Search Results - "M., Yiamunaa"
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Plasma Tryptophan-Kynurenine Pathway Metabolites and Risk for Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes
Published in Diabetes care (01-12-2023)“…We sought to study the associations between plasma metabolites in the tryptophan-kynurenine pathway and the risk of progression to end-stage kidney disease…”
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Association of plasma angiogenin with risk of major cardiovascular events in type 2 diabetes
Published in Cardiovascular diabetology (15-02-2024)“…Angiogenin, an enzyme belonging to the ribonucleases A superfamily, plays an important role in vascular biology. Here, we sought to study the association of…”
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Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
Published in Nature communications (06-06-2019)“…Genetic factors underlying leukocyte telomere length (LTL) may provide insights into telomere homeostasis, with direct links to disease susceptibility. Genetic…”
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Plasma proteomics of diabetic kidney disease among Asians with younger-onset type 2 diabetes
Published in The journal of clinical endocrinology and metabolism (16-04-2024)“…Patients with younger onset of type 2 diabetes (YT2D) have increased risk for kidney failure compared to those with late onset. However, the mechanism of…”
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Association of Genetic Variants for Plasma LRG1 With Rapid Decline in Kidney Function in Patients With Type 2 Diabetes
Published in The journal of clinical endocrinology and metabolism (01-08-2021)“…Abstract Context Elevated levels of plasma leucine-rich α-2-glycoprotein 1 (LRG1), a component of transforming growth factor beta signaling, are associated…”
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Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes
Published in Journal of lipid research (01-06-2024)“…Circulating ceramide levels are dysregulated in kidney disease. However, their associations with rapid decline in kidney function (RDKF) and end-stage kidney…”
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Genetic Risk Score for Plasma Uric Acid Levels Is Associated With Early Rapid Kidney Function Decline in Type 2 Diabetes
Published in The journal of clinical endocrinology and metabolism (16-06-2022)“…Observational studies have shown that elevated uric acid (UA) is associated with chronic kidney disease (CKD). However, whether the relationship is causal…”
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Genetic markers for urine haptoglobin is associated with decline in renal function in type 2 diabetes in East Asians
Published in Scientific reports (23-03-2018)“…Urine haptoglobin (uHP) level prospectively predicts diabetic kidney disease (DKD) progression. Here, we aim to identify genetic determinants of uHP level and…”
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Clinical variable-based cluster analysis identifies novel subgroups with a distinct genetic signature, lipidomic pattern and cardio-renal risks in Asian patients with recent-onset type 2 diabetes
Published in Diabetologia (01-12-2022)“…Aims/hypothesis We sought to subtype South East Asian patients with type 2 diabetes by de novo cluster analysis on clinical variables, and to determine whether…”
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Association of major candidate protein biomarkers and long-term diabetic kidney disease progression among Asians with young-onset type 2 diabetes mellitus
Published in Diabetes research and clinical practice (01-10-2024)“…We aim to determine the association of seven major candidate protein biomarkers and diabetic kidney disease (DKD) progression among Asians with young-onset…”
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Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
Published in Communications biology (03-05-2021)“…The role of low frequency variants associated with telomere length homeostasis in chronic diseases and mortalities is relatively understudied in the East-Asian…”
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Association of leukocyte telomere length with chronic kidney disease in East Asians with type 2 diabetes: a Mendelian randomization study
Published in Clinical kidney journal (01-11-2021)“…Background Chronic kidney disease (CKD) is common among people with type 2 diabetes (T2D), and increases the risk of kidney failure and cardiovascular…”
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Association of haptoglobin phenotype with incident acute myocardial infarction in Chinese patients with type 2 diabetes
Published in Cardiovascular diabetology (30-05-2019)“…Haptoglobin (Hp) is an abundant plasma protein with anti-oxidant properties. Hp polymorphism is associated with cardio-metabolic dysfunction but the allele…”
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Correlation of Telomere Length in Adipose Tissue and Leukocytes and its Association with Postsurgical Weight Loss
Published in Obesity (Silver Spring, Md.) (01-12-2020)“…Objective The aim of this study was to determine the relationship between telomere length (TL) in subcutaneous adipose tissue (SAT), visceral adipose tissues…”
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Associations of young onset age and genetic risk of beta cell dysfunction with glycaemic progression in individuals with type 2 diabetes
Published in Diabetes & metabolism (01-11-2021)“…•Patients with young-onset type 2 diabetes had a high risk of glycemic progression in 3-year follow-up•A low generic risk score of beta cell dysfunction was…”
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Ethnic disparities in relationships of obesity indices with telomere length in Asians with type 2 diabetes
Published in Journal of diabetes (01-05-2019)“…Background Obesity and shorter telomeres increase the risk for diabetes complications and mortality. However, the relationship between obesity and telomere…”
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Aortic pulse wave velocity, central pulse pressure, augmentation index and chronic kidney disease progression in individuals with type 2 diabetes: a 3- year prospective study
Published in BMC nephrology (20-08-2020)“…Pulse wave velocity (PWV), central pulse pressure and augmentation index are arterial stiffness- related hemodynamic parameters but their associations with…”
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Short Leukocyte Telomere Length Predicts Albuminuria Progression in Individuals With Type 2 Diabetes
Published in Kidney international reports (01-05-2018)“…Telomere length, a marker for biological aging, is implicated with diabetic kidney disease (DKD); however, the association between telomere length and…”
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Author Correction: Genetic markers for urine haptoglobin is associated with decline in renal function in type 2 diabetes in East Asians
Published in Scientific reports (07-09-2018)“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper…”
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