Search Results - "M S Boguski"

Proteins regulating Ras and its relatives by Boguski, Mark S, McCormick, Frank

“…GTPases of the Ras superfamily regulate many aspects of cell growth, differentiation and action. Their functions depend on their ability to alternate between…”
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Mutations in the Gene Encoding KRIT1, a Krev-1/rap1a Binding Protein, Cause Cerebral Cavernous Malformations (CCM1) by Sahoo, Trilochan, Johnson, Eric W., Thomas, James W., Kuehl, Peter M., Jones, Thomas L., Dokken, Charles G., Touchman, Jeffrey W., Gallione, Carol J., Lee-Lin, Shih-Queen, Kosofsky, Barry, Kurth, Janice H., Louis, David N., Mettler, Gabrielle, Morrison, Leslie, Gil-Nagel, Antonio, Rich, Steven S., Zabramski, Joseph M., Boguski, Mark S., Green, EricD, Marchuk, Douglas A.

“…Cerebral cavernous malformations (CCM) are congenital vascular anomalies of the brain that can cause significant neurological disabilities, including…”
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The Transcriptional Program in the Response of Human Fibroblasts to Serum by Iyer, Vishwanath R., Eisen, Michael B., Ross, Douglas T., Schuler, Greg, Moore, Troy, Jeffrey C. F. Lee, Trent, Jeffrey M., Staudt, Louis M., Hudson, James, Boguski, Mark S., Lashkari, Deval, Shalon, Dari, Botstein, David, Brown, Patrick O.

“…The temporal program of gene expression during a model physiological response of human cells, the response of fibroblasts to serum, was explored with a…”
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GenBank by Benson, Dennis A., Boguski, Mark S., Lipman, David J., Ostell, James, Ouellette, B. F. Francis, Rapp, Barbara A., Wheeler, David L.

“…The GenBank (Registered Trademark symbol) sequence database incorporates DNA sequences from all available public sources, primarily through the direct…”
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Experimental annotation of the human genome using microarray technology by Boguski, M. S, Shoemaker, D. D, Schadt, E. E, Armour, C. D, He, Y. D, Garrett-Engele, P, McDonagh, P. D, Loerch, P. M, Leonardson, A, Lum, P. Y, Cavet, G, Wu, L. F, Altschuler, S. J, Edwards, S, King, J, Tsang, J. S, Schimmack, G, Schelter, J. M, Koch, J, Ziman, M, Marton, M. J, Li, B, Cundiff, P, Ward, T, Castle, J, Krolewski, M, Meyer, M. R, Mao, M, Burchard, J, Kidd, M. J, Dai, H, Phillips, J. W, Linsley, P. S, Stoughton, R, Scherer, S

“…The most important product of the sequencing of a genome is a complete, accurate catalogue of genes and their products, primarily messenger RNA transcripts and…”
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Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1 by Chandrasekharappa, Settara C., Guru, Siradanahalli C., Manickam, Pachiappan, Olufemi, Shodimu-Emmanuel, Collins, Francis S., Emmert-Buck, Michael R., Debelenko, Larisa V., Zhuang, Zhengping, Lubensky, Irina A., Liotta, Lance A., Crabtree, Judy S., Wang, Yingping, Roe, Bruce A., Weisemann, Jane, Boguski, Mark S., Agarwal, Sunita K., Kester, Mary Beth, Kim, Young S., Heppner, Christina, Dong, Qihan, Spiegel, Allen M., Burns, A. Lee, Marx, Stephen J.

“…Multiple endocrine neoplasia-type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors in parathyroids, enteropancreatic…”
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A Physical Map of 30,000 Human Genes by Deloukas, P., Schuler, G. D., Gyapay, G., Beasley, E. M., Soderlund, C., Rodriguez-Tomé, P., Hui, L., Matise, T. C., McKusick, K. B., Beckmann, J. S., Bentolila, S., M.-T. Bihoreau, Birren, B. B., Browne, J., Butler, A., Castle, A. B., Chiannilkulchai, N., Clee, C., Day, P. J. R., Dehejia, A., Dibling, T., Drouot, N., Duprat, S., Fizames, C., Fox, S., Gelling, S., Green, L., Harrison, P., Hocking, R., Holloway, E., Hunt, S., Keil, S., Lijnzaad, P., C. Louis-Dit-Sully, Ma, J., Mendis, A., Miller, J., Morissette, J., Muselet, D., Nusbaum, H. C., Peck, A., Rozen, S., Simon, D., Slonim, D. K., Staples, R., Stein, L. D., Stewart, E. A., Suchard, M. A., Thangarajah, T., Vega-Czarny, N., Webber, C., Wu, X., Hudson, J., Auffray, C., Nomura, N., Sikela, J. M., Polymeropoulous, M. H., James, M. R., Lander, E. S., Hudson, T. J., Myers, R. M., Cox, D. R., Weissenbach, J., Boguski, M. S., Bentley, D. R.

“…A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The new gene map contains…”
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A Gene Map of the Human Genome by Schuler, G. D., Boguski, M. S., Stewart, E. A., Stein, L. D., Gyapay, G., Rice, K., White, R. E., Rodriguez-Tomé, P., Aggarwal, A., Bajorek, E., Bentolila, S., Birren, B. B., Butler, A., Chiannilkulchai, N., Chu, A., Clee, C., Cowles, S., Day, P. J. R., Dibling, T., Drouot, N., Dunham, I., Duprat, S., East, C., Edwards, C., J.-B. Fan, Fang, N., Fizames, C., Garrett, C., Green, L., Hadley, D., Harris, M., Brady, S., Hicks, A., Holloway, E., Hui, L., Hussain, S., C. Louis-Dit-Sully, Ma, J., MacGilvery, A., Mader, C., Maratukulam, A., Matise, T. C., McKusick, K. B., Mungall, A., Muselet, D., Nusbaum, H. C., Page, D. C., Peck, A., Perkins, S., Piercy, M., Qin, F., Quackenbush, J., Ranby, S., Reif, T., Rozen, S., Sanders, C., She, X., Silva, J., Slonim, D. K., Soderlund, C., W.-L. Sun, Tabar, P., Thangarajah, T., Vega-Czarny, N., Vollrath, D., Voyticky, S., Wilmer, T., Wu, X., Adams, M. D., Aufiray, C., Walter, N. A. R., Brandon, R., Dehejia, A., Goodfellow, P. N., Houlgatte, R., Hudson, J. R., Ide, S. E., Iorio, K. R., Lee, W. Y., Seki, N., Nagase, T., Ishikawa, K., Nomura, N., Phillips, C., Polymeropoulos, M. H., Sandusky, M., Schmitt, K., Berry, R., Swanson, K., Torres, R., Venter, J. C., Sikela, J. M., Weissenbach, J., Myers, R. M., Cox, D. R., James, M. R., Bentley, D., Deloukas, P., Lander, E. S., Hudson, T. J.

“…The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have been sampled to date in the form of expressed sequence tags. An…”
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Data management and analysis for gene expression arrays by Boguski, Mark S, Ermolaeva, Olga, Rastogi, Mohit, Pruitt, Kim D, Schuler, Gregory D, Bittner, Michael L, Chen, Yidong, Simon, Richard, Meltzer, Paul, Trent, Jeffrey M

“…Microarray technology makes it possible to simultaneously study the expression of thousands of genes during a single experiment. We have developed an…”
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Issues in searching molecular sequence databases by Altschul, Stephen F, Boguski, Mark S, Gish, Warren, Wootton, John C

“…Sequence similarity search programs are versatile tools for the molecular biologist, frequently able to identify possible DNA coding regions and to provide…”
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Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences by Makałowski, W, Zhang, J, Boguski, M S

“…A large set of mRNA and encoded protein sequences, from orthologous murine and human genes, was compiled to analyze statistical, biological, and evolutionary…”
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A novel RING finger protein interacts with the cytoplasmic domain of CD40 by Hu, H.M., O'Rourke, K, Boguski, M.S., Dixit, V.M.

“…CD40 is a member of the tumor necrosis factor receptor family and, like other members, it appears to possess no intrinsic signaling capacity (e.g. kinase…”
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GenBank by Benson, Dennis A., Boguski, Mark S., Lipman, David J., Ostell, James

“…The GenBank sequence database incorporates DNA sequences from all available public sources, primarily through the direct submission of sequence data from…”
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Evolutionary conservation and somatic mutation hotspot maps of p53 : correlation with p53 protein structural and functional features by WALKER, D. R, BOND, J. P, TARONE, R. E, HARRIS, C. C, MAKALOWSKI, W, BOGUSKI, M. S, GREENBLATT, M. S

“…Missense mutations in p53 frequently occur at 'hotspot' amino acids which are highly conserved and represent regions of structural or functional importance…”
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The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein by A W Opipari, Jr, M S Boguski, V M Dixit

“…We have previously identified in endothelial cells a gene product designated A20, that is rapidly and profoundly induced by tumor necrosis factor alpha (Dixit,…”
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A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis by Sikorski, R S, Boguski, M S, Goebl, M, Hieter, P

“…We have identified and characterized a novel, repeating 34 amino acid motif (the TPR motif) that is reiterated several times within the CDC23 gene product of…”
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Yeast genes and human disease by Bassett, Douglas E, Boguski, Mark S, Hieter, Philip

“…The experimental advantages of the budding yeast Saccharomyces cerevisiae are increasingly being exploited to elucidate the function of genes mutated in human…”
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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression by Schuetz, Erin, Kuehl, Peter, Zhang, Jiong, Lin, Yvonne, Lamba, Jatinder, Assem, Mahfoud, Schuetz, John, Watkins, Paul B, Daly, Ann, Wrighton, Steven A, Hall, Stephen D, Maurel, Patrick, Relling, Mary, Brimer, Cynthia, Yasuda, Kazuto, Venkataramanan, Raman, Strom, Stephen, Thummel, Kenneth, Boguski, Mark S

“…Variation in the CYP3A enzymes, which act in drug metabolism, influences circulating steroid levels and responses to half of all oxidatively metabolized drugs…”
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A YAC-based physical map of the mouse genome by Hudson, Thomas J, Lander, Eric S, Nusbaum, Chad, Slonim, Donna K, Harris, Katrina L, Birren, Bruce W, Steen, Robert G, Stein, Lincoln D, Miller, Joyce, Dietrich, William F, Nahf, Robert, Wang, Victoria, Merport, Olga, Castle, Andrew B, Husain, Zeeshan, Farino, Gail, Gray, Delphine, Anderson, Mechele O, Devine, Richard, Horton, Lloyd T, Ye, Wenjuan, Wu, Xiaoyun, Kouyoumjian, Vardouhie, Zemsteva, Irina S, Wu, Yi, Collymore, Alville J, Courtney, Dorothy F, Tam, James, Cadman, Matthew, Haynes, Andrew R, Heuston, Christine, Marsland, Tracy, Southwell, Anne, Trickett, Pamela, Strivens, Mark A, Ross, Mark T, Makalowski, Wojciech, Xu, Yixun, Boguski, Mark S, Carter, Nigel P, Denny, Paul, Brown, Steve D.M

“…A physical map of the mouse genome is an essential tool for both positional cloning and genomic sequencing in this key model system for biomedical research…”
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Genome cross-referencing and XREFdb: Implications for the identification and analysis of genes mutated in human disease by Bassett, Douglas E, Boguski, Mark S, Spencer, Forrest, Reeves, Roger, Kim, Su-hyon, Weaver, Theresa, Hieter, Philip

“…Comparative genomics approaches and multi-organismal biology are valuable tools for genetic analysis. Cross-species connections between genes mutated in human…”
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