Search Results - "M Silva, Saimon"
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Reagentless protein-based electrochemical biosensors
Published in Analyst (London) (02-05-2023)“…The creation of reagentless protein-based biosensors that are capable of monitoring molecular analytes directly in bodily fluids could revolutionize our…”
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2
Biodegradable bioelectronics for biomedical applications
Published in Journal of materials chemistry. B, Materials for biology and medicine (03-11-2022)“…Biodegradable polymers have been widely used in tissue engineering with the potential to be replaced by regenerative tissue. While conventional bionic…”
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Potential Pulse-Facilitated Active Adsorption of Lubricin Polymer Brushes Can Both Accelerate Self-Assembly and Control Grafting Density
Published in Langmuir (21-09-2021)“…Self-assembled lubricin (LUB) monolayers are an effective antiadhesive coating for biomedical applications. Long deposition times and limited control over the…”
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Rapid Point-of-Care Electrochemical Sensor for the Detection of Cancer Tn Antigen Carbohydrate in Whole Unprocessed Blood
Published in ACS sensors (25-11-2022)“…Improving outcomes for cancer patients during treatment and monitoring for cancer recurrence requires personalized care which can only be achieved through…”
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5
Growth factor delivery: Defining the next generation platforms for tissue engineering
Published in Journal of controlled release (28-07-2019)“…Growth factors play a crucial role in tissue engineering by directing the fate of cells and allowing the formation of tissues. Understanding the key…”
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Adhesion and Self-Assembly of Lubricin (PRG4) Brush Layers on Different Substrate Surfaces
Published in Langmuir (03-12-2019)“…Lubricin (LUB, aka PRG4), a mucin-like glycoprotein, is best known for the significant role it plays in the boundary lubrication, wear protection, and adhesion…”
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Micropatterning of porous silicon Bragg reflectors with poly(ethylene glycol) to fabricate cell microarrays: Towards single cell sensing
Published in Biosensors & bioelectronics (15-02-2019)“…The work presented here describes the development of an optical label-free biosensor based on a porous silicon (PSi) Bragg reflector to study heterogeneity…”
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Active and passive drug release by self-assembled lubricin (PRG4) anti-fouling coatings
Published in Journal of controlled release (01-12-2022)“…Electroactive polymers (EAPs) have been investigated as materials for use in a range of biomedical applications, ranging from cell culture, electrical…”
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Lubricin (PRG4) reduces fouling susceptibility and improves sensitivity of carbon-based electrodes
Published in Electrochimica acta (10-02-2020)“…In order to overcome the problems of reliability and accuracy often associated with electrochemical sensing in bioassays due to electrode surface fouling, we…”
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10
Calcium ions have a detrimental impact on the boundary lubrication property of hyaluronic acid and lubricin (PRG-4) both alone and in combination
Published in Colloids and surfaces, B, Biointerfaces (01-02-2024)“…Cartilage demineralisation in Osteoarthritis (OA) patients can elevate calcium ion levels in synovial fluid, as evidenced by the prevalence of precipitated…”
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Versatile Fabrication Approach of Conductive Hydrogels via Copolymerization with Vinyl Monomers
Published in ACS applied materials & interfaces (20-12-2017)“…Functionalized poly(ethylene dioxythiophene) (f-PEDOT) was copolymerized with two vinyl monomers of different hydrophilicity, acrylic acid and hydroxyethyl…”
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Novel Boundary Lubrication Mechanisms from Molecular Pillows of Lubricin Brush-Coated Graphene Oxide Nanosheets
Published in Langmuir (10-05-2022)“…There are numerous biomedical applications where the interfacial shearing of surfaces can cause wear and friction, which can lead to a variety of medical…”
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13
Tuning drug dosing through matching optically active polymer composition and NIR stimulation parameters
Published in International journal of pharmaceutics (15-02-2020)“…[Display omitted] Controlled release is at the forefront of modern bioscience as it aims to address challenges associated with the dosing of drugs within…”
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A Simple Electrochemical Swab Assay for the Rapid Quantification of Clonazepam in Unprocessed Saliva Enabled by Lubricin Antifouling Coatings
Published in ChemElectroChem (01-07-2020)“…The electrochemical sensing of clonazepam in samples of unprocessed saliva is reported, using commercially available reduced graphene oxide (rGO) screen…”
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15
Lubricin on Platinum Electrodes: A Low‐Impedance Protein‐Resistant Surface Towards Biomedical Implantation
Published in ChemElectroChem (15-03-2019)“…Biofouling on surfaces compromises the function of biomedical devices whose function involves contact with biological fluids. In the context of electrochemical…”
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Wired for Success: Probing the Effect of Tissue-Engineered Neural Interface Substrates on Cell Viability
Published in ACS biomaterials science & engineering (10-06-2024)“…This study investigates the electrochemical behavior of GelMA-based hydrogels and their interactions with PC12 neural cells under electrical stimulation in the…”
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A tissue-engineered neural interface with photothermal functionality
Published in Biomaterials science (25-07-2023)“…Neural interfaces are well-established as a tool to understand the behaviour of the nervous system recording and stimulation of living neurons, as well as…”
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Lubricin as a tool for controlling adhesion in vivo and ex vivo
Published in Biointerphases (01-03-2021)“…The ability to prevent or minimize the accumulation of unwanted biological materials on implantable medical devices is important in maintaining the long-term…”
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Cellular Interactions with Lubricin and Hyaluronic Acid–Lubricin Composite Coatings on Gold Electrodes in Passive and Electrically Stimulated Environments
Published in ACS biomaterials science & engineering (09-08-2021)“…In the field of bionics, the long-term effectiveness of implantable bionic interfaces depends upon maintaining a “clean” and unfouled electrical interface with…”
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A glassy carbon electrode modified with an iron N4-macrocycle and reduced graphene oxide for voltammetric sensing of dissolved oxygen
Published in Mikrochimica acta (1966) (01-03-2016)“…The authors describe a platform for the electrochemical reduction of oxygen. It is based on the use of a glassy carbon electrode (GCE) that was modified in a…”
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