, S, Kunde, D, Galleggiante, V, Liso, M, Scandiffio, L, Serino, G, Pinto, A, Campiglia, P, Sorrentino, R, Cavalcanti, E, Santino, A, Caruso, M L, Eri, R, Chieppa, M

“…Inflammatory bowel disease (Crohn’s disease (CD) and ulcerative colitis (UC)) is a multifactorial disease resulting from immune dysregulation in the gut. The…”
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Chlamydia abortus in Cows Oviducts, Occasional Event or Causal Connection? by Appino, S, Vincenti, L, Rota, A, Pellegrini, S, Chieppa, MN, Cadoni, V, Pregel, P

“…Fifty‐seven genital tracts of regularly slaughtered culled Piedmontese cows, aged 7.4 ± 4.3 years (mean ± SD), range: 2.6–15.6 years, were grossly and…”
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Modeling amyotrophic lateral sclerosis in hSOD1 transgenic swine by Chieppa, M N, Perota, A, Corona, C, Grindatto, A, Lagutina, I, Vallino Costassa, E, Lazzari, G, Colleoni, S, Duchi, R, Lucchini, F, Caramelli, M, Bendotti, C, Galli, C, Casalone, C

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that occurs in two clinically indistinguishable forms: sporadic (SALS) and familial…”
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An extended vision for dynamic high-resolution intravital immune imaging by Germain, Ronald N., Castellino, Flora, Chieppa, Marcello, Egen, Jackson G., Huang, Alex Y.C., Koo, Lily Y., Qi, Hai

“…The past few years have seen the application of confocal and especially two-photon microscopy to the dynamic high-resolution imaging of lymphocytes and antigen…”
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Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells by Rescigno, Maria, Rimoldi, Monica, Chieppa, Marcello, Salucci, Valentina, Avogadri, Francesca, Sonzogni, Angelica, Sampietro, Gianluca M, Nespoli, Angelo, Viale, Giuseppe, Allavena, Paola

“…The control of damaging inflammation by the mucosal immune system in response to commensal and harmful ingested bacteria is unknown. Here we show epithelial…”
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Interactions among dendritic cells, macrophages, and epithelial cells in the gut: implications for immune tolerance by Rescigno, Maria, Lopatin, Uri, Chieppa, Marcello

“…The intestine is described as an immune privileged site where immunoregulatory mechanisms simultaneously defend against pathogens, yet preserve tissue…”
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Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin) : Inhibition of macrophage differentiation and cytokine production by ALLAVENA, Paola, SIGNORELLI, Mauro, DE BRAUD, Filippo, JIMENO, José, D'INCALCI, Maurizio, CHIEPPA, Marcello, ERBA, Eugenio, BIANCHI, Giancarlo, MARCHESI, Federica, OLIMPIO, Chiara Omero, BONARDI, Claudia, GARBI, Annalisa, LISSONI, Andrea

“…Yondelis (Trabectedin) is a novel antitumor agent of marine origin extracted from the tunicate Ecteinascidia turbinata. This original compound is active…”
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Cross-Linking of the Mannose Receptor on Monocyte-Derived Dendritic Cells Activates an Anti-Inflammatory Immunosuppressive Program by Chieppa, Marcello, Bianchi, Giancarlo, Doni, Andrea, Del Prete, Annalisa, Sironi, Marina, Laskarin, Gordana, Monti, Paolo, Piemonti, Lorenzo, Biondi, Andrea, Mantovani, Alberto, Introna, Martino, Allavena, Paola

“…Immature monocyte-derived dendritic cells (DC) strongly express the endocytic mannose receptor (MR). Addition of a specific anti-MR mAb (clone PAM-1) for 24 h…”
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Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different by Rimoldi, Monica, Chieppa, Marcello, Larghi, Paola, Vulcano, Marisa, Allavena, Paola, Rescigno, Maria

“…Dendritic cells (DCs) are able to open the tight junctions between adjacent epithelial cells (ECs) and to take up both invasive and noninvasive bacteria…”
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Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells by Doni, Andrea, Peri, Giuseppe, Chieppa, Marcello, Allavena, Paola, Pasqualini, Fabio, Vago, Luca, Romani, Luigina, Garlanda, Cecilia, Mantovani, Alberto

“…PTX3 is a prototypic of long pentraxin consisting of an N‐terminal portion coupled to a C‐terminal pentraxin domain, the latter related to short pentraxins…”
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P095 Influence of early environmental factors on the establishment of gut microbiome composition, function, and metabolomics profiles in infants at risk of Celiac disease by Valitutti, F., Leonard, M., Montuori, M., Francavilla, R., Malamisura, B., Piemontese, P., Elli, L., Calvi, A., Baldassarre, M., Norsa, L., Trovato, C.M., Raguseo, L., Kenyon, V., Passaro, T., Roggero, P., Crocco, M., Chieppa, M., Troisi, J., Scala, G., Lionetti, M.E., Catassi, C., Cucchiara, S., Fasano, A.

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Gut-level decisions in peace and war by Rescigno, Maria, Chieppa, Marcello

“…The gut contains most of the immune cells in the body, yet fights off bacteria only if they are pathogenic, leaving commensal microbes largely unscathed. Two…”
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Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses by Fraticelli, P, Sironi, M, Bianchi, G, D'Ambrosio, D, Albanesi, C, Stoppacciaro, A, Chieppa, M, Allavena, P, Ruco, L, Girolomoni, G, Sinigaglia, F, Vecchi, A, Mantovani, A

“…Fractalkine (FKN, CX3CL1) is a membrane-bound CX3C chemokine induced by primary proinflammatory signals in vascular endothelial cells (ECs). Here we examined…”
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From pattern recognition receptor to regulator of homeostasis: the double-faced macrophage mannose receptor by Allavena, Paola, Chieppa, Marcello, Monti, Paolo, Piemonti, Lorenzo

“…The mannose receptor (MR) is an endocytic and phagocytic receptor belonging to the C-type lectin superfamily. A number of functions have been ascribed to this…”
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Effects of erythromycin on human colonic circular muscle in idiopathic chronic constipation by CHIEPPA, D. M, MANSI, G, ALTOMARE, D. F, RINALDI, R, SERIO, M, NACCI, C, MONTAGNANI, M, POTENZA, M. A, DE SALVIA, M. A, MITOLO, C. I, RINALDI, M

“…Background Erythromycin has been shown to have profound prokinetic effects on the gastrointestinal tract of humans and animals, probably through its action on…”
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Modification of Lipid Profile in Commercial Cow Milk Samples before and after Their Expiration Date: Evaluation of Storage Crucial Parameters and Possible Environmentally Friendly Disposal Alternatives by Pepe, Giacomo, Campiglia, Pietro, Vitale, Andrea, Ostacolo, Carmine, Mastrocinque, Raffaella, Manfra, Michele, Tenore, Gian Carlo, Basilicata, Manuela Giovanna, Sommella, Eduardo, Chieppa, M.

“…Milk waste is considered a highly polluting material and its disposal is an economic and environmental problem for the dairy sector. Despite this, it can be…”
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