Search Results - "M C Glennon"

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion by PRENTKI, M, VISCHER, S, GLENNON, M. C, REGAZZI, R, DEENEY, J. T, CORKEY, B. E

“…Several approaches were used to test the hypothesis proposing a role for acyl-CoA esters in nutrient-induced insulin release (Prentki, M., and Matschinsky, F…”
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Turnover of inositol pentakisphosphates, inositol hexakisphosphate and diphosphoinositol polyphosphates in primary cultured hepatocytes by GLENNON, M. C, SHEARS, S. B

“…We have used a non-transformed cell model, the primary cultured hepatocyte, to explore the turnover of inositol hexakisphosphate, multiple isomers of inositol…”
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A Role for Malonyl-CoA in Glucose-Stimulated Insulin Secretion from Clonal Pancreatic β-Cells by Corkey, B E, Glennon, M C, Chen, K S, Deeney, J T, Matschinsky, F M, Prentki, M

“…To gain insight into the relationship between acyl coenzyme A (CoA) esters and glucose-induced insulin release, acyl-CoA profiles were determined in clonal…”
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Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells by PESTALOZZI, B. C, MCGINN, C. J, KINSELLA, T. J, DRAKE, J. C, GLENNON, M. C, ALLEGRA, C. J, JOHNSTON, P. G

“…We have analysed cell cycle variations in thymidylate synthase (TS) protein in asynchronously growing NCl H630 and HT 29 colon cancer and MCF-7 breast cancer…”
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Purification of an inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity from rat liver and the evaluation of its substrate specificity by K Nogimori, P J Hughes, M C Glennon, M E Hodgson, J W Putney, Jr, S B Shears

“…Hepatic inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity was detected in a 100,000 x g soluble fraction and a detergent-solubilized particulate…”
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Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome by CORKEY, B. E, HALE, D. E, GLENNON, M. C, KELLEY, R. I, COATES, P. M, KILPATRICK, L, STANLEY, C. A

“…This study examines the relationship between impaired fatty acid oxidation and the pathogenesis of Reye syndrome. We present a hypothesis proposing that many…”
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In vivo modulation of iododeoxyuridine metabolism and incorporation into cellular DNA by 5'-amino-5'-deoxythymidine in normal mouse tissues and two human colon cancer xenografts by KINSELLA, T. J, GLENNON, M. C, KUNUGI, K. A, LINDSTROM, M. J

“…This in vivo study examines the ability of 5'-amino-5'-deoxythymidine (5'-AdThd) to modulate 5-iododeoxyuridine (IdUrd) cellular metabolism in two human colon…”
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In situ imaging of agonist-sensitive calcium pools in AR4-2J pancreatoma cells. Evidence for an agonist- and inositol 1,4,5-trisphosphate-sensitive calcium pool in or closely associated with the nuclear envelope by M C Glennon, G S Bird, H Takemura, O Thastrup, B A Leslie, J W Putney, Jr

“…The activation of phospholipase C by hormones and neurotransmitters activates a complex combination of Ca2+ release and accumulation by intracellular…”
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Cell-specific patterns of oscillating free Ca2+ in carbamylcholine-stimulated insulinoma cells by Prentki, M, Glennon, M C, Thomas, A P, Morris, R L, Matschinsky, F M, Corkey, B E

“…The effect of the muscarinic agonist carbamylcholine on cytoplasmic Ca2+ concentration ([Ca2+]i was examined at the single cell level in clonal pancreatic…”
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Linked oscillations of free Ca2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract by Corkey, B E, Tornheim, K, Deeney, J T, Glennon, M C, Parker, J C, Matschinsky, F M, Ruderman, N B, Prentki, M

“…We show in the accompanying paper that the steady-state level of free Ca2+ maintained by the organelles of permeabilized RINm5F insulinoma cells varies…”
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Actions of vasopressin and the Ca2+-ATPase inhibitor, thapsigargin, on Ca2+ signaling in hepatocytes by GLENNON, M. C, BIRD, KWAN, C.-Y, PUTNEY, J. W

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Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines by McGinn, C J, Pestalozzi, B C, Drake, J C, Glennon, M C, Kunugi, K, Otterson, G, Allegra, C J, Johnston, P G, Kinsella, T J

“…Resistance to 5-fluorouracil (5-FU) has been associated with thymidylate synthase (TS) gene amplification and increased TS protein levels. Increased TS protein…”
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The 16s/23s ribosomal spacer region as a target for DNA probes to identify eubacteria by Barry, T, Glennon, C M, Dunican, L K, Gannon, F

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Lowering pH in Blood Platelets Dissociates Myosin Phosphorylation from Shape Change and Myosin Association with the Cytoskeleton by Nachmias, Vivianne T., Yoshida, Ken-ichi, Glennon, Clay

“…Platelet shape change induced by ADP is relatively independent of external pH over the range 6-7. If the chloride ion in the buffer is replaced by weak acids,…”
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Actions of vasopressin and the Ca(2+)-ATPase inhibitor, thapsigargin, on Ca2+ signaling in hepatocytes by M C Glennon, G S Bird, C Y Kwan, J W Putney, Jr

“…When hepatocytes were loaded with fura-2 by incubation with the acetoxymethyl ester (fura-2/AM), addition of Mn2+ resulted in a rapid quench of a fraction of…”
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Regulation of steady-state free Ca2+ levels by the ATP/ADP ratio and orthophosphate in permeabilized RINm5F insulinoma cells by Corkey, B E, Deeney, J T, Glennon, M C, Matschinsky, F M, Prentki, M

“…Stimulation of insulin secretion in the pancreatic beta-cell by a fuel such as glucose requires the metabolism of the fuel and is accompanied by increases in…”
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Epidermal growth factor‐induced increases in inositol trisphosphates, inositol tetrakisphosphates, and cytosolic Ca2+ in a human hepatocellular carcinoma‐derived cell line by Gilligan, Ann, Prentki, Marc, Glennon, Major C., Knowles, Barbara B.

“…A human hepatocellular carcinoma‐derived cell line, PLC/PRF/5, was examined for its ability to respond to epidermal growth factor (EGF) exposure with increased…”
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Selective activation of Ca2+ influx by extracellular ATP in a pancreatic beta-cell line (HIT) by Geschwind, J F, Hiriart, M, Glennon, M C, Najafi, H, Corkey, B E, Matschinsky, F M, Prentki, M

“…The action of exogenous ATP on cytoplasmic free Ca2+ ([Ca2+]i) was studied in insulin secreting cells using fura-2. Stimulation of clonal pancreatic beta-cells…”
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Prediction of outcome based on clinical seizure type in newborn infants by Brunquell, Philip J., Glennon, Christina M., DiMario, Francis J., Lerer, Trudy, Eisenfeld, Leonard

“…Objective: To determine whether the clinical features of neonatal seizures are of value in predicting outcome. Study design: Demographic features, clinical…”
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Actions of vasopressin and the Ca super(2+)-ATPase inhibitor, thapsigargin, on Ca super(2+) signaling in hepatocytes by Glennon, M C, Bird, GStJ, Kwan, C-Y, Putney, J W

“…When hepatocytes were loaded with fura-2 by incubation with the acetoxymethyl ester (fura-2/AM), addition of Mn super(2+) resulted in a rapid quench of a…”
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