Search Results - "M Vergara"
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1
Liver innate immune cells and insulin resistance: the multiple facets of Kupffer cells
Published in Journal of internal medicine (01-08-2016)“…Obesity, which affects 600 million adults worldwide, is a major risk factor for type 2 diabetes (T2D) and insulin resistance. Current therapies for these…”
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2
Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs
Published in Nature communications (10-06-2014)“…Many forms of blindness result from the dysfunction or loss of retinal photoreceptors. Induced pluripotent stem cells (iPSCs) hold great potential for the…”
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3
Origin of supermassive black holes in massive metal-poor protoclusters
Published in Monthly notices of the Royal Astronomical Society (19-04-2022)“…ABSTRACT While large numbers of supermassive black holes have been detected at z > 6, their origin is still essentially unclear. Numerical simulations have…”
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4
Diagnosis and treatment of hepatitis B. What contributions can prisons make?
Published in Revista espanola de sanidad penitenciaria (01-09-2021)“…Hepatitis B is a parenterally and sexually transmitted infection. Vaccination for the disease is highly effective, and its inclusion in Spain as part of a…”
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Three-dimensional automated reporter quantification (3D-ARQ) technology enables quantitative screening in retinal organoids
Published in Development (Cambridge) (15-10-2017)“…The advent of stem cell-derived retinal organoids has brought forth unprecedented opportunities for developmental and physiological studies, while presenting…”
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6
Detection of Mild Traumatic Brain Injury by Machine Learning Classification Using Resting State Functional Network Connectivity and Fractional Anisotropy
Published in Journal of neurotrauma (01-03-2017)“…Traumatic brain injury (TBI) may adversely affect a person's thinking, memory, personality, and behavior. While mild TBI (mTBI) diagnosis is challenging, there…”
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7
Global instability by runaway collisions in nuclear stellar clusters: numerical tests of a route for massive black hole formation
Published in Monthly notices of the Royal Astronomical Society (02-05-2023)“…ABSTRACT The centres of galaxies host nuclear stellar clusters, supermassive black holes, or both. The origin of this dichotomy is still a mystery. Nuclear…”
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8
New Drug Discovery Paradigms for Retinal Diseases: A Focus on Retinal Organoids
Published in Journal of ocular pharmacology and therapeutics (01-01-2020)“…Retinal disease represents a growing global problem, both in terms of quality of life and economic impact, yet new therapies are not being developed at a…”
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9
Photoplethysmography pulse rate variability as a surrogate measurement of heart rate variability during non-stationary conditions
Published in Physiological measurement (01-09-2010)“…In this paper we assessed the possibility of using the pulse rate variability (PRV) extracted from the photoplethysmography signal as an alternative…”
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10
Retinal organoid light responsivity: current status and future opportunities
Published in Translational research : the journal of laboratory and clinical medicine (01-12-2022)“…The ability to generate human retinas in vitro from pluripotent stem cells opened unprecedented opportunities for basic science and for the development of…”
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11
Stem Cell Sources and Their Potential for the Treatment of Retinal Degenerations
Published in Investigative ophthalmology & visual science (01-04-2016)“…Stem cells offer unprecedented opportunities for the development of strategies geared toward the treatment of retinal degenerative diseases. A variety of…”
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12
A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide
Published in Nature protocols (01-12-2006)“…We describe a modification of the DNA extraction method, in which cetyltrimethylammonium bromide (CTAB) is used to extract nucleic acids from plant tissues. In…”
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13
The effect of preprocessing pipelines in subject classification and detection of abnormal resting state functional network connectivity using group ICA
Published in NeuroImage (Orlando, Fla.) (15-01-2017)“…Resting state functional network connectivity (rsFNC) derived from functional magnetic resonance (fMRI) imaging is emerging as a possible biomarker to identify…”
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14
Diurnal Human Activity and Introduced Species Affect Occurrence of Carnivores in a Human-Dominated Landscape
Published in PloS one (14-09-2015)“…Diurnal human activity and domestic dogs in agro-forestry mosaics should theoretically modify the diurnal habitat use patterns of native carnivores, with these…”
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15
Organoids for the Study of Retinal Development and Developmental Abnormalities
Published in Frontiers in cellular neuroscience (05-05-2021)“…The cumulative knowledge of retina development has been instrumental in the generation of retinal organoid systems from pluripotent stem cells; and these…”
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16
Lens regeneration: a historical perspective
Published in The International journal of developmental biology (2018)“…The idea of regenerating injured body parts has captivated human imagination for centuries, and the topic still remains an area of extensive scientific…”
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17
Dynamic functional network connectivity discriminates mild traumatic brain injury through machine learning
Published in NeuroImage clinical (01-01-2018)“…Mild traumatic brain injury (mTBI) can result in symptoms that affect a person's cognitive and social abilities. Improvements in diagnostic methodologies are…”
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18
Viscoelastic characterisation of carbon black reinforced rubber using the torsion pendulum: Guidelines and temperature sweep results
Published in Polymer testing (01-10-2022)“…A comprehensive set of guidelines on the use of the torsion pendulum for the viscoelastic characterisation of carbon black reinforced rubber is presented,…”
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19
Identifying Alcohol Use Disorder With Resting State Functional Magnetic Resonance Imaging Data: A Comparison Among Machine Learning Classifiers
Published in Frontiers in psychology (10-06-2022)“…Alcohol use disorder (AUD) is a burden to society creating social and health problems. Detection of AUD and its effects on the brain are difficult to assess…”
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20
Meta‐analysis: high‐dose proton pump inhibitors vs. standard dose in triple therapy for Helicobacter pylori eradication
Published in Alimentary pharmacology & therapeutics (01-10-2008)“…Summary Background The evidence on whether high‐dose proton pump inhibitors (PPIs) increase cure rates of Helicobacter pylori treatment has not been…”
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