Search Results - "M. A. Lagarkova"

Development of Hematopoietic Stem Cells in the Early Mammalian Embryo by Rybtsov, S. A., Lagarkova, M. A.

“…Hematopoietic stem cells (HSCs) were the first stem cells discovered in humans. A. A. Maximov proposed an idea of blood stem cells that was confirmed later by…”
Get full text

Patient-Specific Induced Pluripotent Stem Cells for SOD1-Associated Amyotrophic Lateral Sclerosis Pathogenesis Studies by Chestkov, I V, Vasilieva, E A, Illarioshkin, S N, Lagarkova, M A, Kiselev, S L

“…The genetic reprogramming technology allows one to generate pluripotent stem cells for individual patients. These cells, called induced pluripotent stem cells…”
Get full text

Such Various Stem Cells by Lagarkova, M. A.

“…Perhaps there is no more intriguing topic in modern biology than stem cells. The growing interest in stem cells is dictated by the ability of stem cells to…”
Get full text

Pluripotent Stem Cells for Modelling and Cell Therapy of Parkinson’s Disease by Lebedeva, O. S., Lagarkova, M. A.

“…Studying pathogenesis of neurodegenerative diseases, including Parkinson’s disease (PD), requires adequate disease models. The available patient’s material is…”
Get full text

Molecular barriers to processes of genetic reprogramming and cell transformation by Chestkov, I. V., Khomyakova, E. A., Vasilieva, E. A., Lagarkova, M. A., Kiselev, S. L.

“…Genetic reprogramming by ectopic expression of transcription factor genes induces the pluripotent state in somatic cells. This technology provides an…”
Get full text

No DNA damage response and negligible genome-wide transcriptional changes in human embryonic stem cells exposed to terahertz radiation by Bogomazova, A. N., Vassina, E. M., Goryachkovskaya, T. N., Popik, V. M., Sokolov, A. S., Kolchanov, N. A., Lagarkova, M. A., Kiselev, S. L., Peltek, S. E.

“…Terahertz (THz) radiation was proposed recently for use in various applications, including medical imaging and security scanners. However, there are concerns…”
Get full text

Derivation of induced pluripotent stem cells line (RCPCMi007-A-1) with inactivation of the beta-2-microglobulin gene by CRISPR/Cas9 genome editing by Bogomiakova, M.E., Sekretova, E.K., Eremeev, A.V., Shuvalova, L.D., Bobrovsky, P.A., Zerkalenkova, E.A., Lebedeva, O.S., Lagarkova, M.A.

“…The mismatch of HLA haplotypes between donor and recipient adversely affects the outcome of tissue transplantation. TheB2Mgene knockout (B2M-KO) disrupts the…”
Get full text

At Home among Strangers: Is It Possible to Create Hypoimmunogenic Pluripotent Stem Cell Lines? by Bogomiakova, M. E., Eremeev, A. V., Lagarkova, M. A.

“…Human pluripotent stem cells, which include embryonic stem cells and induced pluripotent cells (iPSCs), are capable of unlimited division and differentiation…”
Get full text

Derivation of Induced Pluripotent Stem Cells Line (RCPCMi009-A-1) with Knockout of the UBE2A Gene Using CRISPR/Cas9 Genome Editing by Khomyakova, E. A., Fedorenko, A. V., Surdina, A. V., Volovikov, E. A., Belikova, L. D., Zerkalenkova, E. A., Lagarkova, M. A., Bogomazova, A. N.

“…The deletions and mutations in the UBE2A gene cause X-linked mental retardation syndrome of the Nascimento type first described in 2006 (Nascimento et al.,…”
Get full text

The Role of Mutant RNA in the Pathogenesis of Huntington’s Disease and Other Polyglutamine Diseases by Bogomazova, A. N., Eremeev, A. V., Pozmogova, G. E., Lagarkova, M. A.

“…— Polyglutamine diseases are rare, inherited neurodegenerative pathologies that arise as a result of expansion of trinucleotide CAG repeats in the coding…”
Get full text

Clinical and Immunological Analysis of Retinal Pigment Epithelium Transplantation Derived from Induced Pluripotent Stem Cells under Pharmacological Immunosuppression in Rabbits by Neroeva, N. V., Balatskaya, N. V., Brilliantova, A. G., Katargina, L. A., Kharitonov, A. E., Lagarkova, M. A., Bogomazova, A. N.

“…justification . Degenerative retinal diseases associated with retinal pigment epithelium damage are untreated and lead to irreversible vision loss. The most…”
Get full text

Generation of induced pluripotent stem cell line RCPCMi008-A derived from patient with spinocerebellar ataxia 17 by Shuvalova, L.D., Davidenko, A.V., Eremeev, A.V., Khomyakova, E.A., Zerkalenkova, E.A., Lebedeva, O.S., Bogomazova, A.N., Klyushnikov, S.A., Illarioshkin, S.N., Lagarkova, M.A.

“…IPSC line RCPCMi004-8 was generated from skin fibroblasts collected from a male patient with spinocerebellar ataxia 17. The patient has expanded trinucleotide…”
Get full text

“Necessity Is the Mother of Invention” or Inexpensive, Reliable, and Reproducible Protocol for Generating Organoids by Eremeev, A. V., Volovikov, E. A., Shuvalova, L. D., Davidenko, A. V., Khomyakova, E. A., Bogomiakova, M. E., Lebedeva, O. S., Zubkova, O. A., Lagarkova, M. A.

“…Organoids are three-dimensional (3D) cell cultures that replicate some of the key features of morphology, spatial architecture, and functions of a particular…”
Get full text

Differences in Protein Secretion by Multipotent Mesenchymal Stromal Cells Effective and Ineffective in the Prevention of Acute Graft—Versus—Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation by Petinati, N. A., Drize, N. I., Arapidi, G. P., Shender, V. O., Lagar’kova, M. A., Kuz’mina, L. A., Parovichnikova, E. N., Savchenko, V. G.

“…Multipotent mesenchymal stromal cells (MSC) were administered to patients after allogeneic hematopoietic stem cell transplantation to prevent the development…”
Get full text

Morphological Characterization of Astrocytes in a Xenograft of Human iPSCDerived Neural Precursor Cells by Voronkov, D N, Stavrovskaya, A V, Guschina, A S, Olshansky, A S, Lebedeva, O S, Eremeev, A V, Lagarkova, M A

“…Transplantation of a mixed astrocyte and neuron culture is of interest in the development of cell therapies for neurodegenerative diseases. In this case, an…”
Get full text

Corrigendum to “Generation of two iPSC lines from healthy donor with a heterozygous mutation in the VPS13B gene” [59 (2022) 102648] by Chechetkina, S.A., Khabarova, A.A., Chvileva, A.S, Kurchenko, O.M., Smirnov, A.V., Yunusova, A.M., Kotov, I.N., Musatova, E.V., Pomerantseva, E.A., Volovikov, E.A., Lagarkova, M.A., Shnaider, T.A., Pristyazhnyuk, I.E.

Get full text

Generation of induced pluripotent stem cell line RCPCMi004-A derived from patient with Parkinson's disease with deletion of the exon 2 in PARK2 gene by Shuvalova, L.D., Eremeev, A.V., Bogomazova, A.N., Novosadova, E.V., Zerkalenkova, E.A., Olshanskaya, Yu.V., Fedotova, E.Y., Glagoleva, E.S., Illarioshkin, S.N., Lebedeva, O.S., Lagarkova, M.A.

“…IPSC line RCPCMi004-A was generated from skin fibroblasts collected from a male patient with early onset Parkinson's disease. The patient carries a…”
Get full text

Generation of two iPSC lines from healthy donor with a heterozygous mutation in the VPS13B gene by Chechetkina, S.A., Khabarova, A.A., Chvileva, A.S., Kurchenko, O.M., Smirnov, A.V., Yunusova, A.M., Kotov, I.N., Musatova, E.V., Pomerantseva, E.A., Volovikov, E.A., Lagarkova, M.A., Shnaider, T.A., Pristyazhnyuk, I.E.

“…The human induced pluripotent stem cell (iPSC) lines, iCS-MAF1-1 and iCS-MAF1-11, were generated from fibroblasts. The donor has a heterozygous mutation in the…”
Get full text

Gap junctional intercellular communication in human embryonic stem cells during spontaneous differentiation by Sharovskaya, Yu. Yu, Lagarkova, M. A., Kiselev, S. L., Chailakhyan, L. M.

Get full text

Cloning and characterization of TNKL, a member of tankyrase gene family by Kuimov, A N, Kuprash, D V, Petrov, V N, Vdovichenko, K K, Scanlan, M J, Jongeneel, C V, Lagarkova, M A, Nedospasov, S A

“…By serological screening of a breast tumor cDNA library we have identified a novel human gene, tnkl, encoding an ankyrin-related protein with a high degree of…”
Get full text