Search Results - "M K, Sibin"

Circulatory levels of multiple microRNA associated with prediabetes by Misra, Pratibha, V., Athira S., R., Palaniswamy, K., Karthik, Vashum, Y., G., Ruchira, K., Sibin M.

“…Background Prediabetes is an intermediate condition which transits to diabetes mellitus on later stage. Identifying a noninvasive marker may help in the early…”
Get full text

Down regulation of human telomerase reverse transcriptase (hTERT) expression by BIBR1532 in human glioblastoma LN18 cells by Lavanya, C., Venkataswamy, Manjunatha M., Sibin, M. K., Srinivas Bharath, M. M., Chetan, G. K.

“…Increased telomerase activity can be blocked by targeting the hTERT activity at both RNA and catalytic subunits. Various inhibitors had been used to regulate…”
Get full text

Association of promoter methylation status of NRF2 and PNPLA3 genes in alcoholic liver disease by M. K., Sibin, Manrai, Manish, Singh, Ranveer, Mukherjee, Bhasker, Mishra, Yogendra, Singh, Mukesh U., Singh, Amandeep, Negi, Rakhi, Chandra, G. Bala, S. V., Athira, Misra, Pratibha

“…Background Alcoholic liver disease (ALD) is the leading cause of chronic liver disease. In the liver, metabolism of alcohol occurs through multiple mechanisms…”
Get full text

Factor XIII polymorphism and risk of aneurysmal subarachnoid haemorrhage in a south Indian population by Suvatha, Arati, Sibin, M K, Bhat, Dhananjaya I, Narasingarao, K V L, Vazhayil, Vikas, Chetan, G K

“…The rupture of a brain aneurysm causes bleeding in the subarachnoid space and is known as aneurysmal subarachnoid haemorrhage (aSAH). In our study, we…”
Get full text

Prognostic significance of factor XIIIA promoter methylation status in aneurysmal subarachnoid haemorrhage (aSAH) by Arati, S, Chetan, G K, Sibin, M K, Bhat, Dhananjaya I, Vazhayil, Vikas, Narasingarao, K V L

“…Aneurysmal subarachnoid hemorrhage is a life- threatening condition with high rate of disability and mortality. Apolipoprotein E (APOE) and Factor XIIIA (F13A)…”
Get full text

Correlation of CYP2R1 gene promoter methylation with circulating vitamin D levels among healthy adults by Varadharajan, Ashvin, Sibin, M, Athira, S, Ghosh, Arijit, Misra, Pratibha

“…Background & objectives: Despite being a tropical country, vitamin D deficiency is highly prevalent in India with studies indicating 40-99 per cent prevalence…”
Get full text

Association of CILP, COL9A2 and MMP3 Gene Polymorphisms with Lumbar Disc Degeneration in an Indian Population by S M, Harshitha, M K, Sibin, G K, Chetan, I Bhat, Dhananjaya

“…Lumbar disc degeneration (LDD) is a multifactorial disorder caused by genetic and environmental factors. Polymorphisms in several structural and inflammatory…”
Get full text

IL18RAP polymorphisms and its plasma levels in patients with Lumbar disc degeneration by MK, Sibin, SM, Harshitha, S, Arati, GK, Chetan, P Shukla, Dhaval, I Bhat, Dhananjaya

“…•Interleukin 18 Receptor Accessory Protein (IL18RAP) plays a role in lumbar disc degeneration.•Genotyping of two IL18RAP polymorphisms (rs1420106 and rs917997)…”
Get full text

Safe Biochemical Testing of COVID-19 Samples: A Clinical Lab Perspective by Misra, Pratibha, Bhatia, Kapil, Negi, Rakhi, Mukherjee, Bhasker, Sibin, MK

“…The current COVID-19 pandemic has not only greatly burdened healthcare system globally but also exposed the medical and paramedical staff to risk of infection…”
Get full text

RNA interference mediated downregulation of human telomerase reverse transcriptase (hTERT) in LN18 cells by Lavanya, Ch, Sibin, M. K., Srinivas Bharath, M. M., Manoj, M. Jeru, Venkataswamy, Manjunatha M., Bhat, Dhananjaya I., Narasinga Rao, K. V. L., Chetan, G. K.

“…Human telomerase reverse transcriptase (hTERT) gene is a biomarker for the targeted therapy in various cancers. Presence of increased telomerase activity is a…”
Get full text

CD133 and BMI1 expressions and its prognostic role in primary glioblastoma by SIBIN, M. K., LAVANYA, C. H., BHAT, DHANANJAYA I., RAO, NARASINGA, GEETHASHREE, N., VIBHUTI, W., CHETAN, G. K.

“…Glioblastoma is the most common malignant brain tumour, generated by bulk of malignant cancer stem cells, which express various stem cell factors like CD133,…”
Get full text

To study childhood trauma in patients with bipolar affective disorder and its association with leucocyte telomere length by Chauhan, V.S., Sibin, M.K., Yadav, Prateek, Sharma, Markanday

“…Childhood traumatic (CT) events are more frequent in Bipolar Affective Disorder (BD) than in healthy individuals. As per existing studies, telomere shortening…”
Get full text

Can the cardioprotective effect of microRNA-103 inhibitors be extended to women with polycystic ovary syndrome? by Ramaswamy, P, Sibin, M K, Misra, P, Sahu, R

Get more information

Alteration in serum miR126 expression in healthy adults observing Navratri fast by Naithani, Nardeep, Sibin, M K, Athira, S V, Negi, Rakhi, Misra, Pratibha

“…Fasting is practiced by various religions in the world. The previous studies show the effect of fasting on biochemical markers in healthy subjects; however, no…”
Get full text

Promoter methylation of PTEN gene in high grade gliomas by Lavanya, C, Chetan, GK, Sibin, MK, Jeru, Manoj M, Srinivas, Bharath MM

Get full text

Role of APOE and IL18RAP gene polymorphisms in cervical spondylotic myelopathy in Indian population by Diptiranjan, S., Harshitha, S.M., Sibin, M.K., Arati, S., Chetan, G.K., Bhat, Dhananjaya I.

“…•Cervical spondylotic myelopathy (CSM) is a progressive degenerative spine disease.•APOE gene polymorphism was associated with the risk of CSM.•There was no…”
Get full text

A pilot study on DNA hypermethylation status in promoter region of P16 gene in patients with sporadic breast cancer by Bhatia, Kapil, Misra, Pratibha, Soe, Yan Naing, Sibin, M K, Batra, H S, Shelly, Divya, Sampath, Sangeetha, Negi, Rakhi, Mukherjee, Bhasker, Jagani, Rajat

“…Epigenetic modification of cancer-related genes plays a role over and above their genetic alterations and contributes to the tumor initiation and progression…”
Get full text

The role of direct DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) in high grade malignant glioma by Manoj, M Jeru, Chetan, G K, Rao, KVL Narasinga, Venkatesh, HN, Sibin, MK, Lavanya, Ch

Get full text

Effect of rs11614913 Polymorphism on Mature miR196a2 Expression and its Target Gene HOXC8 Expression in Human Glioma by Sibin, M K, Harshitha, S M, Narasingarao, K V L, Dhananjaya, I Bhat, Dhaval, P Shukla, Chetan, G K

“…miRNA polymorphisms are recently identified as a risk factor for various cancers, and it is associated with change in the expression of target genes in vitro …”
Get full text

CDKN2A (p16) mRNA decreased expression is a marker of poor prognosis in malignant high-grade glioma by Sibin, M. K., Bhat, Dhananjaya I., Narasingarao, K. V. L., Lavanya, Ch, Chetan, G. K.

“…Human high-grade glioma is heterogeneous in nature based on pathological and genetic profiling. Various tumour suppressor gene alterations are considered as…”
Get full text