Search Results - "M S McIntyre"

Predicting QT prolongation in humans during early drug development using hERG inhibition and an anaesthetized guinea‐pig model by Yao, X, Anderson, D L, Ross, S A, Lang, D G, Desai, B Z, Cooper, D C, Wheelan, P, McIntyre, M S, Bergquist, M L, MacKenzie, K I, Becherer, J D, Hashim, M A

“…Background and purpose: Drug‐induced prolongation of the QT interval can lead to torsade de pointes, a life‐threatening ventricular arrhythmia. Finding…”
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Endoplasmic reticulum calcium store regulates membrane potential in mouse islet beta-cells by J F Worley, 3rd, M S McIntyre, B Spencer, R J Mertz, M W Roe, I D Dukes

“…Glucose stimulation of islet beta-cell insulin secretion is initiated by membrane depolarization and an elevation in intracellular free calcium concentration…”
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Dependence on NADH produced during glycolysis for beta-cell glucose signaling by I D Dukes, M S McIntyre, R J Mertz, L H Philipson, M W Roe, B Spencer, J F Worley, 3rd

“…An increase in cytosolic ATP following glucose metabolism by pancreatic beta-cells is the key signal initiating insulin secretion by causing blockade of…”
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Hess Altitudes and Other Morphological Estimators of Glacier Equilibrium Lines by Graham Cogley, J, McIntyre, M. S

“…The Hess altitude h on a valley glacier is the altitude of that contour that is most nearly straight. The Kurowsky altitude k is the average of the glacier's…”
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Depletion of intracellular Ca2+ stores activates a maitotoxin-sensitive nonselective cationic current in beta-cells by J F Worley, 3rd, M S McIntyre, B Spencer, I D Dukes

“…Glucose stimulation of beta-cell insulin secretion is initiated by membrane depolarization coupled with an elevation in intracellular Ca2+ concentration…”
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Streptococcus grouping latex kits: evaluation of five commercially available examples by Davies, S., Gear, J.E., Mason, C.M., Mcintyre, S.M., Hall, L.

“…This study compares a recently introduced latex agglutination test for the serogrouping of β-haemolytic streptococci against four internationally used…”
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Evaluation of a new Staphylococcus aureus latex agglutination kit, Prolex Staph Xtra, against other third-generation kits by Davies, S., Mcintyre, S.M., Mckinven, A.

“…Staphylococcus aureus, including methicillin-resistant strains, continues to be a common cause of infection/colonisation, which necessitates accurate and…”
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Therapists' differential countertransference reactions toward clients with major depression or borderline personality disorder by McIntyre, Sherri Martin, Schwartz, Robert C.

“…The purpose of this study was to examine psychotherapists' differential countertransference reactions toward either clients diagnosed with either Major…”
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Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling by Roe, M W, Worley, 3rd, J F, Mittal, A A, Kuznetsov, A, DasGupta, S, Mertz, R J, Witherspoon, 3rd, S M, Blair, N, Lancaster, M E, McIntyre, M S, Shehee, W R, Dukes, I D, Philipson, L H

“…Voltage-dependent delayed rectifier K+ channels regulate aspects of both stimulus-secretion and excitation-contraction coupling, but assigning specific roles…”
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Interaction between neurotransmitters and exogenous norepinephrine in isolated rat anococcygeus muscle by Mudumbi, Ramagopal V., Parmeter, Lonnie L., McIntyre, Margaret S., Leighton, H.Jeff

“…Continuous electrical field stimulation (EFS) elicited a sustained contraction and significantly increased the EC 50 value of norepinephrine (NE), shifting the…”
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Association between selective serotonin reuptake inhibitor and risk of peripheral artery disease in diabetes mellitus by Kai-Hua Chen, MD, Ting-Yao Wang, MD, Chuan-Pin Lee, PhD, Yao-Hsu Yang, MD, MSc, Roger S. McIntyre, MD, Mehala Subramaniapillai, BSc, Yena Lee, HBSc, Vincent Chin-Hung Chen, MD, PhD, Mihnea-Alexandru Găman

“…An increasing number of studies have demonstrated the bidirectional hemostatic effect of selective serotonin reuptake inhibitors (SSRIs) on the risk of…”
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Bipolar Disorder and Inflammation by Rosenblat, Joshua D., MD, McIntyre, Roger S., MD, FRCPC

“…The pathophysiology of bipolar disorder (BD) remains poorly understood. Current psychopharmacologic treatments are often poorly tolerated and carry high rates…”
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The impact of obesity on quality of life by Taylor, Valerie H., MD, PhD, Forhan, Mary, PhD, Vigod, Simone N., MD, McIntyre, Roger S., MD, Morrison, Katherine M., MD

“…An important association exists between obesity and mental illness that impacts all aspects of an individual's quality of life. This association can begin…”
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Further validation of an opioid risk assessment tool: the Brief Risk Interview by Jones, Ted, Lookatch, Samantha, Grant, Patricia, McIntyre, Janice, Moore, Todd

“…Opioids remain a common method of treating chronic pain conditions despite some controversy. In an effort to address some of the risks of opioid medications,…”
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National Trends in Parathyroid Surgery from 1998 to 2008: A Decade of Change by Greene, Andrew B., MD, Butler, Robert S., MS, McIntyre, Shannon, MS, Barbosa, German F., MD, Mitchell, Jamie, MD, Berber, Eren, MD, Siperstein, Allan, MD, Milas, Mira, MD

“…Background The introduction of limited explorations (LE) for parathyroidectomy broadened the management possibilities for hyperparathyroidism. We sought to…”
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Predictors of nonresponse to cognitive behavioural therapy or venlafaxine using glucose metabolism in major depressive disorder by Konarski, Jakub Z., MSc, Kennedy, Sidney H., MD, Segal, Zindel V., PhD, Lau, Mark A., PhD, Bieling, Peter J., PhD, McIntyre, Roger S., MD, Mayberg, Helen S., MD

“…Background Longitudinal neuroimaging investigations of antidepressant treatment offer the opportunity to identify potential baseline biomarkers associated with…”
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Aripiprazole for the maintenance treatment of bipolar I disorder: A review by McIntyre, Roger S., MD, FRCPC

“…Abstract Background: Bipolar disorder is a chronic neuropsychiatric syndrome associated with substantial rates of recurrence, interepisodic dysfunction,…”
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5.44 BODY WEIGHT DID NOT INFLUENCE ASENAPINE EFFICACY IN PEDIATRIC PATIENTS WITH BIPOLAR I DISORDER by Findling, Robert L., MD, MBA, McIntyre, Roger S., MD, Landbloom, Ronald L., MD, Wu, Xiao, PhD, Durgam, Suresh, MD

“…Objectives: Asenapine monotherapy is approved for the acute treatment of manic or mixed episodes associated with bipolar I disorder in pediatric patients (10…”
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Major depressive disorder and cognitive impairment by McIntyre, Roger S., MD

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Propranolol inhibits the human ether-a-go-go-related gene potassium channels by Xiaozhou Yao, McIntyre, Maggie S., Lang, Daniel G., Song, Ivy H., Becherer, James D., Hashim, Mir A.

“…Propranolol is a noncardioselective beta-adrenergic antagonist that has been recently reported to prolong the QTc interval on the surface electrocardiogram in…”
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