Search Results - "M Cavanaugh, John"
-
1
Neuronal Injury and Glial Changes Are Hallmarks of Open Field Blast Exposure in Swine Frontal Lobe
Published in PloS one (20-01-2017)“…With the rapid increase in the number of blast induced traumatic brain injuries and associated neuropsychological consequences in veterans returning from the…”
Get full text
Journal Article -
2
Quantitative relationship between axonal injury and mechanical response in a rodent head impact acceleration model
Published in Journal of neurotrauma (01-09-2011)“…A modified Marmarou impact acceleration model was developed to study the mechanical responses induced by this model and their correlation to traumatic axonal…”
Get more information
Journal Article -
3
Investigate the Variations of the Head and Brain Response in a Rodent Head Impact Acceleration Model by Finite Element Modeling
Published in Frontiers in bioengineering and biotechnology (18-03-2020)“…Diffuse axonal injury (DAI) is a severe form of traumatic brain injury and often induced by blunt trauma. The closed head impact acceleration (IA) model is the…”
Get full text
Journal Article -
4
Effects of interleukin-1 beta, interleukin-6, and tumor necrosis factor on sensitivity of dorsal root ganglion and peripheral receptive fields in rats
Published in European spine journal (01-10-2006)“…This study was designed to characterize the effects of low doses (0.5-5 ng) of pro-inflammatory cytokines, interleukin-1 beta (IL-1beta), interleukin-6 (IL-6),…”
Get full text
Journal Article -
5
Temporal assessment of traumatic axonal injury in the rat corpus callosum and optic chiasm
Published in Brain research (27-07-2012)“…Abstract Impaired axoplasmic transport (IAT) and neurofilament compaction (NFC), two common axonal pathology processes involved in traumatic axonal injury…”
Get full text
Journal Article -
6
Mechanical properties of spinal nerve roots subjected to tension at different strain rates
Published in Journal of biomechanics (2006)“…An understanding of the biomechanical and physiological properties of spinal nerve roots, particularly in response to tension, is critical in understanding the…”
Get full text
Journal Article -
7
Impaired axoplasmic transport is the dominant injury induced by an impact acceleration injury device: An analysis of traumatic axonal injury in pyramidal tract and corpus callosum of rats
Published in Brain research (03-05-2012)“…Abstract Traumatic axonal injury (TAI) involves neurofilament compaction (NFC) and impaired axoplasmic transport (IAT) in distinct populations of axons…”
Get full text
Journal Article -
8
Demonstration of substance P, calcitonin gene-related peptide, and protein gene product 9.5 containing nerve fibers in human cervical facet joint capsules
Published in Spine (Philadelphia, Pa. 1976) (01-06-2004)“…Human cervical facet joint capsules were evaluated by immunohistochemistry. To study the neuropeptide innervation of the cadaveric cervical facet joint…”
Get full text
Journal Article -
9
An evaluation of three-dimensional image–guided technologies in percutaneous pelvic and acetabular lag screw placement
Published in The Journal of surgical research (01-11-2013)“…Abstract Background Percutaneous stabilization using three-dimensional (3D) navigation system is a promising treatment for pelvic and acetabular fractures…”
Get full text
Journal Article -
10
Magnetic resonance imaging-based relationships between neck muscle cross-sectional area and neck circumference for adults and children
Published in European spine journal (01-02-2013)“…Background Computer models and human surrogates used to study the forces and motion of the human neck under various loading conditions are based solely on…”
Get full text
Journal Article -
11
Mechanical strain to maxillary incisors during direct laryngoscopy
Published in BMC anesthesiology (07-11-2017)“…While most Direct laryngoscopy leads to dental injury in 25-39% of cases. Dental injury occurs when the forces and impacts applied to the teeth exceed the…”
Get full text
Journal Article -
12
Effect of nucleus pulposus on the neural activity of dorsal root ganglion
Published in Spine (Philadelphia, Pa. 1976) (15-04-2001)“…This study was designed to investigate, using neurophysiologic techniques in an in vivo rat model, the effect of application of nucleus pulposus to the nerve…”
Get full text
Journal Article -
13
Effects of nucleus pulposus on nerve root neural activity, mechanosensitivity, axonal morphology, and sodium channel expression
Published in Spine (Philadelphia, Pa. 1976) (2004)“…This study analyzed the effects of autografted nucleus pulposus on nerve root axon morphology, neurophysiologic function, and sodium channel expression. To…”
Get full text
Journal Article -
14
Pain generation in lumbar and cervical facet joints
Published in Journal of bone and joint surgery. American volume (01-04-2006)“…Facet joints are implicated as a major source of neck and low-back pain. Both cervical and lumbar facet syndromes have been described in the medical…”
Get full text
Journal Article -
15
Dynamic Response of the Thoracolumbar and Sacral Spine to Simulated Underbody Blast Loading in Whole Body Post Mortem Human Subject Tests
Published in Annals of biomedical engineering (01-11-2021)“…Fourteen simulated underbody blast impact sled tests were performed using a horizontal deceleration sled with the aim of evaluating the dynamic response of the…”
Get full text
Journal Article -
16
Recording of neural activity from goat cervical facet joint capsule using custom-designed miniature electrodes
Published in Spine (Philadelphia, Pa. 1976) (15-06-2005)“…To establish a methodology for the neurophysiologic study of mechanoreceptors in the cervical facet joint capsule. To test a custom designed miniature dual…”
Get full text
Journal Article -
17
Correlation of mechanical impact responses and biomarker levels: A new model for biomarker evaluation in TBI
Published in Journal of the neurological sciences (15-12-2015)“…Abstract A modified Marmarou impact acceleration model was used to help screen biomarkers to assess brain injury severity. Anesthetized male Sprague–Dawley…”
Get full text
Journal Article -
18
Whole Body PMHS Response in Injurious Experimental Accelerative Loading Events
Published in Annals of biomedical engineering (01-11-2021)“…Previous studies involving whole-body post-mortem human surrogates (PHMS) have generated biomechanical response specifications for physically simulated…”
Get full text
Journal Article -
19
Lumbar facet pain: Biomechanics, neuroanatomy and neurophysiology
Published in Journal of biomechanics (01-09-1996)“…Idiopathic low back pain has confounded health care practitioners for decades. Although there has been much advance in the understanding of the biomechanics of…”
Get full text
Journal Article -
20
Spatial and temporal dynamics of HDACs class IIa following mild traumatic brain injury in adult rats
Published in Molecular psychiatry (01-03-2022)“…The fundamental role of epigenetic regulatory mechanisms involved in neuroplasticity and adaptive responses to traumatic brain injury (TBI) is gaining…”
Get full text
Journal Article